[Bromosulfaleine test].
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Biomedical subjects
Publications and source records attributed to E Wildhirt.
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Six cases of persisting hepatitis with a duration of 3 to 9 years are reported. During this time 2--3 acute inflammatory episodes occurred with transaminase levels raised to more than 500 U/l. Icterus did not occur during these attacks. The remaining laboratory parameters which are usually normal in persisting hepatitis (gamma-GT, bromsulfalein) were pathological during the acute attack and later became normal. As the disease progressed after overcoming the attack, the transaminases were only slightly raised in all cases. Laparoscopy and histological examinations of between three and nine punctates gave an unchanged picture of chronic persisting hepatitis. During the acute attack the inflammatory activities in the liver punctates increased, there were also increased single cell necroses. It is suggested that this peculiar type of chronic persisting hepatitis shall be called "acute recurrent persistent hepatitis.".
The results of electron microscopic examination of renal biopsies from 3 patients with rheumatoid arthritis treated with penicillamine are presented. All 3 patients developed a nephrotic syndrome upon discontinuation of penicillamine therapy. When viewed with the electron microscope, segmental forms of perimembranous glomerulonephritis (Stages I-II of Ehrenreich and Churg) and glomerular renal amyloidosis Grade I-III were observed. In all three cases the nephrotic syndrome was considered to be due to the simultaneous occurrence of the two disease processes. In 2 cases perimembranous glomerulonephritis with immuno-complex-deposits was assumed to be the dominant factor in the causation of the disease, in the other case amyloidosis was the principle abnormality.
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A case report is given of a patient, who had been operated upon because of gall stones before; the gall bladder had not been removed. At a later date peritoneoscopy was planned and gas insufflated into the abdominal cavity in the usual manner; the patient did not complain about anything particular during peritoneoscopy. However adhesions apparently having formed after the earlier operation between the spleen and the abdominal wall did rupture during this procedure leading to a continously oozing hemorrhage from the spleen. At surgery 3 1 of blood were found in the abdominal cavity and splenectomy became unavoidable. This case report is given in order to draw attention to this sort of complication of peritoneoscopy.
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