The involutive restriction of renal function, of thirst, and loss of body fluid reduce the adaptability of the electrolyte- and fluid metabolism in the geriatric patient. The causes of hydromineral emergencies involving the elderly are discussed. It is explained how, in the geriatric patient, the rapid disturbance of fluid metabolism can frequently pose a more serious threat to life than the underlying pathology, and how awareness of this problem and its rapid resolution can often save the geriatric patient's life.

Adaptation, Biological↗

PubMedDate not supplied

[Relations between disordered exocrine pancreas function, alcohol consumption and age in alcoholics].

During clinical withdrawal treatment, a disturbed exocrine pancreas function was found in 28 per cent of 72 alcohol addicts, which occurred in connection with an alcohol-induced pancreatitis. The clinical course was mainly quiescent. Altered bicarbonate concentrations and enzyme dissociations were found as a result of the secretin pancreozymin test. In alcohol addicts, the maximum activity of the amylase output was reached as early as 20 minutes and that of bicarbonate, trypsin and chemotrypsin not until 40 minutes post stimulationem. The sums of the logarithmically transformed 40-minute output of bicarbonate, amylase and trypsin displayed significant differences between the alcohol-addict and control groups. The degree of severity of the disturbed exocrine pancreas function was essentially a function of the daily amount of alcohol taken by the addict and of the age of the patient. The dysfunction was most evident in the 30-to-50-year-old patients. Chronic consumption of alcohol is assumed to give rise to a selective effect on the hydro-kinetic and ecbolic pancreas function.

Adolescent↗

PubMedDate not supplied

[Involutional peculiarities of digestion and resorption--deduction of preventive and therapeutic needs].

First indication of an age-related alteration of digestive tract can be proseed an age of fourty. In healthy elderly man functional capacity of nutritions is lowered. Normally the digestive capacity will be sufficient provided a reasonable nourishment. Usually the intestinal absorptive capacity tends to decrease in the elderly. But following delayed intestinal transit of nutritients absorption to a certain degree can occur sufficiently. Considering the nutrition of elderly people recommendations are given.

Age Factors↗

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[Exsiccosis as an emergency condition in the aged].

The involutive restriction of the renal function and of the thirst and the reduction of body water also diminished the range of efficacy and possibility for adaptation of the water metabolism of old people. Under geriatric aspects the causes for the senile exsiccosis are discussed. It is found that in old patients the quicker metabolism imbalance means a stronger threat of life that the disease itself. Often the consideration of this problem in much cases of diseases can save the life of the old patient.

Adipose Tissue↗

PubMedDate not supplied

[Status and role of nursing in the medical care process].

Explore the source record for details and available documents.

Communism↗

PubMedDate not supplied

[Therapy of pancreatitis and excretory pancreatic insufficiency in elderly patients].

Early active conservative therapy is of decisive importance for the prognosis of acute pancreatitis. Irrespective of the age of the patient a standardized basic therapy has to be adopted, but even in the old patient elective surgical treatment should not be regarded as "ultima ratio". As a matter of principle, conservative measures should first be taken to treat chronic pancreatitis. Surgery will be indicated in the presence of resistance of therapy or complications irrespective of the patient's age. Insufficiency of the excretory pancreatic function in old age may be asymptomatic, whereas gastrointestinal complaints can be improved or eliminated by enzyme substitution. But if the gastrointestinal symptoms complex in the elderly cannot be influenced by the administration of pancreatic enzyme, it would not be serious to dismiss such symptoms as consequences of the process of ageing.

Aged↗

PubMedDate not supplied

[Simulation of the effect of biologically active substances in models].

The results obtained from historadioautographic examinations of the epithelium of the small intestine of rats under the action of procaine served as a basis for examining the proliferative system by using a model. The following results have been obtained through computerized simulation: 1. The maximum life-time of the enterocytes is prolonged at constant villous height, which means that on average the villous is studded with older cells than normally. 2. The prolonged time of generation of the proliferatively active cryptic epithelial cells calls for a pronounced reduction in the pool of reserve cells (cells in the G0 phase, non-growth fraction), i.e. for their activation in order to realize the system characteristics described under 1. 3. The condition of the system induced by procaine may be compared, in its changed tendency, neither to the changing tendencies during aging nor to those under pathological conditions. It is rather a new condition that is being produced and which is characterized, inter alia, by the characteristics described under 1 and 2.

Aging↗

PubMedDate not supplied

[Senile changes in the resorption and elimination processes and their importance in pharmacotherapy].

On the basis of experimental and theoretical examinations the senile changes in man's absorbent system and renal excretory function were analysed. It was found that intestinal absorption and summary elimination are delayed with advancing years. Practical consequences with regard to dosage and dosage intervals can be derived for geriatric pharmacotherapy. By the example of selected groups of drugs the necessity for revised dosage instructions and application intervals in old age is explained.

Aged↗

PubMedDate not supplied

[Iatrogenic disorders of the pancreas in old age].

Besides the effects of iatrogenic and environmental factors on the pancreas, the article describes the effects of senile changes on the morphology and function of the excretory pancreas. The article pays particular attention to pancreatic trauma and post-inflammatory conditions, postoperative syndromes, the endoscopic retrograde cholangiography of the pancreas, the effects of alcohol on the pancreas, and rare pancreas conditions, which, in old age, may lead to morbid functional restrictions.

Aging↗