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Biomedical subjects

F Bloch

Publications and source records attributed to F Bloch.

At least 37 records · Page 2Linked to original sources

Effects of professional affiliation on group therapists' confidentiality attitudes and behaviors.

This study examines the influence of group therapists' professional characteristics on their attitudes and practices regarding confidentiality. Eighty-three highly experienced and well-trained group therapy providers representing the fields of psychiatry, psychology, and social work completed a survey questionnaire inquiring into their confidentiality practices. Although there is considerable consensus between medical and nonmedical practitioners on the issues addressed, there are also interesting differences and trends. Implications of the findings for clinical practice, ethics training, and confidentiality legislation are addressed.

Adult↗

Guarding confidentiality in clinical groups: the therapist's dilemma.

This study examines the confidentiality practices of highly experienced, well-trained group psychotherapists. A provocative finding was that practitioners rarely inform prospective clients of confidentiality limitations. Their reluctance to do so appears to be based upon the belief that it might discourage persons from entering treatment, as well as having negative ramifications for the therapeutic process (e.g., members may be less likely to talk about unprotected topics). The prevalence and content of breaches in confidentiality are explored. Ethical, legal, clinical, and educational implications of these and other findings are addressed. Research recommendations are offered.

Adult↗

Spontaneous peritonitis in cirrhotic hospital in-patients: retrospective analysis of 101 cases.

One hundred and one patients with cirrhosis resulting from alcohol abuse, admitted to Broussais University Hospital, Paris, between January, 1986 and December, 1989 were assessed for infection of the ascitic fluid using clinical and cytobacteriological criteria. All of 46 patients (45.5%) with clinical signs and symptoms of peritonitis had an ascitic fluid polymorphonuclear (PMN) count > 250 cells/mm3. Bacteria could be isolated from the ascitic fluid of 23 patients (50%). Twenty-six bacterial strains were isolated (there was more than one strain in two samples). Escherichia coli was found in 14 cases. It is noteworthy that no anaerobes were grown. Mortality, biochemical parameters and clinical features correlated significantly with an ascitic fluid PMN count > 250 cells/mm3. High mortality correlated with a PMN count > 1000 cells/mm3 (70% vs. 33%).

Ascitic Fluid↗

[Collagenous colitis: a new case of exudative enteropathy].

Collagenous colitis with intestinal protein loss was discovered in a sixty-six year-old female who presented with recurrent and prolonged diarrhea associated with hypoprotidemia, hypoalbuminemia, and increased clearance of alpha-1-antitrypsin. Histologic lesions of collagenous colitis were found during each episode of diarrhea. Biological and histological examinations were normal during the remission phases. Intestinal protein loss appeared to be due to collagenous colitis because of the parallel course of the clinical, biological and histological signs, and because no other cause had been discovered. The possibility of protein exudation, probably secondary to the extent of the epithelial detachment, could be an additional argument for the inflammatory etiology of collagenous colitis.

Aged↗

[Hemorrhagic gastro-duodenal ulcers. In which cases should emergency surgery be performed?].

From January 1983 to December 1987, 127 patients with bleeding peptic ulcer were admitted to hospital. The mean age of the 85 males was 57 years and 72 years for 42 females. All but four of the patients were managed medically after emergency endoscopy. Twenty-seven patients required surgical operations (21.2%): seven for cataclysmic haemorrhage, eight for persistent haemorrhage, twelve for recurrent bleeding. An analysis of factors leading to the necessity of surgical haemostasis was undertaken by considering the clinical status, endoscopic findings and laboratory results. The size of the ulcer (greater than 2 cm) was the most significant parameter (less than 0.01). Five other criteria (rectal bleeding) shock, endoscopic signs of recent haemorrhage, gastric or duodenal posterior ulcer) were also significant (p less than 0.05). Considering the gravity of these patients (six deaths among twenty-seven), clinical trials in bleeding peptic ulcer disease should only include patients in the high risk group.

Adult↗

Blood viscosity and sensorineural hearing loss.

