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Biomedical subjects

E Mallet

Publications and source records attributed to E Mallet.

154 records · Page 9Linked to original sources
PubMedDate not supplied

[Hyperparathyroidism in deficiency rickets. Changes after vitamin therapy].

The study concerned 16 cases of deficiency rickets observed over 3 years. The level of serum parathyroid (IPTH) hormone was always increased in the late stages of rickets, but was normal in 3 cases of early rickets with hypocalcaemia and monophosphataemia. There was no statistical correlation between the level of IPTH and monophosphataemia. There was no statistical correlation between the level of IPTH and calcaemia. After vitamin D-therapy, the levels if IPTH returned to normal in 5 to 21 days in most cases. No obvious difference was noted in this evolution between children treated by vitamin D2 and 25 OH D. The excretion of urinary cyclic adenosine monophosphate decreases in parallel with blood IPTH.

Cyclic AMP↗
PubMedDate not supplied

[Value and role of esophageal scintigraphy in the diagnosis of gastroesophageal reflux in infants and children].

There were 50 children with a strong clinical suspicion of gastrooesophageal reflux and 10 controls patients evaluated with gastrooesophageal scintiscans. 500 microCi to 1 mCi of Tc sulfur colloïd mixed the patients routine milk or formula feeding was administered and serial images of the abdomen and thorax were obtained. A positive scintiscan was found in 35 patients (sensitivity 70 %) and none of the controls (specificity 100 %). A comparison of findings in 34 patients referred for both radiographic and radionuclide studies showed that barium studies were positive in 38 % and radionuclide in 64,7 %. We found this examination to be more sensitive that the standard barium radiography particularly in patients with respiratory symptoms. We conclude that the GE scintiscan is complementary to barium studies in the diagnosis of GE reflux. Pulmonary aspiration of gastric contents was detected in only a case of the 35 patients with documented GE reflux. A T 1/2 emptying gastric more long that 90 minutes (linear calculationation) or 115 minutes (exponential calcul) is an indirect GE reflux test. The diagnostic accuracy of all various procedures is reviewed and the scintigraphy value in the evaluation of GER in infants and children is discussed. This method is simple, safe more physiologic than other available examinations.

Adolescent↗
PubMedDate not supplied

[Chronic respiratory manifestations and gastroesophageal reflux. Value of the study of nocturnal pH measurement].

We have undertaken a study on continuous pH oesophageal monitoring on children with chronic respiratory symptoms and a gastro intestinal reflux proved by at least one positive test (baryum esophagogram, GE scintiscan, endoscopy). We have compared the data from 16 children with digestive symptoms and 9 controls with no sign of reflux. While all the parameters differs significantly between controls and patients with digestive symptoms, controls and respiratory symptoms, the only difference between "digestive" and "respiratory" patients occurs in the duration of the mean of the nocturnal reflux. Moreover the respiratory patients improved by the reflux symptomatic treatment had a mean duration of nocturnal reflux greater than un improved patients. A mean duration of nocturnal reflux over 4 minutes could have some predictive value.

Child↗