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Biomedical subjects

F Iida

Publications and source records attributed to F Iida.

At least 145 records · Page 8Linked to original sources
PubMed1982

Surgical evaluation of endoscopic retrograde cholangiography for biliary tract diseases.

We attempted to clarify the surgical usefulness and limitation of endoscopic retrograde cholangiography (ERC) by comparing with drip infusion cholangiography (DIC). ERC was carried out on 144 patients with clinical symptoms of biliary tract diseases. The success rate was 71.5 per cent. Indications for surgery were found in 83.9 per cent of the patients with positive ERC findings and in 50.5 per cent of the patients in whom ERC was successful. The false positive rate in ERC, as revealed during the surgery was 2.3 per cent. Failure of ERC occurred in 41 patients. Failure of cannulation was attributed to para-vaterian diverticulum in 11, post-gastrectomy states in 5, the duodenal papilla covered by a polyp or a large fold in 2, and choledocho-duodenal fistula in 1. The failure of cannulation in 22 could not be clearly defined. As ERC was successful in 3 out of 9 patients in whom this approach was unsuccessful in the first trial, ERC should probably be repeated if such was indeed required pre-operatively. Diagnostic significance of DIC before ERC revealed that such plays a definite role in screening patients.

Adolescent↗
PubMed1980

Clinicopathologic consideration of protein-losing enteropathy due to lymphangiectasia of the intestine.

The pathogenesis of intestinal lymphangiectasia and mechanism of enteric loss of serum protein has been discussed from the pathologic and roentgenologic viewpoints of the two patients with this disease. Enteric loss of serum protein was attributed to exudation of lymph from ruptured lymphatic vessels, resulting from non-specific multiple ulcers of the small intestine in one patient and malrotation of the gut in another.

Adult↗
PubMed1978

Histochemical studies of mucosubstances in metaplastic epithelium of the stomach, with special reference to the development of intestinal metaplasia.

Processes in the development of intestinal metaplasia of the stomach were investigated from the morphological and histochemical approaches using light and electron microscopic techniques. The specimens taken from 38 gastric carcinomas and 15 gastric and/or duodenal ulcers were subjected to this study. Morphological appearances of the intestinal metaplasia observed in routine examination with hematoxylin and eosin staining was able to divided into complete and incomplete metaplasia by the light and electron microscope histochemical stainings of the mucosubstances. The columnar cells at the area of the incomplete metaplasia had both the properties of the intestinal epithelia and the gastric foveolar epithelia. The incomplete as well as the complete metaplasia arose from the generative cells at the isthmus of the gland. The generative cells, however, sometimes gradually transformed to produce the complete metaplastic cells. The two processes of the development of the intestinal metaplasia were proposed and discussed.

Duodenal Ulcer↗
PubMed1978

Electron microscopic observation of scirrhous carcinoma of the stomach.

Electron microscopic findings obtained from seven scirrhous carcinomas of the stomach were analyzed dividing each carcinoma into superficial, deep, and peripheral parts. Proliferation of collagen fibrils, disappearance of plasma membranes, and extracellular release of cell organellae of cancer cells were considered to be peculiar findings to this type of cancer. These phenomena were observed frequently at the deep part of the cancer, but rarely at the peripheral and superficial parts. Replacement of damaged cells by the proliferated collagen fibrils at the central area of the cancer and disconnection of cancer cells from scirrhous lesion at the peripheral part were considered to contribute to the biological behaviour of this carcinoma.

Adenocarcinoma↗
PubMed1978

Diagnostic and therapeutic considerations of myogenic tumors of the duodenum.

Three cases of duodenal myogenic tumor are described in detail. All the three were surgically treated and the final diagnoses were histologically established. The three consisted of two leiomyomas and one leiomyosarcoma. To make clinical diagnosis, roentgenologic, endoscopic, and angiographic examinations were empolyed. The selective angiography was more reliable than endoscopic biopsy to make a differential diagnosis whether a tumor was benign or malignant. Surgical procedures were required not only for malignant myomatous lesions but also for benign lesions because the latter also produce a high incidence of hemorrhage from ulceration of the tumor. Out of the three cases, one was successfully treated by enucleation but the other two were undergone more extensive surgery such as a Whipple's procedure or wide resection of the duodenal wall with side-to-side duodenojejunostomy. Operative techniques are discussed in detail basing on the biological characteristics, location, and size of the tumor.

Duodenal Neoplasms↗
PubMed1978

Surgical and pathologic aspects of protein losing gastropathy.

