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Biomedical subjects

F C Hugues

Publications and source records attributed to F C Hugues.

At least 73 records · Page 4Linked to original sources

[Use of sympathomimetics in the treatment of asthma].

There are many sympathomimetic products available in treatment of asthma, such as ephedrin, isoproterenol, orciprenalin, salbutamol, terbutalin..., used by oral or injectable route and spray. In the spray form, the sympathomimetic products have immediate and intense activity but the easiness of their use leads to a dose multiplication or overdose ineluctably, and thus involves cardiac and respiratory accidents which can be fatal. Their prescription should be slightly different according to the clinical type of asthma in the patient. On the other hand the oral sympathomimetic products are less inclined to overdose.

Albuterol↗

[Asthma and propranolol].

The authors report the results of a study of propranolol perfused intravenously at a dose of 1 mcg/kg/mn during 30 mn to 50 asthmatic patients. The VC decreased by 8.3 and by 10.9% in the middle and at the end of the perfusion. The FEV1 decreased by 18.3 and 23% concomitantly. Classifying patients in 4 groups according to the clinical severeness of the asthma showed that the response to propranolol increased with that severenesse. Exploration of obstructive bronchopneumopathies by propranolol provided valuable data or the differential diagnosis of asthma and chronic bronchitis.

Adult↗

[Evaluation of an analgesic activity in man: thermodolorimetery].

The authors propose an experimental technique which makes possible the evaluation in man of the activity of analgesic or anti-inflammatory medications. The principle of thermodolorimetre threshold of painful thermic sensitivity (S.S.T.D. in the french text) which is stable over a period of time in a given individual receiving a placebo but which varies in a significant fashion in groups treated with a medication belonging to one of the two classifications studied.

Administration, Oral↗