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Biomedical subjects

F Giordano

Publications and source records attributed to F Giordano.

At least 145 records · Page 8Linked to original sources

Unusual morphologic features of a primary liver neoplasm.

Light and electron microscopy study of an unusual primary liver neoplasm observed in a 36-year-old woman. By light microscopy the tumor, initially detected by a needle biopsy and later surgically removed, was mainly composed of spindle-shaped and multinucleated cells which were similar to rhabdomyoblasts. These cells, however, showed ultrastructural features of hepatocytes.

Adult↗

[Mitral insufficiency associated with interatrial defect (ostium secundum). Problems of diagnosis and surgical treatment].

Of the 255 patients under observation of the AA. with ostium secundum interatrial defect who underwent surgery, 23 (9%) presented an associated mitral regurgitation. All patients had a hemodynamic test and a complete contrahistography, 8 patients polygraphic and 5 patients echocardiographic examinations. The clinical data alone, ecgraphic and Rx, supplied sufficient indications for a correct diagnosis in 87% of the cases. 22 patients underwent surgery: the septal defect was corrected in all patients, mitral regurgitation only in 9; in 5 by valve substitution, in 4 through conservative techniques. Only one patient died of cerebral coma. A report is made on the data relative to the clinical history, Rx, ecgraphic and hemodynamic examinations of the 23 patients under observation, the various anatomosurgical aspects of the valvular alterations, and the criteria adopted for the surgical correction of the mitral regurgitation.

Adolescent↗

Eosinophil granuloma of the scapula.

The writers present a case of eosinophil granuloma of the scapula. This is extremely rare at this site. They describe the clinical course, the unusual radiographic appearances, and the complete functional recovery following local resection.

Adolescent↗

Prenatal cytogenetic diagnosis: first 1,000 successful cases.

From February 1969 to August 1976, we studied 1,048 amniotic fluids. Of these, 958 (91.4%) were primarily for prenatal cytogenetic diagnosis. Cytogenetic studies were attempted in 1,021 cases; the diagnosis was successful in 1,000 of these. The failure rate of obtaining a diagnosis from the amniotic fluid cell culture of the first amniocentesis was 5% (50 cases); 29 cases had a repeat tap and successful diagnosis was achieved in all. In 21 cases, a repeat tap was refused. Thus, the overall failure rate of obtaining a final cytogenetic diagnosis was 2.06% (21/1,021). There were 32 fetal losses after amniocentesis including 16 spontaneous second trimester abortions, 7 fetal deaths in utero and 9 stillbirths. In two additional cases, fetal death had occurred before amniocentesis. This number of fetal losses does not exceed the number that would be expected in the same maternal age group without amniocentesis. In our series, the frequencies of trisomy in maternal age groups 40 years and over, 37-39 years, 35-36 years, and under 35 years were 4.5, 3.14, 0 and 0% respectively. These frequencies are comparable to those reported from other prospective prenatal studies and higher than those of retrospective live born studies. Various problems and pitfalls in prenatal cytogenetic diagnosis are discussed.

Adult↗

[Open heart mitral commissurotomy: experience with 286 cases (author's transl)].

A total of 286 patients with mitral stenosis or predominant mitral stenosis underwent open heart mitral commissurotomy at the San Camillo Hospital between May 1969 and May 1975; mitral annuloplasty was performed on 71 patients, subvalvular apparatus correction on 43. The operative mortality rate was 0,7% (no deaths among the last 220 patients). Early results, evaluated from intraoperative data, clinical course, acoustic and polygraphic postoperative findings, were good in 228 patients (80%), fairly good in 41 (14%), bad in 17 (6%).

Adolescent↗