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Biomedical subjects

F Christ

Publications and source records attributed to F Christ.

At least 91 records · Page 5Linked to original sources
PubMed1987

[Diagnosis of sarcoidosis using MR tomography].

One hundred and thirty-three patients with lymph node enlargement from various causes were examined by MR tomography, using 0.5 and 1.5 Tesla. Amongst these, there were 27 patients with chronically enlarged lymph nodes and histologically confirmed sarcoidosis; these showed characteristic T1 intervals. Enlarged lymph nodes due to chronic inflammatory conditions can be differentiated from lymph nodes with malignant lymphoma, or from lymph node metastases from carcinomas. Although there are problems with the determination of relaxation times on MR tomography, this may be a valuable method for the differential diagnosis of sarcoid.

Adult↗
PubMed1987

[Circulatory distribution of intravenously injected metallic mercury].

The mode of distribution and sites of deposition of mercury are discussed on the basis of the example of a 21-year old female nurse who had injected 4.5 ml of metallic mercury into her left cubital vein with suicidal intent, the findings being compared with the reports by 11 other authors. In particular, the influence of gravity on the distribution in the organism is emphasised. The proof of the decrease of an intrapulmonarily deposited amount of mercury within the observation period of 14 months furnishes ample evidence of the importance of a chronic absorptive mercury intoxication.

Adult↗
PubMed1987

[Quantifying aortic valve insufficiency by digital subtraction aortography].

The purpose of this study was to assess the contribution of digital subtraction angiography (DSA) to the quantification of aortic valve regurgitation in 21 patients undergoing heart catheterization. The digital image subtraction was used for densitometric evaluation. The regurgitation was derived from the distribution of contrast volumes during diastole in aortic and left ventricular "regions of interest". DSA-measurements were compared with results of conventional cineangiography. Results showed the following correlation between DSA measurements and cineangiographic estimates (grades I-III): regurgitation 1.7-9.8% in grade I (n = 11), 8.9-22.3% in grade II (n = 5), 31.7 and 32.5% in grade II-III (n = 2), 37-42.4% in grade III (n = 3). DSA and digital densitometry seem to be valuable methods for the quantification of regurgitation. Concerning quantitative measurements in left heart catheterization the digital subtraction aortography is superior to conventional cineangiography and will be helpful to characterize patients with aortic regurgitation more completely.

Adult↗
PubMed1986

[Sonographic diagnosis of arterial occlusive disease].

In 32 patients presenting symptoms of arterial occlusive disease, 50 lower limbs were examined both by ultrasonography and angiography (DSA). Sonography was performed using a 5.0 MHz real-time scanner; common femoral, superficial femoral and deep femoral arteries were visualized continuously in whole length. In 84% both the results from sonography and digital subtraction angiography verified or excluded arterial occlusion. Since lack of pulsation is the ultrasonic criterion of occlusion, real-time ultrasound does not differentiate between haemodynamically effective high-grade stenosis and total occlusion.

Aged↗
PubMed1986

[Significance of the urethral pressure profile in the diagnosis of urethral diverticulum].

Diverticulum of the urethra was diagnosed by us in ten women during the past two years. In nine of these, the urethral pressure profile showed a characteristic course: In the region of the diverticulum--confirmed subsequently by radiography--a drop in pressure was recorded as a sign of damage to the wall. The value and importance of the individual steps in the diagnosis of diverticula are discussed. Suspicion of a diverticulum in the urethra can be raised by careful anamnesis and by means of the urethral pressure profile. This suspicion can be safely confirmed or refuted via urethrography using the double-balloon catheter.

Adult↗
PubMed1986

[Videodensitometric determination of relative blood regurgitation volume in aortic valve insufficiency].

A simple video densitometric method based on the indicator distribution principle in the region of interest permits the determination of the relative amount of regurgitation between the ascending aorta and the left ventricle in cases of aortic valve insufficiency. The experimental basis and early clinical measurements are described and are compared with the more conventional methods of cine angiography and radionuclide ventriculography.

Adult↗
PubMed1986

[Differential analysis of ventricular contraction using digital subtraction angiography].

One hundred and thirty-six patients with various cardiac abnormalities that had been diagnosed by standard methods, were examined by I-V DSA; images of the left and right ventricles during a representative cardiac cycle were submitted to amplitude and phase analysis, using a Fourier transformation. Temporal differentiation of ventricular function was derived from the best available right anterior oblique projection; the amplitude of cardiac movement of abnormal areas in the myocardium were obtained from a grey scale or colour coding at a fixed point. Comparison with a control group of 35 individuals showed the following pathological findings: hypokinetic segments (33 cases) showed delay, dyskinesias (20 cases) showed complete separation of maximal phases, frequently with a double peak in the phase histogram; disturbances of cardiac rhythm (14 cases) showed atypical localisation of initiation of contraction: in Wolfe-Parkinson-White syndrome this is basal-anterior, in left bundle branch block and VVI stimulation it is apical inferior; in hypertrophic obstructive cardiomyopathy (eight cases) it is postero-basal inferior with high, narrow peaks on the phase histogram. Differential phase analysis on I-V DSA enables one to define cardiac contraction in a simple manner.

Angiography↗
PubMed1986

[Intravenous DSA of the heart: functional studies of the left ventricle in coronary heart disease at rest and following stress].

