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Biomedical subjects

E Redondo

Publications and source records attributed to E Redondo.

At least 73 records · Page 4Linked to original sources
PubMed1989

Paratesticular metastases from congenital retroperitoneal tumor.

A retroperitoneal tumor was removed from a fifteen-day-old infant. Light microscopy revealed a teratoma consisting mainly of immature nervous tissue. Three months later the patient had recurrence and numerous peritoneal metastases showing a histologic pattern similar to that of the primary tumor. Twelve months later there was enlargement of the left testis due to metastases from teratoma infiltrating the tunica vaginalis of the left testis, the epididymis, and the spermatic cord. These metastases consisted of mature neurons and glial cells. The early dissemination of the tumor suggests an intracavitary spread pattern. The tumor maturation in paratesticular structures suggests that mesothelial cells are involved in the differentiation of tumoral germ cells.

Combined Modality Therapy↗
PubMed1989

A histopathological and morphometrical study of femur head cartilage in Wistar rats treated with prednisolone.

An analysis was made of histopathological developments in femur head cartilage in a group of Wistar rats receiving a daily intra-muscular injection of 2.5 mg prednisolone. This group was divided into four experimental batches, each consisting of 6 rats. Batches were sacrificed at 15, 30, 60 and 90 days after the start of the experiment. Degeneration of the femur head cartilage was observed from the start of the experiment (15 days), and gave rise to chondrocyte necrosis by 90 days. Structural modifications are shown morphologically and morphometrically.

Animals↗
PubMed1989

Glomerular filtration barrier in experimental endotoxin shock: a histopathological and physiopathological study.

In the present work a morphopathological study is carried out of the glomerular filtration barrier in 20 Large-White pigs weighing 20 kg, subjected to experimental intravenous inoculations of endotoxin from Salmonella enteritidis. The study is completed with the determination of protein plasmatic levels, through urine test with the determination of pH, density, proteins, glucose, ketone body levels and urinary sediment. The histopathological and physiopathological results reveal alterations at the level of the filtration barrier with quantitative differences between the different experimental groups.

Animals↗
PubMed1989

[Multicentric reticulohistiocytosis: histochemical, histoenzymatic and immunocytochemical study].

Report of a case of multicentric reticulohistiocytosis with clinical, histopathologic, histochemical and immunohistochemical study. Neutral mucins and lipids were demonstrated in the cytoplasm of dermal histiocytes. The monocyte-histiocytic nature of the cells was shown by means of acid phosphatase, ATP-ase, muramidase and alpha-1-antitrypsin. Due to the immunohistochemical results, the relationship with Langerhans cells was rejected. No secretory activity of immunoglobulins was shown and the proliferation qualified as benign. The cells among the histiocytic population were typified as mature T lymphocytes.

Adult↗
PubMed1988

Juvenile granulosa cell tumor of the testis.

Juvenile granulosa cell tumor occurred in a newborn. The tumor presented with testicular torsion, and no malformations were observed. The karyotype was normal. The occurrence of initial tumoral lesions in the seminiferous tubules located in the vicinity of the tumor suggests that the tumor originated from immature Sertoli's cells. To our knowledge, this is the tenth case reported in a newborn and the second associated with testicular torsion.

Granulosa Cell Tumor↗
PubMed1987

Tubular embryonal remnants in the human spermatic cord.

The spermatic cords (SCs) obtained from: (a) autopsies of 67 adults and 50 children; (b) 3 fetuses; (c) 12 surgical specimens from 9 adults and 3 children with testicular tumors, and (d) 26 surgical specimens (14 adults and 12 children) with diagnosis of SC cysts, were studied by light microscopy. The histological study revealed the occurrence of tubular embryonal remnants (TERs) in 19 autopsied adults, 14 autopsied children, 3 fetuses, 2 surgical specimens (1 adult and 1 child) owing to testicular tumors, and 6 surgical specimens with diagnosis of SC cysts. The TERs were found in the low, middle or high thirds of the SC and consisted of a cuboidal or columnar, often ciliated epithelium surrounded by connective tissue. In the 3 fetuses and in 3 autopsied children renal glomeruli were found in close relation with the TERs. In 2 cases of SCs showing cysts and TERs both structures contained spermatozoa. The histological pattern of the TERs suggest that they are wolffian derivatives which might give rise to SC cysts.

