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Biomedical subjects

E O Adekeye

Publications and source records attributed to E O Adekeye.

At least 37 records · Page 2Linked to original sources

Advanced central myxoma of the jaws in Nigeria. Clinical features, treatment and pathogenesis.

18 advanced cases of myxoma of the jaws are described. These had a typical age, sex and site distribution and characteristic clinical and radiographic features. Surgical treatment was radical as benefits large, poorly defined tumours, but there was no evidence that these were aggressive lesions. It is argued that the designation of myxoma as an odontogenic tumour is uncertain though not excluded. Attention is drawn to evidence that many myxomas of the jaws may be examples of myxomatous degeneration in other neoplasms.

Adolescent↗

Neurofibromatosis of the head and neck: clinical presentation and treatment.

The clinical features of neurofibromatosis of the head and neck in 28 Nigerians are presented. The disease produced varying degrees of cosmetic and functional deformity. Total excision of the lesions, where feasible, with skin grafting, when indicated, gave satisfactory cosmetic and functional results. Incomplete excision was unsatisfactory for all eyelid and other more extensive lesions. Intraoperative bleeding was prominent and postoperative follow-up poor.

Adolescent↗

Surgical parotid disease in Nigeria: a review of 100 cases.

100 cases of surgical parotid disease are reviewed. Parotid cyst was the commonest non-neoplastic disease, followed by a parotid fistula. 73% of the cases were neoplastic conditions of which approximately 50% were malignant and the patients were much younger than those reported in other series.

Adolescent↗

Giant frontal sinus mucocoele. Report of two cases.

The giant frontal sinus mucocoele is best approached surgically using a bi-coronal flap to give an ample view of orbital and intra-cranial extensions. The size of the cystic cavity necessitates packing rather than obliteration with autografts. Reconstruction of the frontal bone may be carried out as a secondary procedure.

Female↗

Ankylosis of the mandible: analysis of 76 cases.

A survey of 76 cases of ankylosis of the mandible in Nigerians is presented. Etiology, clinical features, radiographic findings, anesthetic techniques, surgical treatment, complications, and results are discussed. The operative technique used in each case depended on the site, extent, and type of ankylosis. Five-year follow-up data are reported. Of the 47 patients who were followed, the postoperative interincisal opening was retained in 25 (53.2%), varying degrees of reduction of mouth opening were observed in 17 (36.2%), and ankylosis recurred in five (10.6%). Lack of jaw opening exercise was believed to be responsible for relapse.

Adolescent↗

Cancrum oris: principles of management and reconstructive surgery.

A survey of 140 cases of cancrum oris in Nigerian Africans is presented. The salient clinical features, the problems of management and the modern approaches to the reconstruction of facial deformities seen in this disease are described. Mainly affected were children under the age of 10 years and the commonest involvement was the full thickness of the cheek. A high incidence of ankylosis was noted and the methods of anaesthesia and surgical correction of ankylosis are examined. The number of patients presenting for reconstruction of facial defects due to cancrum oris appears to be increasing. Preventive measures that may reduce the incidence of the disease are suggested.

Adolescent↗

The pathogenesis and microbiology of idiopathic cervicofacial abscesses.

Sixty-three cases of idiopathic cervicofacial abscesses were surveyed. Several debilitating conditions, probably responsible for diminished resistance to infection, were found in association with the abscesses. The condition mainly affected children under two years of age, and the submandibular and submental regions were the most common sites of occurrence. The predominant infecting organism was Staphylococcus aureus. The abscess cavity was a statistically significant source of S. aureus, but the nose, ear, mouth, and skin did not appear to be significant sources of the pathogen. Antibiotics such as Dalacin C and gentamicin were found to be active against all the strains of S. aureus. Although incision and drainage was the most effective method of treatment for the abscesses, appropriate antibiotics may be prescribed for those cases where suppuration has not yet taken place.

Abscess↗

The pattern of fractures of the facial skeleton in Kaduna, Nigeria. A survey of 1,447 cases.

