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Biomedical subjects

F Maiuri

Publications and source records attributed to F Maiuri.

At least 73 records · Page 4Linked to original sources
PubMed1994

Correlation between sex hormone receptors and peritumoral edema in intracranial meningiomas.

Fifty patients with intracranial meningiomas, verified histologically, are retrospectively analyzed to correlate the peritumoral brain edema with the positivity of estrogen receptors and progesterone receptors. The extent of edema was quantified on CT scan and/or MR. Monoclonal antibodies were used to test the estrogen receptors and the dextran-coated charcoal method was used to test the progesterone receptors. Significant levels of both receptors were found in 41 (82%) specimens. 80% of the cases with positive receptors had brain edema, in contrast to only 2 among 9 cases with negative receptors. Thus, the presence of brain edema has resulted to be correlated to the positivity of sex hormone receptors, although we did not find significant correlation between the amount of receptors and the amount of edema. The suggested mechanisms responsible for the brain edema surrounding intracranial meningiomas are discussed. We can suggest that progesterone may induce the secretion of some substances from meningioma cells, such as prostaglandins and biogenic amines, which may result in vagogenic edema.

Adult↗
PubMed1993

Long-term survival of low-grade astrocytomas of the cerebral hemispheres.

The authors have reviewed 6 patients operated on, with histologically proven diagnosis of grade-II astrocytomas who have survived more than 10 years even with many reoperations. Young age, pre- and postoperative neurological status, aspect of the tumor mass on CT and MRI, site of the tumor in non-high functional areas and extent of surgical removal are the most important variables in predicting length of survival. In young patients without severe neurological deficits and with astrocytic tumors located in non high-functional areas, very long survivals may be obtained even with many operations, when the interval between the recurrences is at least three years.

Adolescent↗
PubMed1993

Hydatid cyst of the lumbosacral spine with large pelvic mass.

A rare case of hydatid cyst of the lumbosacral spine, causing extensive destruction of the sacrum and a large pelvis mass, is reported; a cutaneous fistula from the pelvic cavity to the posterior lumbar region was also present. The patient was studied by computerized tomography and operated on by combined anterior and posterior approach. The sacral localization of the spinal hydatidosis and its extension into the pelvic cavity are unusual. CT and MR allow a good definition of the bone destruction and the abdominal and pelvic extensions. Radical removal of spinal hydatid cysts may be rarely accomplished, because of the extensive bone invasion, and multiple recurrences, requiring repeating operations, occur in most cases.

Adult↗
PubMed1993

Spontaneous cure of a ruptured intracranial aneurysm.

A rare case of spontaneous cure of an internal carotid artery aneurysm is reported; the progressive resolution of the spasm and the disappearance of the aneurysm have been confirmed by serial angiograms respectively performed two weeks, two months and four months after the hemorrhage. The other 14 reported cases of angiographically documented spontaneous cure of intracranial aneurysms are reviewed and the possible causes of spontaneous aneurysmal thrombosis, such as retarded cerebral circulation, arterial spasm, size of the neck, thrombosis of the feeding artery and antifibrinolytic therapy, are discussed.

Adult↗
PubMed1993

Rapid growth of a brain-stem cavernous angioma.

A rare case of rapidly enlarging cavernous angiomas of the cerebral hemispheres and brain stem in a child is reported. Rapid growth of cavernous malformations of the brain is rarely observed; it may be due to different mechanisms, including enlargement of the vascular channels, hemorrhage and cysts formation. The possibility of progressive enlargement of cavernomas makes periodical MR studies necessary in all cases. When the growth is radiologically documented, surgical removal is imperative even in patients with trivial symptoms.

Brain Neoplasms↗
PubMed1992

Olfactory groove meningioma and multiple aneurysms. Case report.

We report a case of a patient with olfactory groove meningioma associated with multiple aneurysms. The association between intracranial aneurysms and meningiomas is infrequent and perhaps it is due to chance alone; many theories have been formulated to explain it. In the cases with both lesions, meningiomas are more frequently located at level of the convexity while aneurysms are more often located at level of the anterior cerebral-anterior communicating artery complex or at level of the middle cerebral artery.