Adult↗
PubMed1987

Glomerular histopathology of the contralateral kidney in experimental unilateral hydronephrosis.

The aim of this study was to examine the structural, ultrastructural and morphometric alterations which take place in the contralateral kidneys of rats with experimental unilateral hydronephrosis. 20 Wistar rats weighing 250 g., affected by a process of unilateral hydronephrosis following the ligature of the ureter, were used; these rats were then killed 40, 50, 60, or 70 days after the ligature. Among the perceived alterations, were immunoglobulin G deposits shown by positive immunoperoxidase reaction and increase in the size of the glomerular and corpuscle from around the fortieth day, and structural alterations that included the pedicles, electrondense deposits in the podocytes and pseudogranular structures in the basal membrane of the capillary.

Animals↗
PubMed1986

[Anderson's disease. Apropos of a new case].

A new case of Anderson's disease in a 3-month-old black female infant is presented. This diagnosis should be considered in infants with chronic diarrhoea, fatty stools, failure to gain weight which may be present from birth, low serum cholesterol concentration (less than 70 mg/ml), low plasma triglyceride levels, and hypobetalipoproteinaemia. However, suspicion of diagnosis clinically can be certainly verified by intestinal biopsy showing characteristic epithelial cell pattern. Steatorrhoea may be effectively treated by substituting medium for long-chain triglycerides in the diet. This disorder needs to be distinguished from familial hypobetalipoproteinaemia as well as abetalipoproteinaemia, and it prognosis is good, because of absence of acanthocytosis, neurological involvement and ocular lesions.

Abetalipoproteinemia↗
PubMed1985

Cystic intra-abdominal testicular torsion in an infant.

We report on a 3-month-old infant with cystic intra-abdominal testicular torsion. He presented with abdominal distension and pain. Physical examination showed a movable, well delineated mass in the right iliac and lumbar fossae. Exploration revealed that the mass was connected to the abdominal aorta by a thin vascular cord that was twisted before reaching the mass. The histological study showed that the mass corresponded to a testis with cystic formations. The testicular parenchyma was necrotized, although isolated seminiferous tubules were found. The cystic cavities were filled by hematic and necrotic material, and exhibited no epithelial lining. A fibrous layer in continuity with interstitial hemorrhage surrounded the cysts. The twisted vascular cord corresponded to a spermatic cord with dilated pampiniform plexus veins. The differential diagnosis and the etiopathogenesis of the lesion are discussed.

Abdomen↗
PubMedDate not supplied

[Warthin's tumor: clinical aspects and a cytological study using fine-needle puncture-aspiration in 16 cases].

The clinical and fine-needle cytologic findings of 16 Warthin's tumors (papillary cystadenoma lymphomatosum) are presented. They were studied during a period of 38 months, between February 1987 and April 1990. A preoperative diagnosis of "Warthin's tumor" was made in 13 cases (80%); 3 cases were diagnosed as non neoplastic benign lesions (2 retention cysts and 1 chronic sialoadenitis). 10 cases were surgically excised and preoperative diagnosis was histologically confirmed. We compare the cytologic findings of our cases with the literature ones.

Adenolymphoma↗
PubMedDate not supplied

[Primary neuroendocrine carcinoma of the pavilion of the ear].

We present a case of primary neuroendocrine carcinoma (Merkel cell carcinoma) of the external ear and its treatment. This paper also deals with histogenesis, pathology, clinical findings, diagnosis and treatment of this tumor.

Antineoplastic Combined Chemotherapy Protocols↗