Intravenous digital subtraction angiography (i.v. DSA) of the heart is performed for demonstration of the morphologic and functional peculiarities of the left heart chamber, especially the ejection fraction and regional wall motion abnormalities. Employment of both geometric and video densitometric computation techniques resulted in a good correlation with direct ventriculography (r = 0.945), video densitometry, however, with a tendency to values up to 10% higher. Comparative DSA studies during rest and following exercise in 25 patients with coronary heart disease were suitable to discover pathologic strain reactions of the myocardium in 4 cases, typically depending on angiographic findings of the coronary arteries. In this way a simple method for better estimation of a deficit in coronary blood supply and its functional impact on myocardial performance may become useful.

Angina Pectoris↗
PubMed1985

Changes in urethral closure pressure after radical hysterectomy for cervical cancer.

The behaviour of the urethral closure pressure at rest (UCP) both before and 14 days and 3 months after radical surgery for cervical cancer was examined. The results were compared with those of other authors. In contrast to the latter we were only able to establish a constant pressure drop in patients using a transurethral catheter at the time of the first postoperative measurement. Patients using a suprapubic catheter showed non-uniform postoperative UCP-changes. This pattern was comparable to that found after simple abdominal hysterectomy, performed for other reasons, in which a transurethral catheter had been in place for a maximum of 60 h. In contrast to our predecessors we were unable to confirm a causal relationship between surgical damage to the sympathetic system and postoperative falls in pressure, except after extremely radical surgery. The cause appears to be a complex process involving wound healing problems (edema, infection, scar formation and organ position changes) and direct traumatization of the urethra (transurethral catheter).

Female↗
PubMed1985

[Initial experiences with transvaginal sonography of the urethra and bladder within the scope of the diagnosis of incontinence].

Female urinary incontinence can be visualized only insufficiently be means of static methods such as the lateral cystourethrogram. Detailed information on physiology and morphology or pathological abnormalities can be gained only by means of dynamic methods, where transvaginal or transrectal sonography could become the method of choice. The essential advantages of this method over the conventional imaging methods are discussed.

Female↗
PubMed1985

[Morphometric and densitometric assessment of left ventricular function in the digital subtraction angiocardiogram].

The paper deals with the early clinical experience, using a new DSA installation with a specially programmed cardiological module. DSA provides very good contrast and special resolution and morphometric estimation of the ejection fraction and regional movement of the left ventricular myocardium derived from DSA. This is as good as the results of the left cardiogram. The significant advantage of DSA ist the ability to make a rapid and simple diagnosis. In addition, it is possible with densitometric methods to calculate ventricular volume curves and to provide phasic indications of the amplitude to contraction of the left ventricle. These investigations have so far proved valuable and provide new scope for the radiological evaluation of left ventricular function.

Absorptiometry, Photon↗
PubMed1985

Pelvimetry by digital radiography and its dosimetry.

Sonography is firmly established in obstetrics as the method of choice for the localization of fetus and placenta. However, for the determination of pelvic dimensions sonography does not suffice. Thus, for a few strictly selected indications conventional x-ray pelvimetry is used. This has the disadvantage of the relatively high radiation dose for the fetus and the maternal gonads. Since the introduction of digital radiography, there is the alternative of digital pelvimetry. We performed dosimetry comparing digital and conventional radiography with the new high amplifying screens (Quanta III, Dupont) using an ionization dosimeter and a wax phantom. The radiation dose of digital radiography was 24 mu Gy. This corresponds to about 15% of a comparable conventional exposure (177 mu Gy). A further advantage of digital radiography is a standardized and rapid exposure technique; furthermore pelvic dimensions can be measured directly. The disadvantages are the poorer spacial resolution and poor image quality in obese patients. Digital radiography because of its lower radiation dose is suitable for pelvimetry for special indications.

Computers↗
PubMed1984

[Pelvic bone angiomas].

Three patients were seen with angiomas of the pelvic bones; the radiological and clinical features are described and the literature reviewed. The patients had been observed for four to six years. The differential diagnosis includes infiltrating mesenchymal neoplasms and the histologically similar, but rare, Gorham-Stout syndrome. Recommended treatment is irradiation, which is effective up to a point.

Adult↗
PubMed1984

[Intrathoracic-extrapleural esophageal replacement with gastroplasty].

We carried out replacement of the oesophagus by transposing the stomach in 87 patients, 64 with carcinoma of the oesophagus. There is an immediate operative mortality of 20-30%, but this is followed by a relatively low morbidity, which is well demonstrated radiologically (stricture at the anastomosis, which can be mechanically dilated, about 22%; external fistula with a tendency to spontaneous closure about 25%; ectasia of the thoracic stomach, 15-25%). Average survival time is eight to ten months. There is a 24% risk of post-operative pulmonary oedema and daily chest x-rays are indicated.

Adult↗
PubMed1983

[Densitometry and fetal superficial cell count in the amniotic fluid for the determination of fetal lung maturity].

It was shown that a spectrophotometric investigation of the amniotic fluid for the determination of fetal lung maturity can be achieved with a photometer of the wave length 644 nm (CD) and 623 nm (HG) in conjunction with a count of superficial cells. In a small number of investigations the combination of spectrophotometry and fetal cell count is a sufficiently accurate method to determine fetal lung maturity.

Amniotic Fluid↗