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Biomedical subjects

F Schmidt

Publications and source records attributed to F Schmidt.

At least 217 records · Page 12Linked to original sources
PubMed1976

[Smoking ban at the workplace--the order of the hour (author's transl)].

Smoking is by far the most important inhalation noxa at the workplace and is probably to be considered most harmful to the workers generally during working hours. Tobacco smoking at the workplace also endangers the health of non-smokers through passive smoking. From this it is deduced that a general ban on smoking at the workplace is to be considered the order of the hour and as the most important aim of occupational medicine and industrial legislation at the present time.

Germany, West↗
PubMed1976

The isolation of IS1 and IS2 DNA.

DNA of the IS-elements IS1 and IS2 was prepared by digestion of appropriate heteroduplex molecules with endonuclease S1, followed by sucrose gradient centrifugation or gel electrophoresis. The material obtained is homogeneous with regard to size. The length of IS1 DNA is 820 +/- 65 nucleotides, the length of IS2 DNA is 1,350 +/- 70 nucleotides. IS1 DNA is not cleaved by the restriction endonucleases Eco R1, Hind II or Hind III. IS2 DNA is cleaved once by each of the two latter enzymes. The buoyand density determined by equilibrium centrifugation of Hg-complexes in Cs2so4 corresponds to a GC content of approximately 50%. Labelling with polynucleotide kinase indicates that both IS DNA's have a guanosyl residue at both of their 5'-termini.

Centrifugation, Density Gradient↗
PubMed1976

[Opinion to the vibrodilatation of the cervix in induced abortions - report of 2 years of experiences with the Soviet vibrodilatator WG-I].

The article discusses the techniques, the indications, the advantages and disadvantages of vibrodilatation on the basis of 2855 interruptiones of pregnancy up to the 12th months. No perforation, cervical injury or intraoperative bleeding due to the use of a WG-I vibrodilator was established in the authors' own patients. The average loss of blood was 164 ml and the periods of dilatation ranged from 6 to 44 seconds, with a failure rate of 5 per cent. The authors recommend that in cases of interruption of pregnancy vibrodilatation, involving very few complications, should be attempted as a rule before Hegar's classical dilatation is applied.

Abortion, Induced↗
PubMed1975

[Tumour inhibitory N-(bis--(2-chlorethyl)-aminomethyl)-urethanes (author's transl)].

The synthesis of N-[bis-(2-chlorethyl)-aminomethyl]-urethanes (I-VI) and N,N'-di[bis-(2-chlorethyl)-aminomethyl]-urea (VII) and their evaluation on the Yoshida sarcoma of the rat and on the sarcoma 180 of the mouse are described. The antitumor activity of I-VI is based on a reaction mechanism analogous to that of aromatic N-lost-derivatives.

Animals↗