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Biomedical subjects

F Bloch

Publications and source records attributed to F Bloch.

At least 73 records · Page 4Linked to original sources

[Does the hepatitis of secondary syphilis exist? Two cases (author's transl)].

Two patients are presented as new cases of secondary syphilitic hepatitis. The closely resemble descriptions in the literature with the same clinical and laboratory "profile" and the same course spectaculary influenced by anti-syphilitic penicillin therapy. The presence of treponemes in the liver, which would definitely confirm the diagnosis, was not demonstrated. This is a particularly important diagnosis, which should not be missed since it leads to treatment of fundamental importance to the patient's future.

Adult↗

[Lesions of the myenterix plexuses in idiopathic chronic intestinal pseudo-obstruction and in certain general diseases].

Recent observation of a case of idiopathic chronic intestinal pseudo-obstruction and the relationship sometimes suggested in this context with certain systemic diseases, such as scleroderma, led the authors to compare the changes seen in the myenteric plexuses in these different groups of disorders. The intramural plexuses were studied using the technique of B. Smith, in thick frozen section parallel to the lumen and stained using Bielchowsky's method. Plexus innervation was normal in a case of digestive amyloidosis and a case of myxoedema. There were secondary changes in the plexuses in scleroderma. The lesions were very different in our case of idiopathic chronic intestinal pseudo-obstruction (marked decrease in the number of neurones with degenerative changes in the neurones and dendrites, marked schwannosis). A decrease in the number of neurones was seen in a case of severe diabetes. Various mechanisms are discussed. These cases emphasize the great value of B. Smith's technique in the fine study of the intramural plexus innervation of the digestive wall.

Adult↗

[Acalculous cholangitis and cholecystitis in two AIDS patients].

Acalculous cholangitis and cholecystitis may occur in the course of AIDS. The symptoms are always the same: pain in the right upper quadrant, fever, nausea, vomiting, anorexia and diarrhoea, associated with biochemical signs of cholestasis, often without jaundice. Morphological explorations show thickening of the gallbladder wall and dilatation of the extrahepatic bile ducts, sometimes associated with stenosis of the major duodenal papilla and dilatation of the intrahepatic bile ducts.

Acquired Immunodeficiency Syndrome↗

[Care of chronically ill geriatric patients with the cooperation of relatives].

In the first stage of the project "assistance of relatives for the care of chronically ill people" in context of the National Research Programme No 8 (Economy and efficacy of the Swiss Health System) a representative random sample of elderly longterm patients was arranged in Basle and the situation regarding their relatives investigated. Altogether 473 relatives were contacted. Finally 343 interviews with next-of-kin were held and as many questionnaires filled out. The main aim of the questioning in the first part of the study was to know who would be able to participate in the care at the hospital on a part-time basis. Basing on the results, it may be presumed that about 30% of the relatives of chronically ill patients who have regular personal contact with them are ready and willing to participate actively in a co-operative model set-up of a nursing institution. In the second stage the way should be paved for the management of a pilot-station. During the research programme between 1983 and 1985, the model-idea should be examined for its practicability. Afterwards it can be judged if the basic idea of the project evidences a real progress or remains a social-medical utopia.

Aged↗

[Spontaneous pneumoperitoneum in scleroderma].

A spontaneous and asymptomatic pneumoperitoneum was observed in two women presenting with pseudoileus resulting from severe gastrointestinal involvement in progressive systemic sclerosis. In the first case, pneumoperitoneum was associated with pneumatosis cystoides intestinalis and remained unchanged during 3 years. As obstruction resisted to medical management, surgery was performed; however at laparotomy neither perforation nor obstruction of the bowel could be found; the patient died during the postoperative course. In the second case, pneumoperitoneum disappeared after medical management of low-grade intestinal ileus but the patient died 6 months later because of cardiac failure. Autopsy revealed major distention of the bowel but failed to show any signs of perforation. These findings show that, in progressive systemic sclerosis, pneumoperitoneum can occur in the absence of digestive perforation and that surgery is not required. However this complication seems to carry a very poor prognosis.

Aged↗

["Dysphagia lusoria". Physiopathological discussion apropos of a clinical case].

We report the observation of a patient suffering from dysphagia lusoria, a dysphagia caused by an anomalous form of the right subclavian artery. The diagnosis was confirmed by aortic arch angiography and cine-oesophagogram. Oesophageal manometric study revealed segmental hypoperistalsis and anti-peristalsis. Dysphagia disappeared with cisapride. This observation suggests that dysphagia lusoria is caused by oesophageal motility disorders and not by vascular compression.

Angiography↗