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Biomedical subjects

E Riedel

Publications and source records attributed to E Riedel.

At least 73 records · Page 4Linked to original sources
PubMed1985

[Intrapericardial administration of drugs in the animal experiment].

Intrapericardially supplied agents for instance cardioactive drugs were transferred via lymph vessels in the myocardium likely. In case of dye application the myocardium and also the cardiac valves were coloured additionally. The effect on the heart should be more intensive and faster than after systemic application.

Animals↗
PubMed1985

[Experimental studies on the problem of improving the myocardial blood circulation in an intraoperatively resuscitated heart].

A pumping system for supporting an intraoperatively failured heart is presented. This system consists of a bell-shaped receptacle for the heart and a pump with a working volume of 49 ml and a working pressure of 220 Torr. The pumping power is transmitted to the heart by means of an external pneumatic pressure line. The efficacy of the pump in the high pressure system amounted to 20-30 per cent. An effective coronary perfusion in case of a cardiac failure is guaranteed by a venous underpressure pump of this pumping system. A favourable influence was also observed in case of the low pressure system.

Animals↗
PubMed1985

[Hemodynamics and morphologic changes following stroma-free hemoglobin solutions in animal experiments].

Hemodynamics and pathomorphological signs after infusion of a stroma-free hemoglobin solution with defined stroma rest contend were registered in 24 minipigs. The small intravascular persistence and potential toxicity were the disadvantages of the solution. We noted a falling down of the central venous pressure and an ascent of the middle arterial pressure so the total peripheral resistance.

Acid-Base Equilibrium↗
PubMed1984

[Calculation of normal values in lung compliance].

Within a study of standard values, investigations of the static and dynamic lung compliance were performed in 162 test persons in a good state of health of heart and lungs. Age, size, constitution, and intrathoracical gas volume are necessary parameters for calculation of an individual standard value of the dynamic compliance, whereas age and intrathoracical gas volume only are needed for calculation of a standard value of the static compliance. The new standard values are compared with the values known from the literature.

Adolescent↗
PubMed1983

[Obstruction parameters and pulmonary artery pressure in asthmatics after administration of aminophylline].

In 30 asthmatics after the application of aminophylline the measurement of the pressure of the pulmonary arteries as well as of the parameters of the respiratory function FEV1.0 and Rt was performed. It is proved a significant decrease of pressure in the lesser circulatory system. The reduction of the bronchial obstruction cannot be proved by means of the respiratory impulse test (FEV1.0), but by the determination of the resistance to respiration (Rt).

Adult↗
PubMed1983

[Experimental studies on the effect of the administration of oxygen into the pericardial cavity in acute myocardial ischemia].

Artificial myocardial ischaemia caused by ligation of the left anterior descending coronary artery was treated in minipigs by the application of oxygen into the pericardial cavity. The results show that in this way acute myocardial ischaemia may be reduced. The application of oxygen into the pericardial cavity brought about, within 15 min, an improvement in the haemodynamic parameters. Several electrolytes, which were estimated from the blood of the sinus venosus, returned to normal.

Animals↗
PubMed1983

[Perfusion of the ischemic myocardium in the acute phase of a myocardial ischemia using a stroma-free hemoglobin solution].

Concerning the effect of the perfusion of ischemic areas of the myocardium by a stroma-free hemoglobin solution was reported after the starvation of the interventricular branch of the left coronary artery (RIVA) in minipigs. The effect of the perfusion is dependent on the kind of the vascular course. The perfusion of the distal part of the starvated coronary artery shows the better reaction in face of the artemalization of the concomitant cardiac vein with regard to the resaturation of the myocardium with oxygen and several hemodynamic control parameters. Histologic examinations of the ischemic myocardium after the arterialization of the cardiac veins showed however that the symplasm preserved its vitality and showed only reversible changes. The applied stroma-free hemoglobin solution needs a further development. However, the use is possible on principle according to the bibliography. Whether a new clinical therapy could be developed by a transitory arterialization of the cardiac veins in acute myocardial ischemia, should be discussed.

Animals↗
PubMed1983

[Dynamics of the heart rate in active orthostasis of patients with hemodynamically effective mitral valve stenosis].

Heart rate dynamics in response to active orthostasis of 10 min duration were examined in 48 patients with mitral stenosis and compared with the mean and diastolic pulmonary artery pressure. Classification of the characteristics of the heart rate was done according Drischel and co-workers (1963) using amplitude and time values. In contrast to healthy subjects, in patients with mitral stenosis the best regulatory behavior was observed in type B with lower pulmonary artery pressure, the least favorable regulatory dynamics being predominant in type A with higher pulmonary artery pressure. From a functional diagnostic point of view, regulatory efficiency can be graded on the following descending scale: (1) the best regulatory behavior in type B; (2) a decrease in the amplitude values in type B; (3) transition of the dynamics to type A; and (4) prolongation of the time values in type A. The pathophysiological mechanisms are changes in the sensitivity of dilatation receptors in the intrathoracic low-pressure system and of the carotid baroreceptors.

Blood Pressure↗
PubMed1983

[Remarks on the "pure alexia" syndrome--a case report].

The article describes a case with the "pure alexia" syndrome caused by an infarct of the arteria cerebri posterior sinistra during a diffuse cerebral vascular disease. The authors consider the alexia to be a consequence of difficulties in transcoding graphic into graphemic structures.

Aged↗
PubMed1982

Quantitative thin-layer chromatographic determination of dihydroergot alkaloids.

Direct, quantitative, thin-layer chromatographic methods for the determination of dihydroergot alkaloids are described, in particular the determination of dihydroergotamine with dihydroergokryptine as internal standard. The internal standard was added to plasma, which was extracted twice in dichloromethane; the organic phase was removed under nitrogen, the residue resolved in ethanol and applied on a silica gel G-60 plate. Dihydroergotamine and the internal standard can be measured directly by fluorescence, with excitation at 264 nm and with use of a Zeiss remission filter FL 39. The percentage recovery from this method is 49.17 +/- 6.71% (plasma). These methods enable the determination of 10 pmol dihydroergotamine per ml of plasma (ca. 6.8 ng/ml) with a coefficient of variation of 10.3%. They have proved useful in biochemical and pharmaceutical applications.

Chromatography, Thin Layer↗
PubMed1982

[Resorption of pharmacologic substances and oxygen by the myocardium following application into the pericardial cavity].

The epicardium as a biological substrate is able to absorb. We were able to observe the absorption of pharmacological substances and the physically dissolved oxygen as well as the gaseous oxygen after the application into the pericardial cavity by experiments in narcotised mini-pigs. The oxygen absorption by the epicardium led to the retrogression of an artificially caused myocardial ischemia.

Absorption↗
PubMed1981

[Alveolitis--its effect on lung circulation].

29 patients with exogenous allergic alveolitis and 57 patients with chronic fibrosing alveolitis were examined. Lung function and blood gas analytical parameters and the pressure of the pulmonary artery in rest and during load were investigated in all persons. The measured results of the two groups of patients were compared. In all patients a restrictive disturbance of ventilation and a hypoxemia were established. 34 patients showed an increased pressure of the pulmonary artery in rest, in 22 patients an elevated pressure in the pulmonary circulation on loading conditions was measured. By reason of different loading pressures all 85 patients were divided into 3 groups, where their function patterns were discussed. The special importance of evidence of loading investigations in pressure measurements in the pulmonary circulation is discussed.

Adolescent↗