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Biomedical subjects

F M Hall

Publications and source records attributed to F M Hall.

At least 163 records · Page 9Linked to original sources

Radiographic assessment of anomalous bile ducts.

We report 5 radiologically documented cases of anomalous bile duct drainage of a segment of the right lobe of the liver and/or the cystic duct. These anomalies may be suspected on preoperative, intraoperative, or postoperative cholangiograms by the lack of visualization of the bile ducts draining a focal portion of the right lobe of the liver ("naked segment"). They may also be diagnosed definitively by direct duct opacification. Radiologic diagnosis prior to cholecystectomy may prevent inadvertent ligation or injury to the aberrant duct.

Bile Ducts↗

99Tcm-MDP, 67Ga-citrate and 111In-leucocytes for detecting prosthetic hip infection.

An assessment was made of the roles of 99Tcm-MDP, 67Ga-citrate and 111In-leucocytes in identifying infected hip prostheses. Fifty painful prosthetic hips were investigated with a 99Tcm-MDP bone scan and an 111In-labelled leucocyte scan (ILLS). In 32 cases, a 67Ga-citrate scan was also performed. Normal or focal MDP uptake was obtained only in uninfected hips. Diffuse uptake of MDP was obtained only in infected hips and in one case of non-septic synovitis which also produced a false positive ILLS. A focal MDP uptake superimposed on a diffuse pattern was obtained in both infected and uninfected hips. The ILLS was abnormal in eight out of 11 cases of infection and in two out of 39 cases without infection. The 67Ga scan was abnormal in five out of six cases of infection and in five out of 26 cases without infection. It was concluded that a 99Tcm bone scan should be performed first on a painful prosthetic hip, and that for detecting infection, an ILLS was more specific but less sensitive than a 67Ga-citrate scan.

Gallium Radioisotopes↗

Leucocyte and contaminant cell-bound activities resulting from the labelling of leucocytes with 111In-oxine.

A simple method is described for estimating the activities bound to leucocytes, erythrocytes, platelets and the free activity, as resulted from the preparation and labelling of leucocytes with 111In-oxine. Measurements are required only of 111In activity, suspension volumes, and platelet concentrations. The limitations of the method are discussed. When blood from a normal volunteer was labelled by an 111In-oxine manufacturer's recommended technique, the greatest proportion of activity was bound to leucocytes, and in addition, a significant proportion of the activity was found to be associated with platelets. If the number of centrifugations between sedimentation and labelling was reduced from two to one, the proportion of free activity increased at the expense of a reduction in leucocyte activity, but the platelet activity remained unchanged. The relative distribution of cell-bound and free activities was independent of the relative centrifugal force (85-450 g), and of the time (15-30 min) and the suspension volume (5-10 ml) used to incubate the cells with 111In-oxine.

Blood Platelets↗

Excretion of radioactivity in breast milk following injection of 99Tcm-DTPA.

Measurements were made of the concentration of radioactivity in the breast milk of a patient following a 2 mCi (74 MBq) 99Tcm-DTPA dynamic renal scan. The concentration of activity was 0.88 nCi-1 ml at 2.75 h after injection and it decreased exponentially with an effective halflife of 4.3 h. The potential radiation dose to a breast-fed infant was small enough to conclude that breast feeding need only be interrupted for 4 h after injection.

Adult↗

Shoulder arthrography: comparison of morbidity after use of various contrast media.

This prospective study compares immediate and delayed patient discomfort in 177 patients following shoulder arthrography using intraarticular combinations of metrizamide, meglumine/sodium diatrizoate, meglumine diatrizoate, lidocaine, epinephrine, and air. Patients receiving conventional ionic monomeric positive contrast media had a 60% (90/150) incidence of moderate or severe delayed exacerbation of their baseline symptoms; only 14% (3/21) of patients receiving metrizamide, a nonionic contrast medium, had similar levels of postprocedural discomfort. Morbidity was somewhat diminished with the use of double-contrast (45%, 34/75) rather than single-contrast (75%, 56/75) examinations, and with avoidance of sodium-containing contrast agents or epinephrine. Nonionic or monovalent polymeric contrast media, despite their present high cost, may be the agents of choice if single-contrast arthrography is performed in joints (such as the shoulder, hip, and temporomandibular) associated with a high incidence of post-procedural pain.

Air↗