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Biomedical subjects

E Williams

Publications and source records attributed to E Williams.

At least 217 records · Page 12Linked to original sources
PubMed1982

Inhibition of [3H]diazepam and [3H]3-carboethoxy-beta-carboline binding by irazepine: evidence for multiple "domains" of the benzodiazepine receptor.

The binding of [3H]diazepam and [3H]3-carboethoxy-beta-carboline was examined in rat brain synaptosomal membranes treated with irazepine, an alkylating benzodiazepine. Under incubation conditions that resulted in a 25-33% reduction in the Bmax of [3H]diazepam binding, only modest (less than 8.5%) reductions in the Bmax of [3H]3-carboethoxy-beta-carboline were observed. The differential effects of irazepine on the binding of these two compounds may be explained by the presence of multiple areas or "domains" on the benzodiazepine receptor.

Animals↗
PubMed1982

Efficacy of ivermectin against third-stage Dirofilaria immitis larvae in ferrets and dogs.

Ivermectin prevented maturation of Dirofilaria immitis when given per os to ferrets at a dosage of 0 X 1 mg ivermectin per kg bodyweight two days after inoculation with third stage heartworm larvae. Similar results were found in dogs treated one day after infection at a dosage of 0 X 05 mg ivermectin per kg. No heartworm were found in the hearts and lungs of five treated dogs compared to an average of 11 worms per dog in five control animals.

Animals↗