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Biomedical subjects

F Lutz

Publications and source records attributed to F Lutz.

At least 253 records · Page 14Linked to original sources

Permeability changes of Ehrlich mouse ascites tumor cells induced by a cytotoxin from Pseudomonas aeruginosa.

Ehrlich ascites tumor cells from mice were damaged during in vitro incubation with a cytotoxin from Pseudomonas aeruginosa at concentrations of greater than 1 microgram/ml. After a short time the cells started to lose potassium whereas their sodium content increased. When the protein concentration of the incubation medium was adjusted to the protein concentration inside the cells, swelling and release of glucose-6-phosphate dehydrogenase was avoided. However, lysis of the cells still took place. Preincubation of cells with tetrodotoxin, 4-aminopyridine or tetraethylammonium did not influence damage to the cells. The cells showed a steep increase in toxin response between 17 degrees and 27 degrees C ranging from insensitivity to full sensitivity. An increase in electrical conductance was measured during incubation of cholesterol bilayer membranes with a cytotoxin concentration of 1 microgram/ml. The conductance was increased by a factor of ten within 30 min at 25 degrees C which indicates the involvement of membrane lipids in the cytotoxin action.

Animals↗

[Radiological findings in teeth and periodontium in a group of Swiss youths].

Bite-wing x-ray films of 1084 Swiss recruits were examined. Approximately 96% of the recruits showed signs of early bone loss around one or more teeth. Only a very small number had recognizable bone changes in furcation areas. Per recruit, 7.3 carious lesions were found; the majority of these were entirely within enamel. Of 6287 restored approximal posterior surfaces, 71.4% were inadequate. A number of these filled surfaces showed secondary caries.

Adolescent↗

[Clinical periodontal findings in a group of Swiss youths].

A clinical epidemiological examination of the health status of the teeth and supporting structures of 1084 recruits at a summer recruits-school was conducted. With one exception all of the Swiss cantons were represented among the recruits. Only one recruit had a clinically healthy periodontium; all of the others showed inflammatory changes of the gingivae. The average PDI was 3.58. In the majority of the recruits signs of early bone loss around one or more sites was observable. Teeth with markedly abraded chewing surfaces did not show an increased prevalence of bone loss. An examination of existing fillings and crowns revealed a large number of unsatisfactory filling margins. The average DMFT value of 14.5 was mainly the result of the high number of filled teeth.

Adolescent↗