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Biomedical subjects

E Zingg

Publications and source records attributed to E Zingg.

At least 19 recordsLinked to original sources

Effects of nasal calcitonin on bone mineral density following parathyroidectomy in patients with primary hyperparathyroidism.

AIM: To investigate whether nasal salmon calcitonin (CT; 200 U/day) given in addition to calcium helps to restore the bone mass after parathyroidectomy (PTX) in patients with primary hyperparathyroidism (PHPT). METHODS: Twenty patients with PHPT were enrolled after successful PTX and received 1 g calcium per os daily for 1 year. They were randomly assigned either to nasal CT (CT group) or to no treatment. The bone mass was measured using dual-energy X-ray absorptiometry at multiple sites. RESULTS: Eight patients in each group completed the study. After 12 months, the bone mass increased significantly at whole-body level and at lumbar spine in both groups, increased at hip and epiphyses of tibia or radius in the CT group only, and did not change at diaphyses of tibia and radius in either group. CONCLUSIONS: Bone mass increases after PTX for PHPT in patients receiving oral calcium. CT may help to restore the bone mass at sites of the appendicular skeleton, where trabecular bone predominates.

Administration, Intranasal↗

[Disorders of bladder emptying following Burch colposuspension].

Forty patients with recurrence urinary stress incontinence (RUSI) were evaluated before and after Burch-colposuspension for voiding difficulties. Thirty-two (80%) patients were cured. Seven females developed an urge incontinence in the postoperative course, one female an urge plus stress incontinence. Residual urine was found in 6 of 7 patients with urge incontinence, in 5 patients a urinary tract infection. Four patients with urge incontinence after colposuspension were insulin dependent diabetics. In 18 patients residual urine was found in the postoperative course, only 6 patients were symptomatic with urge and urinary tract infection. We see a limited indication for Burch colposuspension in RUSI with reduction in vaginal mobility, detrusor hypocontractility, detrusor instability and in diseases predisposing to neurogenic bladder disorders.

Female↗

Exfoliative cytology after transurethral resection of superficial bladder tumours.

Fifty-one patients with predominantly superficial bladder tumours underwent prospective cytological examination at predetermined intervals following surgery in order to evaluate the prognostic reliability of bladder irrigation cytology. The results suggest that positive cytology 3 days after radical transurethral resection is a reliable indicator of incomplete resection or additional occult tumour foci. The implications for post-operative management and follow-up are discussed.

Follow-Up Studies↗

[Injuries of the membraneous urethra in children. 2 case reports and analysis of the literature].

Two cases of total disruption of the membraneous urethra in boys, 4 years of age, are reported. This experience and the literature suggest that a totally ruptured urethra should be realigned and the bladder drained by way of a suprapubic cystostomy. Urinary extravasation causes severe pelvic fibrosis with stricture or even closure of the urethra in children. The best procedure for similar adult cases, namely resection of the fibrosis and stricture with direct anastomosis of the intact urethra, is also best in pediatric cases.

Age Factors↗

Computerized tomography versus angiography in the staging of malignant renal neoplasm.

A comparative diagnostic study was carried out on 40 patients with pathologically proven renal malignancies which were staged both by angiography and CT. CT is more accurate than angiography for the detection of both perirenal and pararenal extension of the primary tumour (T-staging), and angiography is only slightly superior to CT in the evaluation of intravascular extension of the malignancy. The diagnostic performance of CT is clearly superior to angiography in detecting malignant lymphatic spread (L-staging) and distant metastases (M-staging). CT is, therefore, becoming the primary diagnostic approach for the staging of renal malignant tumours.

Adolescent↗

[Operative treatment of fractures of the penis (author's transl)].

5 cases of penile fracture are described. 2 patients were referred directly and received immediate surgical treatment. The corpus cavernosum was exposed and the tunica albuginea repaired with absorbable sutures. The other 3 patients were referred from 10 to 19 days after the initial injury. On admission 2 of the were experiencing deviation of the erect penis, one also had painful erection. They too were explored and the tunica albuginea sutured to correct the deformity. All 5 patients were treated post-operatively with a broadspectrum antibiotic, an anti-inflammatory agent and tranquilizers to prevent erections. Except for one patient with delayed wound healing there were no complications of the operation. The long-term results were good, all patients experiencing satisfactory straight erections.

