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Biomedical subjects

F Ferrero

Publications and source records attributed to F Ferrero.

At least 37 records · Page 2Linked to original sources
PubMed1997

Structure and protective capacity of tetanus and diphtheria antibodies produced during human pregnancy and transferred to new-born.

PROBLEM: The structure and protective activity of antibodies against tetanus (anti-T) and diphtheria (anti-D), produced during human pregnancy and transferred to new-born, was studied. METHOD: Antibody levels were measured by ELISA in non-pregnant women (control group), primiparae, and multiparae, and in their children. The proportion of symmetric and asymmetric IgG molecules was determined and their respective protective capacity evaluated. RESULTS: The quantity of asymmetric anti-T and anti-D antibodies in mothers at the time of delivery was roughly four- and three-fold that of the control group, respectively, dropping significantly 1 month later. A similar proportion of these antibodies was observed in the new-born. The lower neutralizing capacity of asymmetric molecules was demonstrated in vivo. CONCLUSION: Results show that during pregnancy there is a modulation of the immune response with an increase in the production of asymmetric molecules of lower protective capacity.

Adolescent↗
PubMed1996

Spectrographic differences between tracheal-esophageal and esophageal voice.

In order to evaluate the results of voice and speech rehabilitation after total laryngectomy some acoustic parameters (fundamental frequency, waveform perturbation) were examined in 18 total laryngectomy patients. Eight of these subjects had previously been surgically rehabilitated with a tracheal-esophageal phonatory valve while 10 had been submitted to esophageal speech rehabilitation. Analysis of results has shown that tracheal-esophageal voices are more likely to provide a stable fundamental frequency; there is also a tendency toward more clearly defined harmonics; jitter and shimmer are more similar to the values of normal subjects compared with those observed in esophageal speech. Such results seem to depend on a more regular vibration pattern in the pharyngeal-esophageal segment, due to the more efficient expiratory flow in tracheal-esophageal speech. Moreover we were able to demonstrate a correlation between the objective parameters evaluated and the subjective score on speech acceptability.

Humans↗
PubMed1995

[Epidemiology of violence in psychiatry].

An overview of the literature indicates that violence in psychiatry is caused by a minority of patients. Despite the lack of precise definition, between 3 and 10% of patients shows an assaultive behaviour, at least once during the hospitalisation, but, fortunately, injuries are exceptional. The authors present some results of a research project evaluating the frequency and the cost of violence.

Cross-Sectional Studies↗
PubMed1991

[15 cases of femoro-popliteal bypass with PTFE graft].

The authors report their clinical experience of 15 cases of femoro-popliteal by-pass with PTFE; all patients underwent postoperative anti-platelet therapy, in 8 cases with ASA and dipyridamole, in 7 with indobufene in accordance with a double blind randomized work. The Authors report the results of a one year follow-up. They deal with patency duration results and tolerance of pharmacological treatment.

Blood Vessel Prosthesis↗
PubMed1990

Expressed emotion and first-admission schizophrenia. Nine-month follow-up in a French cultural environment.

A study of 36 French-speaking families in Geneva identified 66% of high-EE household. At nine-month follow-up, the relapse rate for the high-EE group (33%) was significantly higher than for the low-EE group (0%). These results seem to confirm the relevance of EE as predictor of relapse. However, in our sample, it appears that one component of EE, critical comments, was principally responsible for the prognostic validity.

Adolescent↗
PubMed1990

[Extra-anatomical bypasses: axillofemoral and femorofemoral. Indications and results].

Indications for a unilateral or bilateral axillofemoral and femorofemoral bypass, are presented. Our experience in 48 patients with axillofemoral and femorofemoral form the basis of this report. Indications for these extended bypasses included suppurative growing infection and obliterated common and profunda femoris arteries. These procedures were rapidly performed in critically ill patients. One patient died of recurrent artoduodenal hemorrhage three days following successful axillofemoral bypass. The other patients enjoyed patent grafts for variable periods, although some of them successfully underwent a declotting procedure.

Aged↗
PubMed1990

[Popliteal aneurysm. Our experience in 65 cases].

Fifty patients with 65 popliteal aneurysms underwent reconstructive procedures (mean age 64). Atherosclerosis is almost the exclusive cause of popliteal aneurysms. Most of the cases showed an acute ischemia, while he others were asymptomatic or presented a complication of venous occlusion or neural compression. Numerous cases were found incidentally at amputations (these were not included). The best operational method is ligation of the aneurysm sometimes with partial resection and autologous venous graft bypass. The immediate results were excellent in all cases, loss of limb was observed in only three.

Aged↗
PubMed1989

[Anxiety neuroses: uncertainty of epidemiology].

The author investigates the evolution of relationships between epidemiology and diagnostic classifications. The scope of neurotic disorders is considerably broader than the scope of anxiety disorders in the DSM IIIR, despite the introduction of new concepts such as panic disorder. Epidemiological studies require today diagnostic instruments based on structured interviews. They provide more homogeneous groups of patients. The recognition of the importance of the anxiety disorder's prevalence is a prerequisite for improving both therapeutic and prophylactic interventions.

Anxiety Disorders↗
PubMed1988

[Review of genetic studies of the nosology of anxiety disorders].

This paper reviews some of the important studies on the genetic aspects of anxiety, based on clinical, family and twin studies. Well-known methodological difficulties characteristic of earlier studies are at this time partly resolved. Researchers use specific criteria for defining subcategories of anxiety disorders. These are being applied in large epidemiological family studies and national twin registers. The part played by genetic or environmental factors varies greatly according to diagnostic sub-category. A genetic influence seems important for panic disorders and agoraphobia, but not for generalized anxiety disorder. A validation of these sub-categories could be obtained from discoveries of molecular genetics.

Anxiety Disorders↗