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Biomedical subjects

F Kokot

Publications and source records attributed to F Kokot.

At least 469 records · Page 26Linked to original sources

[Aldosteroneia in acute kidney failure].

In 19 patients with acute renal insufficiency the plasma renin activity (PRA) and the aldosteronaemia were determined during the phase of anuria and oliguria. Significantly elevated PRA values were found while plasma aldosterone was only moderately elevated in the blood plasma. Apart from this a significantly negative correlation between the aldosterone level and the sodium and bicarbonate concentrations in the blood plasma were found. The lack of a significant positive correlation between PRA and plasma aldosterone levels suggests the participation of factors other than renin in the regulation of the aldosterone secretion in patients with acute renal insufficiency.

Acute Kidney Injury↗

Influence of extracorporeal dialysis on parathyroid hormone secretion in patients with acute renal failure.

Serum immunoreactive parathyroid hormone (iPTH) was estimated in 30 patients with renal failure before and after haemodialysis. All patients were anuric or oliguric at the time of the investigation. Pre-dialysis iPTH values were significantly elevated (3.4 ng/ml) as compared with normal subjects (less than 0.5 ng/ml). Simultaneously, a significant hypocalcaemia (4.15 mEq/litre) was confirmed which was negatively correlated with iPTH levels. After 7-8 h of haemodialysis using a calcium concentration of 4.0 mEq/litre in the dialysate, a significant drop of iPTH level to 1.8 ng/ml was noted.

Acute Kidney Injury↗

[Pathophysiology and clinical aspects of parathyroid hormone].

In this paper the contemporary knowledge about structure, metabolism, secretion, level in blood plasma and diagnostic significance of the parathyroid hormone (PTH) is summarized. The difficulties connected with PTH estimations in human plasma are especially emphasized.

Antibody Formation↗

[The behavior of the parathyroid hormone secretion in hemodialyzed patients with chronic kidney failure].

In 15 patients with chronic renal insufficiency the influence of the haemodialysis on the level of the blood serum of immune-reactive parathormone (iPTH). In the therapy of dialysis a wash with high calcium content (= 8 mg/100 ml) was used. After a single haemodialysis a decrease of the iPTH-level was observed. After a dialysis therapy lasting several months the values of the iPTH-concentration in 7 of 8 examined patients were significantly lower than before this therapy. The results cited prove that by means of a wash with high calcium content the increased PTH-secretion may be diminished in patients with chronic renal insufficiency.

Adult↗

Plasms renin acitivity in coarctation of aorta before and after surgery.

Plasma renin acitivity was measured in II cases of coarctation of the aorta before and after operation. The values of plasma renin activity in the recumbent position before operation were significantly lower than in the control group. After surgery plasma renin activity rose to normal levels. There was no correlation between plasma renin activity levels and arterial blood pressure. The renin-angiotensin system seems not to be involved directly in the maintenance of hypertension in patients with aortic coarctation.

Adolescent↗