Localized amyloidosis of the stomach.
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Amyloidosis↗
Biomedical subjects
F Uchino
Publications and source records attributed to F Uchino.
A filiform large cell lymphoma in the spleen: a case report with immunohistochemical and electron microscopic study.
We describe histological, immunohistochemical, and ultrastructural findings in a filiform large cell lymphoma of the spleen in a 73-year-old man. The spleen weighed 300 g and contained a nodular mass of dimensions 4 x 2.8 x 3 cm that was lobular, raised, and well circumscribed. Light microscopically, the lesion was composed of compact cellular aggregates having large nuclei with evenly dispersed chromatin and a single large nucleolus or occasionally two to three small nucleoli. Immunohistochemically, the tumor cells were reactive to antibodies to leukocyte common antigen and MBI. Electron microscopically, most tumor cells were covered with tall, delicate, filiform cytoplasmic projections resembling microvilli in number and distribution. Filiform cytoplasmic projections varied from 50 to 200 nm in width and were at right or oblique angles to the surface. They appeared to be parallel but were frequently undulated, curved, or branching, forming in places small tufts. The pattern was more clearly noted on thick sections examined at an accelerating voltage of 200 kV.
Aged↗
Membranocystic lesion in sclerosing lipogranuloma of the scrotum: an ultrastructural study.
Two cases of intrascrotal sclerosing lipogranuloma are reported in which affected adipose tissues showed peculiar membranocystic lesions (MCL) similar to the features described in Nasu-Hakola disease. On light microscopy, the MCL were seen in the degenerative fatty tissues and within multinucleated giant cells, which were positive for periodic acid-Schiff stain and resistant to diastase digestion. Ultrastructurally, two types of MCL were observed; one type was characterized by thick membranes composed of vesicular to minute tubular or fibrillar substructures, and the other type was characterized by thin membranes composed of only small numbers of tiny vesicles. The substructures in both types of MCL contained lipid droplets similar to those in the inner space. These results support the concept that the membranes in the MCL are derived from degenerated fat droplets.
Adult↗