Adult↗
PubMed1990

Transient visual symptoms and carotid artery disease. Exploration by real-time B-mode echotomography.

The real-time B-mode echotomographies of 100 patients with transient visual symptoms have been reviewed and their findings have been compared with those of other 100 patients with transient ischemic attacks, who never had visual disturbances in their clinical history. The rate of pathologic echotomographies was higher in the group of patients with transient visual symptoms (72%), who also had a higher percentage (50% of the positive cases) of small or mild plaques without significant hemodynamic effects. The amaurosis fugax, particularly when associated with hemispheric ischemic symptoms, should suggest a carotid disease. The non-invasive exploration by real-time B-mode echotomography and Doppler with spectral analysis is the method of choice for the diagnosis of patients with transient visual symptoms.

Adult↗
PubMed1990

Visual involvement in primary non-Hodgkin's lymphomas.

This paper reviews the modalities of involvement of the visual function in patients with primary non-Hodgkin's lymphomas. They include the lymphomatous uveitis, the invasion of the orbital cavities and cavernous sinuses, and the involvement of the optic nerves, chiasm and optic tracts by lymphomatous lesions. Two cases of primary non-Hodgkin's lymphomas with visual disturbances are reported and the different mechanisms of visual pathway damage and clinical troubles are discussed from a large review of the pertinent literature.

Adult↗
PubMed1990

Megadolichobasilar artery and acute cerebrovascular pathology.

Sixteen patients with a megadolichobasilar artery and acute cerebrovascular symptoms are reported. All were explored by computerized tomography and vertebral angiography. Nine had transient ischaemic attacks or definitive ischaemic lesions, whereas 7 had subarachnoid or intracerebral haemorrhage. Among the patients with ischaemic troubles, vertebro-basilar insufficiency and pontine infarction were the most common clinico-radiological findings. Among the patients with intracranial haemorrhage, 4 had associated aneurysms or arteriovenous malformations, while 3 had subarachnoid or intracerebral haemorrhage with no vascular malformations on the angiograms. The possible relationships between the megadolichobasilar anomaly and the cerebral ischaemic or haemorrhagic pathologies are discussed also from a review of the pertinent literature.

Aged↗
PubMed1990

Diagnosis of carotid artery occlusion by duplex scanning.

This paper reviews 70 patients, with complete occlusion of the internal carotid artery, investigated by duplex scanning. The correlation between the echogenicity of the occlusion (anechogenic, hypoechogenic or hyperechogenic) and the time interval between the ischaemic symptoms and the ultrasonic investigation showed that some occlusions are hypoanechogenic and others hyperechogenic, in spite of the time interval, and consequently the echogenicity of the occlusion cannot be correlated with the time of its formation. Duplex scanning allows a correct diagnosis in almost all cases of carotid artery occlusion by comparison of the morphological and flowmetric data. The 95% sensitivity in 20 cases was explored by digital angiography also. It was concluded that angiography was usually unnecessary to confirm a carotid occlusion and its use could be limited to rare, doubtful, cases and to patients with contralateral stenosis i.e. candidates for surgery.

Aged↗
PubMed1990

Familial cerebral cavernous angiomas.

Three families with two or more members affected by cavernous angiomas of the brain are described and the other 17 reported in the literature are reviewed. The familial occurrence of cerebral cavernous angiomas has been considered a rare event; nevertheless, the experience of the authors (positive familiarity in three patients where two or more relatives have been explored radiologically) suggests that cavernous angiomas of the brain might be, at least in most cases, a familial disease. Therefore, when a patient with cerebral cavernous angioma is observed, a careful familial history and the exploration of the familial members by computerized tomography or better still by magnetic resonance must be performed. The high frequency of multiple lesions in familial cases, the surgical indications and the role of the ultrasonic prenatal diagnosis are also discussed.