Two groups of 33 subjects each, one experimental and one control, matched one-to-one for age and occupation, were chosen from a large number of subjects who were covered by special insurance for annual medical control at our hospital. The periodical checkups included cardiovascular, nervous, and renal systems, as well as vision and hearing. In addition routine blood tests, including whole blood viscosity, were also performed. The experimental group consisted of subjects in whom a bilateral, slight, and unexplained sensorineural loss of hearing was detected in the routine audiological testing, without any known reason. In the control group, the routine hearing tests demonstrated normal hearing. The differences between the two groups were statistically significant in pure-tone threshold level and in speech discrimination score, when the test was performed at a -5dB signal-to-noise ratio. The results of the vestibular tests were normal in both groups. Hematocrit and whole blood viscosity were slightly but significantly higher in the experimental group if compared with the control group. The number of subjects with abnormal whole blood viscosity results was higher in the experimental group. The whole blood viscosity as the etiological factor responsible for the hearing deterioration is described.

Adult↗

[Colonoscopic surveillance of patients operated on in colorectal cancer. Retrospective evaluation of 269 tests in 125 patients].

The ideal frequency of endoscopic surveillance of patients operated on for colorectal cancer is not known. We report our experience of colonoscopic follow up of 125 patients after excision of a colorectal cancer. The median interval between resection and the first check colonoscopy was 12 months. The median duration of follow-up was 28 months (range: 3 months to 10 years). 269 colonoscopies allowed diagnosis of 8 anastomotic recurrences within a median delay of 21 months after surgery (range: 3 months to 5 years). In 6 of these patients, the recurrence was clinically suspected. In 2 patients, it was asymptomatic and was discovered on systematic colonoscopy. Potentially curative surgery was only possible in 1 case. Follow up colonoscopies also allowed excision of 113 adenomatous polyps in 39 patients and the discovery of 4 new invasive cancers within a median delay of 7.4 years after excision of the first cancer. Due to the disappointing value of colonoscopy in the detection of anastomotic recurrences and the propensity of the remaining colon to develop new polyps, in the absence of a comparative trial, we arbitrarily adopted a follow up rhythm based on early post-operative colonoscopy (3 months post-surgery) and then yearly for the first 2 years. Further follow-up was similar to that adopted for patients with a past history of endoscopic polypectomy.

Aged↗

Morphometric study of colonic biopsies: a new method of estimating inflammatory diseases.

In this study, colonic biopsy specimens from 87 subjects (37 men and 50 women; mean age 51 +/- 14 years) were investigated by a new method of quantitation morphometric analysis. Subjects were classified in 3 groups: I, control group (25 cases); II, constipation and/or abdominal pain (36 cases); III, diarrhea (26 cases). All biopsy specimens were considered normal by both colonoscopic and microscopic observations. Morphometric analysis was performed with a specialized automated image processor. Complete analysis of 1 biopsy specimen required about 10 minutes. Glandular area showed no difference in the ascending, transverse, and descending colonic sites in the three groups. By contrast, the rectal glandular area was significantly larger than those from the 3 colonic sites in all groups (p less than 0.001). The mean cellular density in the control group was 172.7 +/- 24 nuclei/unit area of lamina propria at all biopsy sites. The cellular densities of groups II and III were significantly increased in the ascending colon as compared with the group I subjects (195.1 +/- 22.8, p less than 0.01 and 198.2 +/- 24.7 p less than 0.001, respectively). The cellular density in group III was significantly increased in the other sites as compared with group I (p less than 0.01). Morphometric analysis does provide a definition of the normal range of the lamina propria cellularity and can identify mild abnormalities in patients in whose both colonoscopy and conventional histologic interpretation have been considered as normal by experienced endoscopists and pathologists. A statistical increase in cellular density in groups of patients with clinical symptoms should be regarded as consistent with the concept of microscopic colitis and detectable by morphometry. Such a method reduces interobserver bias and permits objective comparison of groups.

Biopsy↗

[Morphometric analysis of systematic colonic biopsies].

Using an automatic image analysis processor we measured the cellular density of the lamina propria and the mean glandular area on biopsies issued from 10 normal patients. The microscopic image was automatically digitalized and filtered. The operator manually traced the perimeter of the mucosal glands. The mean nucleus number for a 32,000 microns2 chorionic area is 177 +/- 24. The mean glandular area is 51.2 +/- 2.9%. This method is fast (2 min by field) and reproducible. It can be proposed for the study of inflammatory conditions on systematic colonic biopsy material.

Biopsy↗