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Biomedical subjects

F Maiuri

Publications and source records attributed to F Maiuri.

At least 163 records · Page 9Linked to original sources
PubMedDate not supplied

Megadolichobasilar anomaly. Clinical and diagnostic considerations on 30 cases.

30 patients with megadolichobasilar artery, explored by angiography, are reported; 23 among them were first studied by computerized tomography and 4 by magnetic resonance. From the clinical point of view, 9 had transient ischemic attacks or definitive ischemia, 7 had subarachnoid or intracerebral hemorrhage, and 7 had deficits of the cranial nerves; in the other 7 cases the condition was incidentally discovered as isolated asymptomatic anomaly or with other unrelated lesions. Among the patients with ischemic symptoms, vertebrobasilar insufficiency and pontine infarction were the most common clinico-radiological findings. Among the patients with intracranial hemorrhage, four had associated aneurysm or arteriovenous malformations. CT and MR allow a correct diagnosis of this anomaly. MR seems to be superior to CT in delineating the relationship of the anomalous artery with the nervous structures, and the coexisting pathology.

Aged↗
PubMedDate not supplied

The role of real time B-mode ultrasonography in the follow-up of patients submitted to carotid endarterectomy.

Sixty-eight patients submitted to carotid endarterectomy for carotid stenosis have been studied periodically by B-mode real time ultrasonography. This non-invasive investigation allows to detect not only a recurrent stenosis, but also minor changes following endarterectomy, including suture, lesions from clamps, myointimal proliferation, and intimal flaps. We think that all patients submitted to carotid endarterectomy must be explored periodically by duplex scanning, in order to follow-up the normal and pathological changes of the arterial wall.

Aged↗
PubMedDate not supplied

Cavernous angioma of the pineal region.

The pineal region is one of the most rare localizations of intracranial cavernous angiomas, with only 8 cases reported up today. The Authors report a case of cavernous angioma of such localization and review the pertinent literature. Magnetic resonance allows the correct diagnosis of cavernous malformations on the basis of their typical aspect, even in the absence of histological verification. We suggest that this imaging technique will allow to identify more frequently pineal cavernomas preoperatively, thus avoiding useless irradiation.

Brain Neoplasms↗
PubMedDate not supplied

Epidermal growth factor receptor and tissue tumor markers in human intracranial neoplasms.

The content of the epidermal growth factor receptor (EGFr) and its relation to tissue CEA and NSE were examined in 22 intracranial neoplasms (18 primary intracranial tumors and 4 metastasis from lung cancer). The EGFr was measured by a radioligand assay on crude plasma membrane preparations. The tissue tumor markers (CEA and NSE) were measured on the high speed supernatant of tissue homogenates. In the primary intracranial tumors the EGFr was positive in 68%, CEA in 43% and NSE in 47% of all cases examined. As it concerns the metastasis from lung cancer the positivity was 75% for EGFr while for CEA and NSE was 50% and 32% respectively. These results suggest that the routine measurement of EGFr, associated with the determinations of tissue CEA and NSE could provide useful information on the type of the intracranial neoplasms.

Adult↗
PubMedDate not supplied

Sturge-Weber disease without facial nevus.

A rare case of Sturge-Weber syndrome without facial nevus and epileptic seizures is reported. The other cases of incomplete form of the disease reported in the literature showed occipital calcification and epileptic seizures without facial nevus, while in the present case also the convulsions were absent. The possible pathogenic mechanism is discussed. The CT findings of these incomplete forms include unilateral or often bilateral occipital calcifications with no evidence of contrast enhancement. The Authors conclude that the radiologic finding of bilateral gyriform calcifications in the occipital region must suggest the diagnosis of Sturge-Weber disease even in the absence of facial nevus and epileptic seizures.

Adult↗
PubMedDate not supplied

Intracranial lipomas. Diagnostic and therapeutic considerations.

Fourteen cases of intracranial lipomas are reported and 200 cases from the literature are reviewed. Intracranial lipomas are rare lesions of developmental origin, which mainly occur in the region of the corpus callosum, more rarely in the ambient, interpeduncular, cerebellopontine angle and sylvian cisterns. Although they are usually asymptomatic, they can sometimes show neurological symptoms, mainly epileptic seizures. Computerized tomography and magnetic resonance imaging usually lead to the diagnosis, because of the very low-density attenuation values of lipomas on CT scan and the short T1 and T2 on magnetic resonance. A direct surgical approach is only rarely indicated, whereas cases associated to hydrocephalus require a CSF shunt. The anticonvulsivant therapy usually results in remission of the seizures.

Adolescent↗
PubMedDate not supplied

Lipoma of the ambient cistern causing obstructive hydrocephalus.

A 62-year-old patient with lipoma of the ambient cistern and marked hydrocephalus is described. Intracranial lipomas are maldevelopmental lesions, which rarely produce neurological symptoms. The anatomopathological and clinical features of the lipomas of the ambient cistern are reviewed on the basis of the other reported cases. The importance of the computerized tomography and nuclear magnetic resonance for the diagnosis and the indications for the surgery are also discussed.

Brain Neoplasms↗
PubMedDate not supplied

Primary lymphoma of the cranial vault.

An exceptional case of a large intracranial extradural lymphoma arising from the skull and causing intracranial hypertension syndrome, in the absence of other localizations elsewhere in the body is described. Only another similar observation was reported in the literature. The diagnosis of this exceptional localization of lymphomas, which can mimic other intracranial tumors, is discussed on the basis of the computer-tomography findings and the usefulness of the radiotherapy is pointed out.

Female↗
PubMedDate not supplied

Paramedian hourglass epidermoid cysts extending in the middle and posterior cranial fossa.

Four cases of large paramedian hourglass epidermoid tumors extending both in the middle and posterior cranial fossa are reported and other 16 cases from the literature are reviewed. The length of the clinical history and the triviality of neurological symptoms in spite of the size of the tumor are emphasized. CT scanning well documents the extension of these epidermoids and usually consents to differentiate them from the arachnoid cysts. The subtemporal transtentorial approach is more advisable, although a two-stage operation by subtemporal and suboccipital route can be necessary in some cases. Nevertheless the difficulties and the risk of the surgical treatment make very hard the complete removal of the tumor in most cases.

Adult↗
PubMedDate not supplied

Late neurological dysfunction in adult lumbosacral lipoma.

The case of a 53-year-old woman with adult-onset neurological dysfunction secondary to spinal dysraphia and lumbosacral lipoma is presented. This condition not only affects children, but may produce neurological troubles also in adult age. This observation confirms that lumbosacral lipomas do not represent a static condition but carry the potential for late neurological dysfunction and therefore they should be treated in early life to prevent late complications. Besides the adult-onset urinary dysfunction and lumbosacral and sciatic pain should suggest the possibility of spinal dysraphia and lumbosacral lipoma.

Female↗