Adolescent↗
PubMed1990

Giant aneurysm of the pericallosal artery.

A rare case of a giant aneurysm of the pericallosal artery, evaluated by computed tomography, magnetic resonance imaging, and angiography, is reported, and the other 7 cases in the literature are reviewed. Giant aneurysms are exceptional in the distal segments of the anterior cerebral arteries, and may simulate a callosal tumor or hematoma on computed tomographic scan. The clinical, radiological, surgical, and pathological findings of giant aneurysms of this location are discussed and the other reported cases are analyzed. The role of magnetic resonance imaging in diagnosing and characterizing giant aneurysms is stressed.

Adult↗
PubMed1990

CT indications for surgery and evaluation of prognosis in patients with spontaneous intracerebral haematomas.

This study retrospectively analyzes the CT findings of 50 patients with spontaneous intracerebral haematomas and correlates them with the clinical condition at admission and the outcome. The volume of the haematoma was well correlated with the outcome and was a very useful indicator for surgery. In patients with haematoma volume lower than 25 ml and above 80 ml there was no indication for surgery; in patients with haematoma volume between 25 and 50 ml the operation does not significantly modify the survival rate, but favours a more rapid and complete recovery of the neurological deficits, whereas a haematoma volume between 50 and 80 ml favours the rate of survival.

Adult↗
PubMed1990

Cerebral gliosarcomas: correlation of computed tomographic findings, surgical aspect, pathological features, and prognosis.

The cases of 5 patients with cerebral gliosarcomas examined by computed tomography are reported and the correlations among the computed tomographic (CT) findings, the surgical and histological aspects, and the prognosis are discussed. In some patients, these tumors appear on CT scan as intracerebral lesions, with large necrotic areas and peripheral contrast enhancement; this CT aspect, similar to that of glioblastomas, corresponds to a diffusely infiltrating growth of the tumor and the prevalence of a gliomatous component. In other patients, the tumor appears on the CT scan as a hyperdense mass with well-defined margins and homogenous contrast enhancement; this CT finding, which may mimic that of a meningioma, corresponds to a rather well-demarcated surgical aspect and the prevalence of sarcomatous component. In our series, we have also noticed a more prolonged survival in a patient with a CT aspect that suggested a meningioma and prevalence of the sarcomatous component.

Adult↗
PubMed1990

Giant intracranial varix associated with venous angioma and intracerebral hemorrhage.

A rare case of giant cerebral varix with venous angioma and intracerebral hemorrhage, surgically treated with good outcome, is reported. Varices and venous angiomas are infrequent in the clinical practice and are usually asymptomatic. Giant venous varices are less rarely associated with vein of Galen aneurysms or high flow arteriovenous shunts, whereas isolated giant varices are exceptional. Association of varix and venous angioma has been reported only in three instances. The radiological diagnosis of the cerebral venous malformation is briefly discussed.

Adolescent↗
PubMed1989

Lipoma of the sylvian region.

An exceptional case of lipoma of the sylvian region is described and the other seven reported cases are reviewed. The sylvian fissure is the most rare site of intracranial lipomas. Sylvian lipomas may be asymptomatic or present with epileptic seizures due to irritation of the cortex of the sylvian fissure. Only two previous cases have been diagnosed during life by computerized tomography and operated on; the deep location of these lipomas and their adherences to the sylvian cortex and the branches of the middle cerebral artery make radical removal impossible and dangerous.

Brain Neoplasms↗
PubMed1989

Giant sacral perineurial cyst. A case report.

A rare case of giant sacral perineurial cyst, causing sciatic pain, explored by myelography and computerized tomography, is reported. The cyst, associated with large erosion of the sacrum, was poorly visualized on the myelography, because of its large size, whereas it was better defined on CT scan. Sacral perineurial cysts are usually small and asymptomatic and rarely cause radicular symptoms. The radiological diagnosis and the treatment of these nerve root cysts are briefly discussed.

Adult↗