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Biomedical subjects

F Debruyne

Publications and source records attributed to F Debruyne.

99 records · Page 6Linked to original sources
PubMed1980

[Normal values in brain stem electric response audiometry (BERA)].

The normal values in brainstem electric response audiometry (BERA) were studied. A description is given of the latencies and amplitudes of the normal response. The effects of (1) the intensity of the stimulus, (2) the stimulation rate, and (3) the use of a sedative were investigated. It seems that the transmission time P1-P5 is significantly longer (+/- 0.25 msec) in men than in women.

Audiometry↗
PubMed1979

Cold knife optical urethrotomy.

Cold knife optical urethrotomy with the Sachse urethrotome was used in 44 patients with urethral strictures. Appraisal if the results, after a mean follow-up of fourteen months, showed 77.3 per cent success rate regarding urine flow rates and 81.8 per cent regarding subjective response of the patient.

Adult↗
PubMedDate not supplied

One-year follow-up after tympanostomy tube insertion for recurrent acute otitis media.

In a prospective study, 126 children were followed for 1 year after the placement of tympanostomy tubes especially for recurrent acute otitis media. About 7 in 10 children remained free of middle ear infection and 1 in 10 showed frequent (i.e. 3 or more) episodes of otorrhea during the follow-up period. However, the most conclusive observation was that the otorrhea episodes were not equally distributed over the different ages: they were markedly more frequent in the group younger then 2 years old, although the prestudy infection rate was similar in all age groups. Furthermore, the incidence of middle ear infection was positively correlated with upper respiratory infection but not with other variables such as prestudy spontaneous perforations, contents of the middle ear, presence of the tube at the end of the study, and swimming habits. It seems that middle ear infection with ventilation tubes in place is influenced by age and upper respiratory infection as it is for acute otitis media in the population as a whole.

Acute Disease↗
PubMedDate not supplied

The therapeutic approach to intrathoracic metastases of non-seminomatous testicular tumour.

Before the era of chemotherapy an extensively metastasized non-seminomatous testicular tumour was nearly always fatal. Only 10 cases of spontaneous regression of thoracic metastasis have been reported. With chemotherapy, a much better outlook has been achieved, however, in 10% of the cases, chemotherapy resistant thoracic masses remain after treatment. In 70 to 80% of those cases with normal tumour markers, mature teratoma is found. In this paper, three patients with non-seminomatous testicular tumour and thoracic opacities resistant to conservative treatment are reported. One patient showed a complete disappearance of 9 out of 10 thoracic opacities 6 months after a short chemotherapy course, which had seemed to be ineffective. After a short period of reduction, the remaining opacity demonstrated continued tumour growth with a significantly longer tumour doubling time. The other two patients showed enlarged thoracic opacities despite combination chemotherapy and normal tumour marker levels. At the time of thoracotomy and complete surgical resection of the tumours all patients had normal tumour marker levels. Mature teratoma without genuine malignant cells was found microscopically. At this time all patients are free of metastases, 18, 3.5 and 2 year post thoracotomy. We suggest complete extirpation of the chemotherapy resistant lesions because, mature teratoma may give rise to compression and because in the cases with notwithstanding normalization of tumour markers and active tumour histology has to be obtained to restart combination chemotherapy.

Adult↗