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Biomedical subjects

E Wespes

Publications and source records attributed to E Wespes.

At least 91 records · Page 5Linked to original sources
PubMed1986

Impotence: evaluation with cavernosography.

Many patients with organic impotence do not have abnormalities of the penile arterial system. To determine the function of the venous system in erection, cavernosography was performed in 187 impotent men during artificial induction of erection with monitoring of intracavernous pressure and inflow. To evaluate the mechanism of active erection, 69 patients also received intracavernous injections of papaverine. Venous leakage was found in 88 patients. In these patients, a higher than normal rate of flow of diluted, heparinized contrast medium was required to initiate and maintain erection. Opacification of the prostatic plexus also occurred during erection in these patients. In all patients who received papaverine, the flow rates required to initiate and maintain erection decreased. The authors conclude that cavernosography and cavernometry are essential in the work-up of impotence and that papaverine may be helpful in elucidating the active mechanism of erection.

Adolescent↗
PubMed1986

[Venous exploration of impotence of vascular origin].

Vascular origin accounts for more than 25% of cases of disturbances of erection. Venous pathology may explain the majority of erectile dysfunctions in patients with normal arterial anatomy. We have performed cavernography in 115 patients with monitoring of intracavernous pressure. Nocturnal plethysmography was recorded in all cases to prove the organic etiology of the erectile dysfunction. Cavernography was realized after puncture of both corpora cavernosa by two microcatheters (19-21 G). The intracavernous pressure was recorded through 1 of them and the contrast medium infused through the other. The contrast medium is infused at a rate of 80-120 ml/min. until the penis appears erect. The simultaneous recording of the intracavernous pressure then showed a rapid increase of the pressure curve followed by a stabilization at greater than or equal to 90 mHg. The flow to maintain the erection reach 1/3 of the flow needed to induce the erection. The venous leak is characterized by the absence of erection, no increase in intracavernous pressure and a rapid opacification of the vein. Artificial erection induced in impotent men allows to classify patients with vascular organic impotence into three categories: those with pure arterial insufficiency, those with pure venous leak, and patients with both.

Adolescent↗
PubMed1985

Venous leakage: surgical treatment of a curable cause of impotence.

While the arterial aspects of erectile impotence recently have received considerable attention, the venous component of normal and impaired erection has been ignored. In this study venous leakage was demonstrated by inducing passive erections using a controlled perfusion of the corpora cavernosa with continuous pressure monitoring. In 20 patients with impaired erectile activity under a standardized flow (80 to 120 ml. per minute) no rigid erections were obtained and the perfused liquid was demonstrated to escape through the deep dorsal vein of the penis. After ligation of this vein the erections improved sufficiently to allow satisfactory intercourse in 16 of the 20 patients. The 4 failures had serious arterial lesions. In patients with organic impotence the venous pathological condition should be assessed routinely, since it represents an easily correctable anomaly if arterial inflow is not severely impaired.

Contrast Media↗
PubMed1985

Intra-arterial chemotherapy of infiltrative bladder carcinoma.

Twenty patients with untreated invasive high stage or high grade transitional cell carcinoma of the bladder have been treated by bilateral intra-arterial hypogastric injection of adriamycin. A total of 160 mg of adriamycin were injected during the procedure which was repeated once 3-4 weeks later. Eleven patients received two full courses of chemotherapy. In 4 patients, complete response with disappearance of all tumoral lesions was observed and in 1 patient, partial tumor regression was apparent. One patient died from pulmonary disease. Five patients received only a partial treatment because of technical difficulties, and selective catheterization was impossible in 4 because of severe arteriosclerotic lesions. No response was seen in those cases. Although this new therapeutic modality remains to be fully evaluated, preliminary results appear most encouraging since intra-arterial chemotherapy can be used safely and is effective in patients with invasive bladder carcinoma.

Aged↗
PubMed1984

Investigation of the venous system in impotence of vascular origin.

Vascular pathology is responsible for about 25% of cases of male impotence. Pudendal arteriography has been the object of numerous publications. Venous conditions explain the majority of erectile dysfunctions in patients with normal arterial anatomy. We have performed cavernography in 30 patients, with monitoring of intracavernous pressure and flow measurement. Cavernograms allowed study of the corpora cavernosa and the venous drainage. Cavernography not only helps in understanding the mechanism of erection but also is essential to the successful treatment of pathologic venous drainage.

Adult↗
PubMed1984

Parameters of erection.

Passive erection was obtained in 10 patients with normal erections without the use of any artificial mechanism of retention at the base of the penis. The necessary flow to provoke the erection ranged between 80 and 120 ml/min. Intracavernous pressure and penile circumference were also monitored until the appearance of a complete erection. This study showed that the maximum tumescent diameter of the penis was obtained before significant rigidity and thus explains the possible misinterpretation of nocturnal penile tumescence as a screening method for impotence.

Adolescent↗
PubMed1984

Cavernometry-cavernography: its role in organic impotence.

The intracavernous pressure necessary to produce a passive erection was recorded in 35 patients suffering from impotence. Among these patients, 5 presented psychogenic impotence. The intracavernous pressure was also recorded at rest during inflow and in the state of erection. The 5 psychogenically impotent patients had passive erections with a flow of 80-120 ml/min. 18 patients suffering from organic impotence developed passive erections at a flow of 80-120 ml/min, while the remaining 12 men needed a flow between 160 and 300 ml/min with visualization of a venous leak. The intracavernous pressure varied between 90 and 110 mm Hg in the state of erection. Artificial erection, induced in impotent men, allows to classify patients with vascular organic impotence into three categories: those with pure arterial insufficiency; those with pure venous leak, and patients with both.

Adult↗
PubMed1984

[Radiologic and hemodynamic studies of sexual impotence of vascular origin].

Vascular pathology is responsible for about 25% of male impotence, the arterial investigation is now classical. In our experience a great number of patients showed a normal arterial condition, requiring further venous exploration. Cavernographies and pressure flow dynamics were used to evaluate 45 patients. The cavernograms allowed visualization of structural abnormalities within the cavernous tissues and their venous drainage. The heparinized and diluted contrast medium is infused at 80 to 120 ml/minute until the appearance of an erection, in normal condition the intracavernous pressure rise at greater than or equal to 80 mmHg as long as the erection last. The venous leak is characterized by the absence of erection, no increase of the intra-cavernous pressure and a rapid opacification of venous plexus under a normal perfusion flow.

Adult↗
PubMed1984

[Endoscopic teflon injection in the treatment of female stress urinary incontinence].

Fifty six women with urinary stress incontinence were treated with transurethral teflon injections. Forty eight (86 per cent) were completely cured, or showed considerable improvement. No abscesses or other complications were noted, and hospitalization was reduced to two or three days. The procedure is easy to perform and does not preclude subsequent surgery, if required. It is particularly suitable for obese or debilitated patients, or patients who have previously undergone surgery without success.

Adult↗