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Biomedical subjects

E Thomas

Publications and source records attributed to E Thomas.

At least 433 records · Page 24Linked to original sources
PubMed1980

Faecal carriage of group B streptococci.

Consecutive stool samples from 116 female and 98 male patients (both adults and children), and rectal and vaginal swabs from 28 and 53 cases respectively, were quantitatively cultured for group B streptococci using Islam's medium. Group B streptococcus was recovered from 5% and 2% of faeces in female and male patients respectively, and the colony counts ranged from 10(2) to 10(3)/g. In women, the faecal carriage rate was 6%, which was significantly lower than the rectal carriage rate (p 0.02), suggesting that the higher recovery rate (27%) from rectal specimens may be due to contamination of swabs by perianal skin flora. Type II group B streptococcus was the only faecal isolate in adults (numbers involved are small for statistical significance), and we suspect that this type strain may be the only resident gut flora in adults, and the gastrointestinal tract is unlikely to serve as the main reservoir of all group B streptococci.

Adolescent↗
PubMed1980

Pathological and histomorphometric study of the effects of alcohol on the human duodenum.

Duodenal biopsies from 47 alcoholic patients and 21 nonalcoholics were examined histologically and the number of chronic inflammatory (mononuclear) cells in the lamina propria and of villus goblet cells was calculated using a cell-counting technique. The number of mononuclear cells was the same in both groups. Goblet cell hyperplasia, gastric metaplasia and changes in the villi and epithelium were found almost exclusively in the alcoholics. Mononuclear cell counts were higher in patients from both groups showing concomitant chronic gastritis. Goblet cells were more numerous in older patients; mononuclear cells in nonalcoholics showed a slight increase with age. Correlation between endoscopy and histology gave equivocal results.

Adolescent↗
PubMed1980

[Aspects of lung function evaluation before and after lung resections (author's transl)].

The preoperative cardiopulmonary function study should permit the chest surgeon to evaluate the risk of a planned resection. There are different opinions in the literature regarding the necessity and the number of lung function test. To evaluate the possible success of a lung operation one must take into account the loss of functional capacity due to the operation. The available tests of cardiopulmonary function are of different value for the evaluation of resectability. Traditional functional limits have to be examined carefully. There are test schemes and formulas to reduce the likelihood of postoperative cardiopulmonary failure through a most accurate preoperative lung function study. Our results of pre- and postoperative lung function tests confirme the well known experience that not limit values and formulas nor the clinical impression alone can give a true picture of resectability. Only by critically summarizing clinical findings, lung function tests and personality of the patient as well as his cooperability it is possible to have a low postoperative lethality while still giving the poor risk patients a reasonable chance.

Heart Arrest↗
PubMed1979

Histologic and morphometric study of chronic gastritis in alcoholic patients.

The effect of chronic alcohol ingestion on the gastric mucosa was determined in 96 patients in whom gastroscopy was performed because of upper gastrointestinal symptoms. Seventy-two patients were classified as alcoholics and 24 patients as nonalcoholics. In all cases biopsy specimens were taken from the fundus and antrum. The diagnoses of chronic superficial and atrophic gastritis were based on conventional histologic criteria and a morphometric technique utilizing quantitation of the chronic inflammatory cells in the lamina propria. Alcoholic patients were found to have a higher incidence of chronic gastritis of the antrum than nonalcoholics (p less than 0.001). Fundic involvement was also more common, probably accounting for the decreased gastric acid output described in chronic alcoholic patients. Finally, gastritis was more severe in the alcoholics; below 45 years of age chronic atrophic gastritis was seen only in alcoholics. We conclude that chronic gastritis develops more frequently in alcoholic patients and evolves into chronic atrophic gastritis at an earlier age than in nonalcoholic subjects.

Acute Disease↗
PubMed1979

[Fiber type disproportion, a subtype of so-called nonprogressive myopathies (author's transl)].

The clinical course, serological, and electromyographic findings, and also histological, histochemical, and electron microscopic abnormalities of two patients with congenital fiber type disproportion, a subtype of the so-called congenital nonprogressive myopathies, are described in this study. Other important subgroups are discussed regarding both variation and overlapping. As these diseases neither belong to the "classical" myopathies nor to the neuropathies, other possible factors such as a distrubed trophic function of the nerve or abnormalities of the reflex arc are under consideration.

Biopsy↗
PubMed1979

Hemorrhage due to retrograde prolapse of stomach. An endoscopic diagnosis.

A case of recurrent hemorrhage due to localized gastric mucosal congestion from retrograde prolapse during severe retching is described. Historically, this condition may mimic the "Mallory-Weiss syndrome" and endoscopically, this lesion may be mistaken for "gastritis". This rarely recognized condition may be an explanation for some cases of cryptic hematemesis.

Alcoholism↗
PubMed1978

The fine structural localization of acetylcholinesterase in the muscle spindle of the rat.

Muscle spindles from lumbricalis muscles of the rat were incubated for acetylcholinesterase with a modified thiocholine-method of Lewis and Shute and examined by light ane electron microscopy. All types of motor nerve ending showed heavy deposits of reaction product in the synaptic cleft. The underlying sarcoplasmic reticulum, transverse tubular system, and, when present, the envelope of sole plate nuclei were also stained. In the sensory region, the reaction was negative in the interface between the plasma membranes of the primary sensory terminal and muscle. One of two secondary sensory endings identified showed distinct reaction product in the cleft; the other secondary sensory ending showed no such reaction. Precipitates were present on the sarcolemma of the intrafusal muscle fibers in the polar and adjacent myotube regions, but not at the spindle equator. Extrafusal and intrafusal myelinated gamma-nerve fibers and preterminal motor axons showed staining of the axolemma. Fibers with thick myelin sheaths and preterminal sensory axons were free of acetylcholinesterase activity, as were the unmyelinated nerve fibers.

Acetylcholinesterase↗