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Biomedical subjects

E Morales

Publications and source records attributed to E Morales.

152 records · Page 9Linked to original sources
PubMedDate not supplied

[Clinical development of the in-hospital phase of acute myocardial infarction in patients treated with intravenous streptokinase].

In order to determine the clinical in-hospital course of patients with acute myocardial infarction treated with intravenous Streptokinase (SK), 132 patients were studied divided as follows: Group I: 44 patients who arrived to the hospital within 6 hours from the onset of symptoms and received fibrinolytic therapy. Group II: 44 patients who arrived more than 6 hours delay and did not receive SK. Group III: 44 patients who arrived less than 6 hours delay but they did not receive SK. The overall hospital mortality was 2.2% in the SK recipients versus 4.4% in the group II (Odd ratio 0.95, p = NS) and 13.6% in group III (Odd ratio 0.79, p greater than 0.05). The incidence of hemorrhagic episodes was not increased in SK recipients. In-hospital period differences between groups were explained by protocol studies and postoperative complications in patients that needed further revascularization procedures.

Aged↗
PubMedDate not supplied

[Myocardial ischemia in aortic stenosis].

In hypertensive heart disease without coronary artery disease it has been proposed that the presence of ischemia of myocardial tissue is due to an inadequate increment of myocardial mass or to an increase in coronary artery resistance. In this study, 18 patients with aortic stenosis, without coronary artery disease were included. It was demonstrated that the existence of myocardial ischemic, induced by atrial pacing and manifested by ST segment depression, had direct association to increased myocardial mass, and it had no relation with left ventricular telediastolic pressure nor with transvalvular gradient. The results support the hypothesis that an inappropriate increment of the myocardial mass is the main cause of myocardial ischemia in these type of cardiopathies.

Adolescent↗
PubMedDate not supplied

[Contribution to a systemic interpretation of anorexia nervosa].

The different ways in which anorexia nervosa has been understood throughout history are briefly described. Reference is made to those investigations underlining the role of the family in its pathogenesis, mainly to the papers on this subject that the authors themselves have published in the decade of the 70s. Then, an attempt of a systemic interpretation of anorectic syndrome is made, starting from the assumption that this acquires specific interactional characteristics in and for the family system in which uit has emerged. The more specific goals of this paper would be: to accurately describe the interaction forms of the system and sub-systems of anorexia nervosa; to put in evidence the function of the fundamental symptom, starvation; and finally, to make an approach to an eventual therapeutic intervention on the "anorectic" system.

Adolescent↗
PubMedDate not supplied

[New records of human diphyllobothriasis in Chile (1981-1992), with a case of multiple Diphyllobothrium latum infection].

Fifteen new human cases of diphyllobothriasis in Chile are reported, one of them a multiple case of infection by Diphyllobothrium latum. Five scolices and 28 m of strobila were recovered after treatment with Niclosamide in a male adult patient with multiple infection. In other 5 cases, after treatment, only one worm was recovered in each person and all corresponded to D. latum species; worms measured between 2.9 to 11.0m. In 9 cases, only the eggs of parasites were reported in the coprological exam. Thirteen cases were determined in the lakes area from south of Chile where infection by plerocercoids in salmonids is very frequent and the persons consume smoked and raw ("cebiche") fishes.

Adolescent↗
PubMedDate not supplied

[Increase of renal dopamine production induced by nifedipine in hypertensive patients. Double blind vs placebo study].

Dopamine is synthetized and excreted by kidneys, this amine exerts its natriuretic and diuretic effects by inhibition of sodium reabsorption on kidney convoluted tubules. The objective of this study was to verify the changes of dopamine urinary excretion induced by nifedipine-LP treatment in hypertensive patients. Twenty four patients with essential hypertension (stages 1, 2) were included in this double-blind, placebo controlled study. Twelve patients received nifedipine (average daily dose, 21.5 mg/day) for 4 weeks, and 12 patients received placebo for the same time period. No significant changes were detected upon nifedipine treatment neither in plasma biochemical nor hematological parameters. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) was significantly reduced from pretreatment values 168.0 +/- 8.7 mmHg and 102.0 +/- 5.2 mmHg respectively, to end-treatment values 140.0 +/- 6.6 mmHg and 88.0 +/- 5.6 mmHg (p < 0.05). Placebo treatment did not modify SBP and DBP. Urinary dopamine excretion increased by 53% from 679.5 +/- 80.1 micrograms/24 h prior to treatment to 1040.0 +/- 110.1 micrograms/24 h after treatment (p < 0.009. 95% Confidence Interval of the Difference: -538.9 to -183.6). Urinary volume of nifedipine treated patients increased from 1613 +/- 85 mL/24 h to 1920 +/- 160 mL/24 h post-treatment (p < 0.05). No significant changes were observed in urinary noradrenaline and adrenaline excretion in nifedipine or placebo treated patients. Analysis of fluorescent light excitation and emission spectra (200 nm to 800 nm) of dopamine extracted from patient's urine submitted to nifedipine treatment did not reveal any interference when compared to chemically pure dopamine. If is concluded that nifedipine treatment of hypertensive patients increases kidney dopamine production which in turn can exert a natriuretic and diuretic effect besides its well known vasodilator properties.

Adult↗