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Biomedical subjects

F H Bach

Publications and source records attributed to F H Bach.

At least 523 records · Page 29Linked to original sources
PubMed1971

Specificity of allogeneic cell recognition by human lymphocytes in vitro.

Human lymphocytes proliferate in vitro in response to foreign histocompatibility antigens that are present on allogeneic lymphocytes. Within a population of immunocompetent lymphocytes there are specific subpopulations that respond to allogeneic cells from different individuals. A means of selectively eliminating such subpopulations is suggested.

Bromodeoxyuridine↗
PubMed1970

Specificity of antigen recognition by human lymphocytes in vitro.

Delayed hypersensitivity reactions in vivo are exquisitely specific, in terms of both a lack of response after induction of tolerance and a response after sensitization. These studies in vitro demonstrate that this specificity, at least at the level of antigen recognition, is probably derived from different populations of cells, each responding to different antigens.

Antibody Specificity↗
PubMed1970

Cytotoxicity: specificity after in vitro sensitization.

Animals sensitized in vivo against an allogeneic tissue subsequently show accelerated rejection specificially of that or antigenically similar tissues. Lymphocytes sensitized in vitro will destroy target cells isogeneic with the sensitizing cells. Lymphocytes sensitized in vitro can differentiate specifically between different allogeneic target cells-as occurs in vivo.

Animals↗