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Biomedical subjects

E Klaus

Publications and source records attributed to E Klaus.

At least 37 records · Page 2Linked to original sources
PubMed1985

Enzymuria of the rat: biorhythms and sex differences.

Alanine aminopeptidase, gamma-glutamyltransferase and N-acetyl-beta-D-glucosaminidase were measured daily over 65 days in 24-hour urine of male and female Wistar rats. The mathematical evaluation was based on the Fourier-analysis. The excretion of alanine aminopeptidase and gamma-glutamyltransferase was higher in male than in female rats. This sex-dependent difference was not observed for N-acetyl-beta-D-glucosaminidase. The excretion of the 3 enzymes followed a biorhythm with a dominant period of 7 days for gamma-glutamyltransferase and N-acetyl-beta-D-glucosaminidase and one of 9 days for alanine aminopeptidase. Biorhythms and sex differences of enzymuria should be considered in experimental designs.

Acetylglucosaminidase↗
PubMed1985

The understanding heart: aging parents and their favorite children.

This paper compares the characteristics of adult children who provide comfort and sympathy and serve as confidants to parents with those whom parents perceive as disappointing. Interview information from 117 couples having children who had left home was analyzed using aggregate and intrafamilial strategies. The latter analyses compared the characteristics of the selected child with those of her or his sibs instead of comparing the aggregate of selected children with the aggregate of their siblings. Differences in the findings from the 2 techniques are discussed. The findings confirmed the importance of daughters who live nearby as understanding children. More important than proximity among the factors influencing parental judgments on disappointing and understanding children were intergenerational shared interests and values.

Adult↗
PubMed1984

[Roentgen diagnosis of intervertebral disk calcification in children].

From an analysis of their own patients and of the radiological appearances of juvenile disc calcification as described in the literature, the authors have subdivided the evolution of this condition into three phases. The third phase (residual effects) is given the most detailed consideration.

Adolescent↗
PubMed1983

Enzymuria of the rat: the preparation of urine for enzyme analysis.

The effects of sample preparations by dialysis and gel filtration on the catalytic concentrations of alanine aminopeptidase, N-acetyl-beta-D-glucosaminidase, and beta-glucuronidase are described. Individual urines were collected during 24 hours on 3 consecutive days from 10 male rats. Gel filtration (Sephadex G25) was more effective than dialysis against water in the removal of inhibitors of N-acetyl-beta-D-glucosaminidase and beta-glucuronidase. For alanine aminopeptidase, slightly higher results were obtained by dialysis. Inhibitor contents varied from day to day. Activity decreases of beta-glucuronidase and N-acetyl-beta-D-glucosaminidase were found in some of the urine samples and interpreted as removal of activators. Gel filtration is recommended for the preparation of rat urine for the measurement of these three enzymes. The slightly inferior effect of gel filtration on alanine aminopeptidase should be disregarded for the sake of practicality.

Acetylglucosaminidase↗
PubMed1983

Vascular effects of piretanide. Studies on extrarenal action in several animal models.

4-Phenoxy-3-(1-pyrrolidinyl)-5-sulfamoyl benzoic acid (piretanide, Arelix) was studied for its vasoactive effects in several experimental models. In rat and rabbit thoracic aorta strips, piretanide dose-dependently attenuated contractions induced by norepinephrine (noradrenaline). When contractions were induced by KCl no concentration response curve could be established. Piretanide inhibited the vasoconstrictor response to norepinephrine and to KCl in the rat mesenteric vascular bed. IC50's of 0.5 mmol/l and 4.9 mmol/l, resp., were calculated. In bovine coronary artery strips piretanide caused a marked relaxation. The vasoconstrictor response to PGE2 in piretanide superfused preparations was attenuated in a concentration related manner. Infusion of piretanide (1 mg X ml-1 X min-1) in the isolated guinea pig heart produced a reversible increase of coronary flow. In both normotensive and spontaneously hypertensive bilaterally nephrectomized pithed rats piretanide caused a significant reduction of diastolic blood pressure. The results contribute to the understanding of the antihypertensive effect of piretanide.

Animals↗