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Biomedical subjects

F Furlanello

Publications and source records attributed to F Furlanello.

At least 109 records · Page 6Linked to original sources
PubMed1976

[Tachycardia caused by sinus-node and atrial re-entry with associated depression of A-V conduction].

The authors report two clinical cases (one with WPW syndrome) of paroxysmal supraventricular tachycardia caused, in one case, by sino-atrial node or perisinusal nodal tissue re-entrance and in the other case by re-entry in the lower atrium and the high part of the A-V node junction. Both present A-V node Wenckebach periodism, which can be distinct from reciprocating tachycardias, through an anomalous pathway or within the A-V node, which have a typical A-V conduction in the ratio of one to one. But A-V node Wenckebach periodism makes it hard to differentiate between reciprocating and ectopic atrial tachycardias, as the latter often has an A-V block. The effects of two antiarrhythmic drugs (Verapamil, Amiodarone) on echo-zone duration, on initiation and on prophylactic long-term treatment of paroxysmal tachycardias are also reported and discussed.

Aged↗
PubMed1976

[Effects of verapamil on sinusal function and on atrioventricular conduction along normal and abnormal pathways, in patients with pre-existing troubles of excitation conduction (author's transl)].

Effects of verapamil (5 mg i.v.) on excitation conduction in 20 patients who already had a basic alteration (7 with ventricular pre-excitation syndrome) were studied by His electrogram, during spontaneous sinusal rhythm and atrial electrostimulation in increasing frequencies. In 4 cases, a test crossed with atropine was carried out. The effects of the drug on the effective refractory period of the A-V node and the anomalous tract in 3 patients with W.P.W. syndrome of Kent's bundle were studied. The effects were: no significant modifications in the sinusal frequency; increase in the corrected preautomatic pause only in cases with sick sinus node syndrome and serious basic compromise of the sinus node function; slowing down of A-V conduction in the supra-hisian area and increase of the effective refractory period of the A-V node; no modification of the intra-atrial conduction, or the under-hisian and intraventricular A-V conduction; uneven slowing down of conduction along the anomalous tract of the pre-excitation syndrome of the James bundle; modification of the effective refractory period of the anomalous tract of the Kent bundle type, variable from case to case. On the basis of the electrophysiological properties, the possibilities and limits of use of the drug in sick sinud node syndrome in the common supraventricular paroxymal tachycardias, in atrial fibrillation, atrial flutter and arrhythmias of the ventricular pre-excitation syndrome are emphasized.

Adult↗
PubMed1975

[Venous infusion of nerapamil in the treatment of refractory angina pectoris and arrhythmia due to associated electric instability].

The therapeutic effect of Verapamil in 45 patients with angina that had failed to respond to other drugs is described. Angina was distinguished in terms of its clinical and ECG features. Verapamil was administered i.v., usually in infusions of 10-250 mg/day over periods of hours or days; alternatively, direct injections of 2,5-5 mg were employed. The effect on arterial pressure is particularly stressed. In the great majority of cases, there was a marked improvement in the symptomatology and in arrhythmic changes arising during angina. The importance of the therapeutic effects of the drug is examined and its possible mechanisms of action are discussed.

Adult↗
PubMed1975

[Anti-arrhythmic therapy with verapamil by intravenous infusion].

Rapid and slow venous infusion of various doses of Verapamil in a mixed series of 185 cases of arrhythmia since 1968 is reported. Results and electrophysiological and ECG changes observed for each type of arrhythmia examined are considered separately: atrial fibrillation-flutter, supraventricular paroxystic tachycardia (atrial and/or junctional), and hyperkinetic ventricular arrhythmia. An association of i.v. Verapamil and a quinidine salt per os is suggested as an alternative to cardioversion in cases of recent atrial fibrillation-flutter. Results obtained in the treatment of arrhythmia due to electrical instability following angina and of angina following arrhythmia are also described. A study of His potentials as the premiss for using Verapamil in subjects with stimulus conductivity changes, including W.P.W. syndrome, is also reported. I.v. Verapamil was used in association with atrial and/or ventricular electrostimulation, and/or with electrical counter-shock in cases of arrhythmia (mostly supraventricular) that were especially refractory. Attention is drawn to the use of Verapamil in the control of arrhythmia after electrical cardioversion.

Adolescent↗
PubMed1975

[High-frequency electric stimulation of the atrium in treatment of supraventricular tachycardias and atrial flutter].

The authors report the results of rapid atrial stimulation in the treatment of 12 cases of junctional tachycardia (J.T.), 20 cases of atrial tachycardia (A.T.) and 43 cases of atrial flutter (A.F.). Sinus rhythm was restored in 91.6%, 70% and 60.4% of the cases for J.T., A.T. and A.F. respectively, either when pacing was discontinued or following a period of atrial fibrillation (from a few minutes to several hours). Fifteen per cent of the cases of A.T. and 25.5% of the cases of A.F. turned into stable atrial fibrillation with reduction of ventricular rate. The authors believe that this technique is a valuable alternative to D.C. countershock when medical treatment has proved ineffective and when countershock may be hazardous.

Adult↗