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Biomedical subjects

F Kase

Publications and source records attributed to F Kase.

At least 19 recordsLinked to original sources
PubMed1993

Serum chemistry profiles for Lechwe waterbucks (Kobus leche): variations with age and sex.

1. Over an 8-year period, 19 biochemical parameters have been determined at various ages in the blood serum of 92 clinically healthy Lechwe waterbucks (Kobus leche), 33 males and 59 females. 2. Significant differences have been noted with age. In neonates, the lowest values of total proteins, glucose, creatinine, urea, AST, ALT and iron have been noted; the highest ones have been seen for cholesterol, alkaline phosphatase, calcium and phosphorus. 3. With regard to sex, raised values of glucose, urea, alkaline phosphatase and ALT, and lowered values of cholesterol, have been noted in juvenile females compared with males of the same age. 4. In adult females, higher levels of urea and cholesterol and lower levels of glucose, triglycerides and natrium have been recorded compared with males. 5. With sex and age, no significant changes have been found in the levels of GGT, magnesium, chlorides and copper. 6. Our findings are discussed with those abstracted from the literature for related species.

Aging↗
PubMed1993

A comparison of haemocoagulation tests in the experimental endotoxin model DIC and in rats whole-body irradiated by 250 Gy.

Based on comparing results of tests followed in the present work between the endotoxin model of the disseminated intravascular coagulation (DIC) and irradiated groups of rats we consider that after the whole-body irradiation by a high dose of 250 Gy, the DIC occurs, in spite of the fact that the first stage--hypercoagulation condition, can be hardly observed. In the experimental endotoxin model, an increase of activated partial thromboplastin test (APTT) values and prolongation of the thrombin time was observed up to 24 hours in both endotoxin doses. After both endotoxin doses, the fibrinogen level was transiently decreased with its subsequent increase. The fibrin monomers correspond to decreasing the fibrinogen level. After the first dose, they were positive between the 3rd and 12th hours and after the second dose, the positivity was observed 6 hours after the application. The antithrombin III level was decreased after 12 hours in both endotoxin doses. The thrombocyte count was considerably reduced already from the 6th hour after administering endotoxin to the end of the experiment. Considerable changes of the thrombocyte aggregation were observed only 3 hours after administering the second dose. When comparing the resulting values of these tests with values observed in irradiated animals, then we can see a certain agreement in the nature of the changes after the exposure to 250 Gy. The fibrinogen level was transiently decreased 3 hours after irradiation, when considerable changes in the thrombocyte aggregation also occurred.

Animals↗
PubMed1991

Sex and season-related differences of basic haematological values in the mountain reedbuck (Reduncula fulvorufula).

1. Basic haematological values in the peripheral blood of four male and 13 female mountain reedbucks (Reduncula fulvorufula) have been repeatedly estimated. 2. Comparing these results for both sexes, we noted pronouncedly lower haematocrit values and haemoglobin contents in females (statistical significance less than or greater than 1%). In the white blood cells only an increased proportion of neutrophils in females was apparent. 3. We have been unable to find seasonal related differences in the red and white blood overall picture of the cells during the summer and winter seasons with the exception of raised red cell counts and increased proportion of monocytes in the winter. The presented findings are compared and discussed with those abstracted from the literature.

Animals↗
PubMed1990

[Review: heparin. 1. Methods of determination and inhibitory mechanisms of some coagulation factors].

In a brief survey four groups of determining methods are reported for the purpose of monitoring the heparin therapy, with their advantages and disadvantages being assessed simultaneously. Emphasis is placed on the heterogeneity of heparin with approximately 120 fractions which are the cause of different manners of response and an impediment to the development of a rapid, reliable and economically advantageous method. Finally, all heparin factors in the plasma are enumerated and their mechanisms of action on individual coagulation factors are referred to.

Animals↗
PubMed1990

[Review: heparin. 2. Effect on thrombocytes, vascular walls and fibrinolysis].

In a brief survey the impact on thrombocyte functions and thrombocyte values caused by heparin and its fractions is reported, with the acute and immuno-allergic form of heparin-induced thrombopenia being widely dealt with. Furthermore, the relationship between heparin and vessel wall, particularly then its endothelial layer, is discussed and finally, its impact on the mechanisms of fibrinolysis is reported.

Animals↗
PubMed1987

Basic haematological values in the Cameroon goat (Capra hircus).

1. Basic haematological values in 165 Cameroon goats (Capra hircus) are reported. 2. The erythrocyte count, mean 14.36 x 10(12) l-1, ranged from 8.24 to 24.7 x 10(12) l-1; the haematocrit values, mean 0.304, varied from 0.20 to 0.38; the haemoglobin content, mean 113.4 g/l, was in the range from 83.0 to 143.0 g/l and the leukocyte count, mean 13.67 x 10(9) l-1, had lowest and highest values between 5.4 and 24.5 x 10(9) l-1. 3. Comparing these blood constituents in 47 male and 118 female Cameroon goats we demonstrated statistically significant lower values of the haematocrit and haemoglobin content and a statistically significant higher proportion of lymphocytes in the female animals. 4. In 16 pregnant and 30 non-pregnant female Cameroon goats, all animals older than 3 years, no statistically significant differences of the red blood picture were noted. 5. Also in three groups, assorted according to age, no significant changes in basic haematological parameters were seen. 6. During one year follow-up of some haematological parameters, statistically significant seasonal changes were found. 7. All presented data are compared with values abstracted from the literature and discussed.

