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Biomedical subjects

E J Field

Publications and source records attributed to E J Field.

At least 145 records · Page 8Linked to original sources
PubMed1970

Rickettsial antibodies in multiple sclerosis.

The serum of subjects with multiple sclerosis or other degenerative neurological diseases and that of normal controls does not differ significantly in its content of antibodies to several rickettsial antigens. There is no evidence for a rickettsial aetiology of multiple sclerosis, and no grounds for an extended clinical trial of Le Gac's full method of treatment with antibiotics.

Adult↗
PubMed1969

Antilymphocytic serum in experimental allergic encephalomyelitis.

Antilymphocytic and antithymic sera (raised in rabbits) are highly potent in preventing or alleviating experimental allergic encephalomyelitis in guinea-pigs. Good results are obtained when treatment is begun as late as 10 days after challenge. No protracted disease was seen from the use of antilymphocytic serum. Attempts to use this serum therapeutically once the disease was clinically established gave equivocal results. Antilymphocytic serum appears to have a non-specific stressor effect as well as its specific action, and possibly this adrenocorticotrophic-hormone (antiphlogistic) effect may ameliorate a developing encephalitis. The presence of an antimacrophagic factor in antilymphocytic serum may be important in increasing local reaction to injection of the serum and perhaps also in diminishing the appearance of haematogenous elements in the nervous lesions.

Adrenocorticotropic Hormone↗