Adult↗

Electroresection of the prostate in patients treated with heparin.

A comparison was made of blood loss under controlled heparinization and that occurring under normal conditions during electroresection of the prostate. Mean blood loss in patients treated with heparin amounted to 429.4 +/- 524.8 ml. and in the control group it was 391.8 +/- 451.4 ml. The difference is not significant. Therefore, a transurethral operation does not require interruption of anticoagulation therapy in cardiovascular patients.

Anticoagulants↗

[Computer tomography in the investigation of the suprarenal gland (author's transl)].

The computer tomographic appearances of pathological processes in the suprarenal were evaluated in 55 patients; consideration is given to individual normal variations and to various sources of error. It is concluded that adrenal computer tomography is the primary radiological means of diagnosis, particularly for diseases which deform the contours of the glands. Usually angiography is unnecessary. The structure and density of various adrenal masses, and their behaviour after intravenous contrast, usually provide a fairly accurate diagnosis. Nevertheless, exact evaluation of the findings can only be made in the clinical context and decisions regarding treatment should be the result of an interdisciplinary approach.

Adrenal Gland Neoplasms↗

[Computer tomography and retroperitoneal fibrosis (Ormond's disease) (author's transl)].

Four patients with retroperitoneal fibrosis (Ormond's disease) were examined by computer tomography; the appearances are described and the differential diagnosis discussed. Computer tomography clearly defines the proliferative-inflammatory process and together with conventional radiology, angiography and lymphangiography it permits a presumptive diagnosis of retroperitoneal fibrosis. The non-invasive nature of computer tomography makes it the method of choice for follow-up of this disease.

Aged↗

[Drainage following urological surgery].

Prolonged leakage of urine and infection are the most troublesome complications following surgical exposure of the lumen of the urinary tract. The available methods of wound and urinary drainage are discussed. Careful attention should be paid to the material from which the drain is manufactured, because of long periods of drainage in a closed system.

Drainage↗

[Transsexualism].

Explore the source record for details and available documents.

Diagnosis, Differential↗

Consequences to the upper urinary tract after ureteric torsion.

The effects of ureteric torsion on the upper urinary tract were studied in 8 pigs. With 5 pigs the distal ureter was mobilised, torted 1 to 5 times and reimplanted into the bladder. With three pigs the proximal ureter was torted 1 to 3 times and re-anastomosed to the renal pelvis. It was shown that a torsion of 1 or 2 times in the distal ureter does not result in ureteral obstruction. However, as little as 360 degrees torsion in the proximal ureter may lead to dysfunction secondary to mechanical obstruction. Histological examination of the ureter showed ischaemic changes only after multiple torsions.

Animals↗

[Catherer embolization of malignant urological tumors].

Transcatheter therapeutic arterial embolization with Spongostan was performed in 10 patients with inoperable malignant tumors of the urinary tract. It resulted in prompt and to some extent permanent relief and/or reduction of local tumor symptoms. Despite frequent transient side effects following occlusion, no permanent or serious complications have been directly attributable to the embolization.

Embolization, Therapeutic↗

Ileal substitute of ureter with reflux-plasty by terminal intussusception of bowel: animal experiments and clinical experience.

The conflicting results reported after substitution of the ureter by isolated bowel segments suggest that the procedure is still hazardous. This induced us to check experimentally the performance of the ileal ureter with antireflux-plasty before using it clinically. The antireflux mechanism is constructed by intussuscepting the terminal 8 cm. of an isolated ileal segment into each other thus forming a nipple. After vesicoileostomy the nipple protrudes into the urinary bladder. In the pig vesicoileorenal reflux was prevented, and anterograde urinary flow from the kidney through the ileal ureter into the bladder was unobstructed. Finally, the case of a patient is recorded who was submitted to the same procedure successfully.

Animals↗