The mechanism of protein loss from the gastric wall was investigated in patients with Ménétrier's disease, gastric polyps, and carcinoma of the stomach. In Ménétrier's disease, plasma protein was lost as glycoprotein in the gastric juice secreted from proliferated foveolar cells. Some of the gastric polyps also showed pathologic findings similar to that of Ménétrier's disease. As a treatment for the diffuse type of Ménétrier's disease, subtotal gastrectomy was recommended by presenting enough recovery from hypoproteinemia. A small amount of protein lost from the remaining portion of the stomach may be almost completely digested and reabsorbed from the intestine. In instances of carcinoma of the stomach, the mechanism of protein loss was speculated to be loss of lymph, blood or other interstitial fluids from opened capillaries of the cancerous surface. Complete removal of the carcinoma, therefore, certainly results in recovery from hypoproteinemia.

Blood Proteins↗
PubMed1977

Surgical significance of capsule invasion of adenoma of the thyroid.

Capsule invasion observed in instances of adenomas of the thyroid was studied in correlation with the clinical course of the patients. The invasion, as defined in the cut-off and turn-out of the collagen fibers in the capsule, occurred in eight of 611 adenomas. The clinical course of the eight patients revealed no recurrence of an adenoma, even though there was no antitumor drug therapy. On the other hand, recurrences of adenomas were found in five of the 603 patients with noninvasive adenoma, of the 603 patients with noninvasive adenoma. Capsule invasion, therefore, is not a cause for the recurrence of an adenoma. The recurrence may result from the leaving of microadenoma in the thyroid when the first operation took place. Capsule invasion cannot be considered as a histologic sign of malignant tumor of the thyroid.

Adenoma↗
PubMed1976

[Clinico-pathological study of chronic thyroiditis (author's transl)].

Although chronic thyroiditis has been recently noticed as an autoimmune disease, the histological classification based on clinico-pathological correlation is still vague at present. The specimens subjected to this study were taken by exploratory excision from 63 patients who were clinically diagnosed as chronic thyroiditis. Histological observation was done regarding the progress of pathologic changes in the thyroid gland. Lymphoid type (14 cases): lymph-follicle formation with scattered infiltration of lymphocytes was the predominant feature in this group. No definite alteration of the thyroi- epithelium was observed. Some of the so-called focal thyroiditis may be included in the early stage of this group. Some of them may develop into tremendous proliferation of lymphoid tissue in its late stage. Oxyphilic cell type (34 cases): oxyphilic alteration of the epithelium was predominant, but lymphocytic infiltrations observed in varying degrees was not an essential feature of this group. Fibrosis may possibly become more prominent with destruction of thyroid follicles in the late stage. Hyperplastic type (9 cases): most follicles were lined by cuboidal or tall epithelium with papillary infolding and contained thin colloid and some cell aggregates. This type of thyroiditis also may result in a proliferation of interlobular fibrous tissue in its more advanced stage. Fibrous type (6 cases): this type of thyroiditis is believed to be a late stage of the other three types. The original type of thyroiditis, however, was not clear because of advanced fibrosis. Evidences of the progress of the histological changes were observed in 12 out of 40 patients in whom the specimens were taken from both lobes and in two others whose specimens were taken twice at different stages. Clinical correlation of this classification was studied. The lymphoid type was found in 14 out of 53 female patients, but in none of 10 males. In age distribution the hyperplastic type was observed to be more common than the other types among younger people. The clinical signs of hypothyroidism were recognized most frequently in the oxyphilic cell type but not in the hyperplastic type. Thyroid function test, however, demonstrated no definite differences among the four types. Relationships were discussed in this paper between this author's classification and that of Woolner--also relationships to Hashimoto's thyroiditis and Riedel's struma.

Adult↗
PubMed1976

Mucous barrier and peptic ulcer of the stomach.

Mucous barrier was searched by the histochemical method of mucopolysaccharides and by the measurement of precipitated mucus of gastric juice. The neutral polysaccharide stored within the surface epithelial cells must be a source of the mucus of the gastric juice. The storage of the polysaccaride was decreased by a long-term stimulation by histamine, and the precipitated mucus volume was also decreased shortly after the stimulation. Therefore, some kind of the stimulation for the gastric secretion must be avoided for prevention of peptic ulcer. The oral administration of the sulfuric polysaccharide extracted from seaweed prevented the occurrence of experimental ulcer. It may be concluded that the exogeneous polysaccaride can take the place of the endogenous polysaccharide.

Animals↗