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Biomedical subjects

F Galland

Publications and source records attributed to F Galland.

At least 73 records · Page 4Linked to original sources

[Indications and radiological measurements in the evaluation of pulmonary artery hypertension].

Different radiologic indexes and measurements proposed in the evaluation of pulmonary artery hypertensión (PAH) were reviewed. The postero-anterior chest roentgenograms of 250 subjects were studied. In all cases the pulmonary artery pressure was known from cardiac catheterization. The diameter of the right pulmonary artery was larger than 1.7 mm. in 45% of cases with PAH. The pulmonary-lobar-transverse-thoracic index (PL/T) was abnormal (+38%) in 74% of cases with PAH, and normal in cases with increased pulmonary flow. The index of Ozawa, distance between the midline and the more prominent portion of the pulmonary arch, related to the transverse diameter of the left hemithorax overestimated the mean pulmonary pressure when normal and underestimated the same with PAH. A new index is described. The relation of the right pulmonary artery with the transverse diameter of the hemithorax on the same side (r/h index). It was abnormal in 24% of the cases with PAH and it was always normal in cases with increased pulmonary flow. The more sensitive and specific measurement seems to be the PL/T index.

Adolescent↗

[Obstructive pulmonary emphysema. Evolution of various parameters of pulmonary function and its correlation].

A follow-up study was carried on in a series of 20 patients with chronic obstructive pulmonary disease. The parameters analyzed were forced expiratory volume in the first second (FEV1), maximum voluntary ventilation (MVV), forced expiratory flow (FEF), vital capacity (VC), and diffusing capacity of lung (DL). Considering the importance of the parameter changes observed, each of these parameters were divided in three groups. The period of observation was of two and a half years in 9 patients, and between two years and seven months to four years in 11 patients. The follow-up was characterized by stability of the parameters in cases with the greatest degree of changes, and a definite deterioration of the parameter values in patients with minor degree of basal changes. It was observed an excellent correlation between FEV1 and MVV and FEF. As to CV and DL, the relationship was only good. These findings lead us to believe that MVV and FEF values can be predicted about from the FEV1 results.

Carbon Dioxide↗

[Palindromic rheumatism. Immunologic survey and study of development in 43 cases].

43 patients (18 females, 25 males) presenting palindromic rheumatism were given follow-up examinations after a mean lapse of 14.75 years. 16 subjects still presented palindromic rheumatism and of these six showed complete remission. 27 patients had developed chronic inflammatory rheumatism after seven years (mean value) of palindromic rheumatism, but resolution of PR was seen in four cases. Male predominance was more marked in the palindromic subgroup (PAL) but was also seen in the subgroup of subjects who had developed PR (PAL-PR). Laboratory tests demonstrated a constant homogeneous increase in immunoglobulins (notable IgAs) and in the T4/T8 ratio in the PAL and PAL-PR subgroups. Rheumatoid serodiagnostic tests were positive significantly more frequently in the PAL-PR subgroup, which also comprised a high proportion of cases of erosive arthritis. Overall the frequency of HLA-DR 4 antigen did not increase in the subjects studied. Subjects in the PAL subgroup (cf. PAL-PR subgroup) were characterized by a twofold increase in frequency of DR 5 antigen, with a relative risk of 3.5 to 4.5, a significant increase in B35 and B5 and a clear decrease in B12.

Adult↗