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Biomedical subjects

F Saegesser

Publications and source records attributed to F Saegesser.

At least 91 records · Page 5Linked to original sources

[Chordomas. Excision of a lumbar chordoma: 2 1/2 years survival without signs of recurrence and without functional complications].

In connection with surgical removal of a chordoma in the lumbar region by large excision, followed by 31-month survival of the patient without complications, personal experience of 8 chordomas operated on over the last 20 years is reported. The authors believe their observations show the value of active surgical treatment combined with radiotherapy, which has a palliative effect on the pain and slows the evolution of the tumor. The effectiveness of surgical treatment and radiotherapy leads the authors to challenge the negative attitude generally taken towards the treatment of this condition and to adopt a position of moderate optimism.

Abdominal Muscles↗

[Bronchial and subpleural lipoma (author's transl)].

Three cases of bronchopulmonary lipomas are reported, two sub pleural and one endobronchial. They represent 2,8% of all so-called benign bronchopulmonary tumours in our statistic. The two subpleural and asymptomatic lipomas were treated by thoracotomy and enucleation, the third, the endobronchial lipoma required lobectomy because of irreversible pulmonary damage.

Adult↗

[Surgical treatment of pulmonary coin lesions found in cancer patients and 6 breast cancers. Solitary metastasis? 2d primary bronchopulmonary cancer? Coin lesions of benign nature?].

Pulmonary diffusion of breast cancer is frequent in those patients who have died of the disease and in those survivors who have not been cured after removal of the breast and X-ray treatment in the advanced states of the disease. When the metastases are identified, they are almost always multiple and bilateral. The appearance of a solitary, late, pulmonary coin lesion (metachrone), in someone with breast cancer certainly suggests a pulmonary metastase, but in fact, it is more likely to be a second cancer than a metastase, that is, a primary bronchopulmonary cancer. The presence of a solitary pulmonary coin lesion in someone who has or who has had breast cancer, presents therefore certain particular problems. After having controlled by xerotomography that there is no pulmonary diffusion in either lung, that there is no invasion of other tissues or organs, and after having controlled locally around the breast cancer, then it is imperative to remove the lesion without delay since it is certainly malignant and most probably a second cancer, that is, a primary bronchopulmonary cancer, an adenocarcinome, detected at an asymptomatic stage. The prognosis of a broncho-pulmonary adenocarcinome depends on the precocity of its removal.

Adenocarcinoma↗

[Clinical and nutritional status after jejuno-ileal shunt operation for exogenous morbid obesity].

Eight patients were operated upon for morbid obesity using strict criteria for operation. The average age was 35 years and average Broca's index 1.76. One patient underwent the Scott operation and seven the Buchwald-Varco procedure. There were neither postoperative deaths nor wound or bowel complications. The weight loss was 9.6% at the end of the 3rd postoperative week, and 24.6% at the end of the 4th postoperative month. Glycaemia and lipidaemia showed an important decrease upto the 3rd week postoperatively after which period this decrease became less marked. Electrolytes did not show any variation. Hepatic function tests indicated a slight increase at the 3rd postoperative week but normal levels at the later control. The frequency of diarrhoea varied between 8 and 10 liquid stools daily in the immediate postoperative period and 2-6 at the 4th month, without any pharmacological control. However, small intestinal shunts seem to create some favourable metabolic changes. Patient selection is important to the outcome of the operation. Long-term follow-up is mandatory since patients may develop medical complications.

Adult↗

[Bifocal bronchial granulocellular myoblastoma (Abrikosov's tumor)].

To the 44 observations of endobronchial granular cell myoblastoma described in the world literature can be added the case of a 52-year-old patient who presented with bifocal localization of this rare tumor of enigmatic origin. The two tumors were isolated from each other, one being situated at the level of the bronchus of the left superior lobe without implantation on the main bronchus, and the other at the bifurcation of the anterior segmental bronchus and left apico-dorsal segmental bronchus. The irreversible chronic-inflammatory peripheral lesions necessitated pneumonectomy. The patient is in excellent health 17 years after pneumonectomy. This is the fifth case of bifocal bronchial granular cell myoblastoma to be published.

Bronchial Neoplasms↗

[Recurrent massive hemorrhage of the distal part of the digestive tract due to hemorrhagic hereditary telangiectasia].

Massive gastrointestinal bleeding is known to occur in patients presenting the hemorrhagic hereditary telangiectasis condition known as Rendu-Osler-Weber (ROW) disease. Bleeding is most frequent in the fourth decade. Endoscopic coagulation of upper gastrointestinal telangiectatic spots is nowadays possible even in the presence of active bleeding. In the lower digestive tract the naevi are basicallly located on the terminal ileum and the right colon; emergency coloscopic examination is difficult when active bleeding occurs. 10-15% of ROW patients present sudden life-threatening episodes of bleeding. The danger is aggravated through delayed diagnosis as well as difficulty in localizing the hemorrhagic area. Selective angiogram of the three digestive arteries is a safe and efficient method of diagnosing the nature and source of the bleeding. It should be obtained routinely, on an emergency basis, before surgery. Operation includes removal of the involved part of the digestive tract. A specimen angiogram should be obtained during the procedure, to make sure that the bleeding malformation has been removed. Laparotomy without preliminary angiogram is likely to be unsuccessful. An illustrative case is presented.

Aged↗

[Pneumoblastomas. Apropos of 2 cases].

Pulmonary blastomas, also referred to as embryonal carcinosarcomas or, in the past, embryomas, are rare tumors of which thirty cases have been described in English, German, and Italian publications. We present two typical pulmonary blastomas one in a 43-year-old man and the other in an infant of six months, the youngest case yet reported. Several arguments exist in favor of the embryonic origin of these neoplams: their histogenesis, their resemblance to nephroblastomas, their bifocal or multifocal presence in certain cases, and in about one third of all cases their discovery in patients under 20 years of age. Histologically the tumoral tissue contains two components: an epithelial component in which tubes resembiling fetal bronchi are found, and a loose mesenchymal component of an embryonic type containing various areas of differentiation. Although some tumors evolve slowly or have been known for years, most of the time the appearance of symptoms is soon followed by hematogenous dissemination and rapid demise. Our two patients died quickly: the infant from mediastinal compression with cardiorespiratory insufficiency, and the adult form metastatic dissemination.

Adult↗