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Biomedical subjects

E Palacios

Publications and source records attributed to E Palacios.

At least 91 records · Page 5Linked to original sources

[Effect of thioacetamide on the incorporation of 32P into phospholipids of rat liver].

The effect of thioacetamide on rat liver phospholipids biosynthesis was investigated using 32P as precursor. The incorporation of 32P-ortophosphate in the polar lipid fraction and the specific radioactivities of individual phospholipids in the liver fraction and the specific radioactivities of individual phospholipids in the liver of control rats and rats treated with thioacetamide were determined 75 min after intraperitoneal administration of 32P-ortophosphate. Intraperitoneal injection of thioacetamide (daily dose of 100 mg/kg body weight) in male Wistar rats resulted in an increase of 32P incorporation in the over-all phospholipids, after 8 doses administration and a significant decrease during the chronic intoxication. Specific activity of phosphatidylcholine decreased and a parellel increase in specific radioactivity of lisophosphatidylcholine was found after three days of thioacetamide treatment. There was also observed a marked increase in specific radioactivity of sphingomyelin, which could be due to a stimulation of CDP-choline: ceramide cholinephosphotransferase reaction with subsequent diminution of the rate of phosphatidylcholine synthesis via the CDP-amine pathway (involving cytidine diphosphocholine).

Acetamides↗

Cerebellar degeneration with Hodgkin's disease: computed tomographic correlation and literature review.

A 62-year-old man with progressive cerebellar degeneration, corticospinal tract dysfunction, and mild dementia was found to have Hodgkin's disease. Serial computed tomographic studies revealed progressive cerebellar atrophy. The clinical features and neuroradiologic studies in nine previous cases are reviewed. A thorough search for lymphadenopathy should be made in patients with unexplained cerebellar degeneration.

Atrophy↗

Postischemic hypervascularity of infancy: a stage in the evolution of ischemic brain damage with characteristic CT scan.

One to 2 weeks after severe brain ischemia, four infants developed an unusual vascular lesion with a characteristic appearance on computed tomography that has not been reported previously. Restricted areas (most frequently the basal ganglia and thalamus) displayed increased attenuation, which enhanced further upon infusion of contrast medium. Autopsy of one infant revealed that the CT abnormality corresponded to an extremely dense neovascular network which had almost completely replaced the parenchyma in that region. We postulate that this pathological change is a stage in the organization of ischemic brain damage reflecting the infant's vascular plasticity. Thus, hypoxia induces marked capillary proliferation in regions of normally high metabolism and capillary density. The CT pattern may prove useful in predicting the location and extent of sequelae to perinatal asphyxia.

Asphyxia Neonatorum↗

Computed tomography of sphenoid wing meningiomas: tumor location related to distal edema.

A review of the computed tomography and clinical characteristics of a series of sphenoid wing meningiomas revealed a high incidence of edema involving the ipsilateral cerebral hemisphere. This edema frequently accounted for the clinical presentation indicating the non-localizing insidious nature of these tumors. The etiology of the edema appears to be related in parts to the location of tumor in the middle cranial fossa and its proximity to the major venous pathways of this area.

Aged↗

Angiographic demonstration of recanalization of the basilar artery.

This report details the clinical course and angiographic findings of a patient with intermittent vertebrobasilar insufficiency. Recanalization of the basilar artery was demonstrated during anticoagulant therapy. A review of the literature failed to disclose a previous report of this occurrence.

Basilar Artery↗

Unusual metastases from a medulloblastoma: case report.

Calvarial and extracranial metastases by hematogenous spread of primary intracranial neoplasms have been considered a rare occurrence. This report deals with the clinicopathological and radiological findings of a child with metastatic medulloblastoma. Correlation of serial postoperative computed tomography (CT) scans and the autopsy examination indicated hematogenous calvarial and intracranial spread of the primary lesion.

Brain Neoplasms↗

Computed axial tomography in otorhinolaryngology.

The value of computed tomography in ORL and its applications have been briefly discussed. Better soft tissue detail and its relationship to bony structures is obtained. At the present time this modality may be utilized as a screening test in some suspected cases or as an adjunct of conventional methods. With the technical refinements that are constantly being made, better diagnostic information will be obtained in CT scanning.

Brain Neoplasms↗

Diagnosis of sellar and parasellar lesions by computed tomography and other diagnostic modalities.

A review of 5,000 computed tomographic (CT) brain scans revealed 76 patients with proved pathology involving the sellar and parasellar areas. The overall diagnostic accuracy of CT scanning was 93.4%, whereas the accuracy of isotope scanning, angiography, and pneumoencephalography was 55.4, 81 and 100% respectively. The criteria used in making the diagnosis with CT scanning are listed. The results indicate that CT scanning is the initial diagnostic procedure of choice, but that other modalities, particularly angiography, are still required for more accurate evaluation in the majority of cases.

Cerebral Angiography↗

Radiology of cysticercosis of the central nervous system including computed tomography.

Cysticercosis is a parasitic disease in which man serves as the intermediate host of Taenia solium, the pork tapeworm. The larvae have a predilection for the central nervous system and can cause a variety of neurologic and psychiatric symptoms. Areas of involvement are classified as intraventricular, parenchymal, arachnoidal, and mixed. The diagnosis is made primarily by roentgenographic and spinal fluid examinations. The authors reviewed 232 cases of cysticercosis involving the central nervous system. It was found that computed tomography is a useful tool in assessing this illness.

Adolescent↗

Neuroepithelial (colloid) cysts. Pathogenesis and unusual features.

A brief history of the theories of pathogenesis of the origin of neuroepithelial cysts is presented. An origin more diffuse than the paraphysis seems most likely in our opinion, and we attempt to substantiate this theory with several of the cases from our series. One posterior third ventricular neuroepithelial cyst and one in the fourth ventricle are demonstrated roentgenographically. Also included in our series are a case showing suprasellar calcification on plain skull roentgenograms, not previously reported in neuroepithelial cysts, and a case with a cyst measuring 9 cm, the largest neuroepithelial cyst yet reported.

Adult↗

The significance of the dural supply from the carotid siphon.

The dural branches from the cavernous portion of the internal carotid consists of the meningophypopseal trunk, the inferior cavernous, and the capsular arteries. These vessels have extensive anastomoses in and around the sellar area. These arteries are not usually demonstrated angiographically; therefore, when they are enlarged, a pathological lesion should be suspected. There are numerous lesions other than meningiomas associated with hypertrophy of these dural branches and the corresponding vessels involved depends on the anatomic location of the associated lesion.

Adenoma, Chromophobe↗