Animals↗
PubMed1987

Basic haematological values in carnivores--II. The Felidae.

1. Basic haematological values in 34 animals of eight carnivorous species are reported. 2. In four Northern lynxs (Lynx lynx lynx), two male and two female animals, the mean values are given: erythrocyte counts 8.51 X 10(12)/l, haematocrit 0.392/l, haemoglobin content 148.0 g/l and leukocyte count 7.92 X 10(9)/l. 3. In six male pumas (Puma concolor missolensis) the mean values estimated are: erythrocyte count 9.35 X 10(12)/l, haematocrit 0.43/l, haemoglobin content 163.9 g/l and leukocyte count 7.73 X 10(9)/l. Individual values in one female puma are also given. 4. In six jaguars (Panthera onca), three male and three female animals, the mean values are given: erythrocyte count 8.27 X 10(12)/l, haematocrit 0.37/l, haemoglobin content 137.1 g/l and leukocyte count 15.15 X 10(9)/l. 5. Only individual values are reported in one clouded leopard (Neofelis nebulosa), in one leopard (Panthera pardus saxicolor), in one Corbett's tiger (Panthera tigris Corbetti) and in one Altaic tiger (Panthera tigris Altaica). 6. In four lions (Panthera leo leo), two male and two female animals, the mean estimated values are: erythrocyte count 10.14 X 10(12)/l, haematocrit 0.462/l, haemoglobin content 159.0 g/l and leukocyte count 11.05 X 10(9)/l. In six female cheetahs (Acinonox jubatus jubatus) the mean values estimated are: erythrocyte count 7.86 X 10(12)/l, haematocrit 0.373/l, haemoglobin content 142.8 g/l and leukocyte count 8.65 X 10(9)/l. For three male cheetahs only individual values are reported. 8. All results achieved are compared with those abstracted from the literature and discussed.

Animals↗
PubMed1987

Basic haematological values in carnivores--I. The Canidae, the Hyaenidae and the Ursidae.

Basic haematological values for 32 animals of four carnivore species are reported. In six adult wolves (Canis lupus) the mean values estimated for the erythrocyte count 7.48 X 10(12)/l, haematocrit 0.465/l, haemoglobin 172.0 g/l and leukocyte counts 7.33 X 10(9)/l are given. For five young wolves, these parameters were markedly decreased, only the white cell count was raised. In 14 hunting dogs (Lycaon pictus) the mean values estimated are: erythrocyte count 9.15 x 10(12)/l haematocrit 0.435/l, haemoglobin 179.2 g/l and leukocytes 12.95 X 10(9)/l. In six striped hyaenas (Hyaena hyaena) the mean estimated values are: erythrocyte count 8.11 X 10(12)/l, haemoatocrit 0.445/l, haemoglobin 178.0 g/l and leukocytes 13.95 X 10(9)/l. Only individual values for the reported parameters are given in the Asiatic black bear (Selenarctos thibetanus). All results are compared with values derived from the literature for animals under investigation and for the domestic dog (Canis familiaris).

Animals↗
PubMed1987

[The protein C inhibitory system].

The chemical and physical characteristics of the individual components of the protein-C inhibiting system, protein C, thrombomodulin, protein S and the inhibitor of the activated protein C are summarized in a survey, with their mutual relations and their physiological impact on the course of the coagulating and fibrinolytic systems being represented. Finally, the clinical implications of a hereditary and acquired protein C deficiency, of a diminished protein S level and a lowered inhibitor of the activated protein C are discussed. The complications caused by a rapid decline of protein C values after administration of coumarin derivates are referred too.

Blood Proteins↗
PubMed1986

Time-dependent influence of some sedating agents on basic haematological values in various artio- and perissodactylids.

Basic haematological values in 32 animals of five species were estimated after administration of sedating agents. In all species under investigation, a time-dependent decrease of erythrocyte counts, haematocrit values and haemoglobin content was noted during the first 30 min after sedation, for the following 30 min the lowered values remained essentially without any change in zebras. Derived parameters, mean corpuscular haemoglobin, mean corpuscular Hb concentration and mean corpuscular volume did not change during the period of observation. Only insignificant changes in leukocyte count and in the proportion of lymphocytes and neutrophiles were registered. The shortest possible time between sedation and blood sampling is recommended to minimalize a distortion especially in the red blood picture.

Animals↗
PubMed1985

Basic haematological values in the African buffalo (Syncerus caffer caffer) and in the red buffalo (Syncerus caffer nanus).

Basic haematological values in 13 African buffaloes (Syncerus caffer caffer), 11 cows and 2 bulls, and in 2 red buffaloes (Syncerus caffer nanus), 1 bull and 1 cow, are reported. In the African buffalo, the erythrocyte count--mean 9.76 X 10(12) 1(-1)--ranged from 6.72 to 12.42 X 10(12) 1(-1), the haematocrit values--mean 0.391--varied from 0.32 to 0.47 and the haemoglobin content--mean 148.17--was in the range from 122.1 to 172.5 g 1(-1). For the red buffalo only individual values are given. In the African buffaloes, the leukocyte counts--mean 7.39 X 10(9) 1(-1)--ranging from 5.1 to 12.4 X 10(9) 1(-1) were slightly increased compared with man. For the red buffalo only individual values are reported. These values are compared with data abstracted from the literature for related buffalo species. The age-dependent decrease of erythrocyte counts and the age-dependent rise of the eosinophile proportion in the differential count are discussed.

Aging↗