A survey of 1,447 Nigerian patients with fractures of the facial skeleton is presented. The frequency and etiology of the fractures are described. Patients mainly affected were in the third decade of life. The male:female ratio is strikingly high, and the site distributions of the fractures are recorded and compared with those of other series. The cause of delay in reporting for treatment is examined, and the subsequent sequalae are outlined. Life-endangering injuries occurred in association with facial fractures. The necessity for teamwork between surgical specialists is emphasized. All fractures were treated by simple methods of fixation.

Accidents, Traffic↗

Pediatric fractures of the facial skeleton: a survey of 85 cases from Kaduna, Nigeria.

A survey of 1,447 cases of fractures of the facial skeleton from Kaduna, Nigeria, showed that 85 cases (5.9%) occurred in children younger than 13 years. The lowest incidence recorded was in the group of patients younger than age 3 but there was a gradual increase up to the age of 13 years, with the highest incidence occurring in the 12- to 13-year-old age group. The male-to-female ratio was 2.1 to 1. The site distribution in descending order of frequency was body of the mandible, mandibular condylar process, angle of the mandible, malar and nasal complexes, maxilla, and ascending ramus of the mandible. Most of the fractures were immobilized by simple methods, and union was achieved within two to six weeks. Of the 12 fractures of the condylar process, ankylosis of the temporomandibular joint developed in six; in addition, two had mandibular undergrowth.

Adolescent↗

Fractures of the zygomatic complex in Nigerian patients.

A survey of 337 Nigerian patients with fractures of the zygomatic complex disclosed that almost 96% involved males, more than 80% were between 21 and 40 years old, and 82.2% were caused by traffic accidents. The incidence of fractures caused by traffic accidents, falls, and sports was not significantly higher on the left side of the face than on the right, but those resulting from fights occurred significantly more often on the left side of the face. The highest incidence of fractures occurred during the rainy season and the month of December. Delay in reporting for treatment contributed considerably to the problems of management and to complications. About 47% of the patients required no active treatment, whereas approximately 41% had simple elevation; the overall complication rate was 8.9%.

Accidents, Traffic↗

Ameloblastoma of the jaws: a survey of 109 Nigerian patients.

A survey of 109 cases of ameloblastoma of the jaws in black Africans from Nigeria is presented. The neoplasms were removed by radical resection or by en bloc excision with preservations of the inferior border of the mandible. In selected cases, reconstruction was done using autogenous bone grafts or a Bowerman-Conroy prosthesis. Where the mandibular symphysis was not resected, adequate functional and esthetic results were achieved without reconstruction. All the bone grafts were successful, but most of the Bowerman-Conroy prostheses were rejected because of either infection or mechanical failure. Eight-year follow-up data were recorded; 35 patients were lost to follow-up, and of the 74 who were followed up, 31 (41.9%) were free of the disease for five years or more. Although complete excision was achieved in all the cases, there were three recurrences subsequent to segmental resections.

Adolescent↗

Ameloblastic fibrosarcoma. Report of a case in a Nigerian.

Ameloblastic fibrosarcoma is very rare and has not previously been reported from Nigeria. The case described here had typical clinical features, but the microscopic findings were unusual and difficult to interpret. The pathogenetic relationship between ameloblastic fibroma and fibrosarcoma is discussed.

Adult↗

Cervicofacial abcesses of unknown origin. A survey of eighty-one cases.

A survey of eighty-one patients with cervicofacial abscesses of unknown origin is presented. The salient clinical features and the treatment of the abscesses are described. Mainly affected were children under 4 years of age, and the submandibular and submental regions were the most common sites of involvement. Staphylococcus aureus was the predominant pathogenic organism, and epidemic strains were implicated in some cases. A high incidence of resistance to penicillin was noted. The nasal vestibule is postulated to be reservoir of the organisms, and the possible relationship between infection, malnutrition, and a mild degree of anemia is examined.

Abscess↗