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Biomedical subjects

F Mariani

Publications and source records attributed to F Mariani.

At least 55 records · Page 3Linked to original sources
PubMed1983

Italian study of cerebral reversible ischemic attacks. II. The hematocrit and hemoglobin distribution and its relationship between clinical pattern and angiographic abnormalities.

A clinical and angiographic study was conducted in 360 patients with previous reversible ischemic attacks (RIAs) in order to verify the influence of hematocrit, hemoglobin and red cell count within the normal range in the clinical picture of cerebral infarction and its relationship with angiographic atherosclerosis. No significantly different distribution of the three parameters considered has been found according to the presence and the degree of atherosclerosis. On the contrary, our data have shown a significant correlation between levels of hematocrit, hemoglobin and red cell count and some clinical aspects of the RIA when angiographic atherosclerosis is present.

Adult↗
PubMed1980

[Morphology, frequency and significance of intramural arterial lesions in sudden coronary death (author's transl)].

In 208 selected cases of sudden coronary death (SD) and in 97 normal subjects dying from accident (AD) the intramural arterial vessels have been studied. In only one instance a unique "atheromatous" embolus was found. Arterial platelet aggregates (AP) were seen in 70% of SD and 76% of AD cases. The average number of arteria vessels with AP per section was 2.2 in SD and 2.5 in AD group (the range was 1 to 15 vessels). No correlation was found with the type of blood stasis and with a longer survival time. The conclusion is that AP are a secondary, terminal, non pathogenic phenomenon. This was documented by the findings in 39 cases of thrombotic thrombocytopenic purpura. In the latter, despite severe platelet sequestration and aggregation associated to other severely ischemic or hypoxic factors (obstructive microangiopathy, anemia, hemorrhagic diathesis, convulsive neurologic disorders) no evidence of coronary heart disease was shown. Other pathologic findings were "stenosing myo-fibrous medial hyperplasia" and more rarely intimal thickening, perivascular fibrosis and subintimal nodular hyalinosis. No one of these conditions predominated in SD cases. The conclusion is that the diseases of the small coronary arteries do not play any role in the nautral history of sudden coronary death.

Coronary Disease↗
PubMed1978

[Spinal and spinal cord injuries in aviation medicine].

The causes of vertebral lesions in the course of flying are listed. An account is given of the dynamic forces required to bring about vertebral fracture and their mechanism. Reference is made to the most common sites of vertebral injury in crashes, particularly in the case of helicopters, and during catapulted seat ejection. Lastly, sites of vertebral fracture in parachutists are discussed.

Accidents, Aviation↗
PubMedDate not supplied

Assessment of inter-observer differences in the Italian multicenter study on reversible cerebral ischemia.

A standardized protocol was used for duplicate examination by two neurologists of the clinical history and neurological signs in 55 patients with reversible cerebral ischemia. One trained examiner from each of eight clinical centres involved in the Italian Cooperative Study on reversible cerebral ischemia participated in this research. Duplicate examination were compared in order to evaluate the percentage of agreement achieved in the responses. Several discrepancies relating to either historical data or neurological signs were detected. Possible causes of this disagreement are discussed. The inter-observer differences appear to be an important problem to be faced in cooperative studies on reversible ischemic attacks. The purpose of the study was to estimate these differences in the attempt to increase the degree of agreement by repeated training sessions and discussion between the different examiners. These efforts are needed to improve the quality of clinical investigations on reversible cerebral ischemia and to increase the validity of their results.

Evaluation Studies as Topic↗
PubMedDate not supplied

Italian multicenter study on reversible cerebral ischemic attacks: III--Influence of age and risk factors on cerebrovascular atherosclerosis.

The influence of age and other risk factors (history of hypertension and diabetes, cigarette smoking, dyslipidemia) on cerebral atherosclerosis was studied in 462 patients with RIA who had cerebral angiography. The degree of atherosclerosis was quantified using extracranial and intracranial cerebrovascular scores (ECS, ICS) based on the number and severity of the lesion in 11 extracranial and 21 intracranial arterial segments. Thirty-six percent of the patients under age 45 had a normal angiogram compared with 17% of the patients over 45. In the subgroup of patients with abnormal angiogram the mean ECS and ICS vascular scores were not significantly different in the two age groups. Cigarette smoking was the only risk factor to show a strong association with the extracranial score, and it was independent of the effect of age and other risk factors.

Adult↗