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Biomedical subjects

E Yourassowsky

Publications and source records attributed to E Yourassowsky.

At least 163 records · Page 9Linked to original sources
PubMed1974

Automated count and size evaluation of colonies of bacteria grown in a zonal concentration gradient of antimicrobial agent.

The quantitative study (counting and size and surface evaluation of bacterial colonies) of the activity of an antimicrobial agent against a microbial population growing in solid medium can be performed by an electronic image analyzer. The Zeiss Micro-Videomat allowed the detection of even slight antimicrobial effects, which would be difficult to detect by colony counting alone and would escape the manual procedures of observation. The potential of the new method of investigation was illustrated by the examination of Staphylococcus aureus inhibition zones produced by disks of penicillin G and sulfadiazine.

Electronics↗
PubMed1974

Sensitivity of Streptococcus pyogenes to sulphamethoxazole, trimethoprim, and cotrimoxazole.

When tested on Wellcotest (sensitivity test agar, Wellcome) supplemented with lysed horse blood, 59 clinical isolates of beta-haemolytic streptococci, belonging to several serological groups, are all sensitive to sulphamethoxazole, to trimethoprim, and to cotrimoxazole. The results obtained on diagnostic sensitivity test agar (Oxoid) containing lysed horse blood are comparable. When Mueller Hinton agar (Difco) is used, some of these strains are called resistant: this is especially true in the case of sulphamethoxazole.Furthermore, on Mueller Hinton agar, even supplemented with lysed blood, discrepancies between diameters of inhibition zone and MIC values exist for the three drugs tested, strains with a low MIC being considered resistant by the disc method. Such disagreements are not observed with non-streptococcal control strains.

Animals↗