Search PubMed⌕ Search

Biomedical subjects

E Honda

Publications and source records attributed to E Honda.

At least 109 records · Page 6Linked to original sources
PubMed1987

Subarachnoid hemorrhage after preoperative embolization of a cystic meningioma.

We present a case of cystic meningioma accompanied by hemorrhage in the cyst and adjacent subarachnoid space that occurred while preoperative embolization in feeders of the tumor was being applied. The possible reason for the hemorrhage was the sudden dynamic changes in blood flow triggered by the embolization. The changes could have caused multiple ruptures of pathologic small vessels. We recommend that preoperative embolization should be used cautiously in treating cystic meningiomas because of a possible increase in bleeding from pathologic weak vessels.

Aged↗
PubMed1987

[The dumbbell shaped vertebral hemangioma developed in the pleural cavity and spinal canal].

A 44-year-old male patient visited our clinic complaining of back pain since January, 1984 and feeling of weakness at the lower extremities, sensory and vesicorectal disturbance since March of the same year. Hypesthesia and hypalgesia were observed at Th10 or below. The chest X-ray findings revealed an egg-sized tumor mass at the level of Th8. Metrizamide CT also demonstrated thoracic epidural mass. The characteristic findings of hemangioma showing delayed appearance of the tumor stain were also observed by angiography. The tumor was then confirmed as dumbbell-shaped hemangioma growing in the pleural cavity and the spinal canal. At the first surgical operation, total resection of the tumor in the spinal canal was performed by the postero-lateral approach. Although the second surgical intervention of total removal of the tumor in the pleural cavity had also been scheduled, the surgery was postponed because the patient had to return to work. The 2-year follow-up study revealed no recurrence of the tumor. And the tumor was found slightly diminished on chest X-ray. At present, the patient is still under observation. In this report, the authors discuss the therapeutic methods for thoracovertebral hemangioma including our case and reviewed in the literature related to this type of tumor.

Adult↗
PubMed1987

[A case of interhemispheric glio-ependymal cyst in a newborn infant].

An interhemispheric glio-ependymal cyst in a male neonate is reported. Neuroradiologically, the cyst, which had a septum like component within it, was located in the right frontoparietal interhemispheric and displaced the third and lateral ventricles. It had no communication with the ventricular system. As for anomalies associated with it, the total callosal agenesis and congenital hydrocephalus were revealed in CT scan. Angiogram suggested that polymicroglia accompanied with the cyst. It was confirmed that the cyst was divided into two parts by the septum during surgery. Microscopic examination showed that the cyst wall was composed of ependyma, connective tissue and glial cells. Choroid plexus component was also found in the septum. On the basis of the fact above, it was diagnosed interhemispheric glio-ependymal cyst. We believe that this interhemispheric cyst described above is a true cyst and differs morphologically and embryologically from the midline cyst which is produced with callosal agenesis and due to increased intraventricular pressure. In fact, the latter is an encystic third ventricle but not a true cyst. Both of them are, however, usually called interhemispheric cyst in the literature. We conclude that this case is appeared to be a true cyst because we can differentiate it from third ventricle by neuroradiological findings. We discussed nature of different interhemispheric cysts with callosal agenesis and suggested that recognition of the morphological relationship between the interhemispheric cysts and third ventricle was utmost important to make a correct diagnosis.

Agenesis of Corpus Callosum↗
PubMed1986

Mechanisms of neutralization by monoclonal antibodies to different antigenic sites on the bovine herpesvirus type 1 glycoproteins.

Monoclonal antibodies directed to different antigenic sites on bovine herpesvirus type 1 (BHV-1) glycoproteins were used to study the mechanisms of neutralization of the virus. Three nonoverlapping neutralizing antigenic sites, designated Ia, Ib, and Ic, were defined on gp87. Antibodies to site Ia which mediated viral neutralization without complement were effective on inhibition of virus adsorption. Antibodies to a single neutralization site on gp71, designated IIa, were able to neutralize the virus without complement even when they were incubated with the virus which had already adsorbed onto the cells. Antibodies directed against gp117 and antibodies against sites Ib and Ic on gp87 required complement for virus neutralization.

Antibodies, Monoclonal↗
PubMed1986

Non-invasive measurement in intracranial pressure and analysis of the pulse waveform.

Non-invasive measurement of the intracranial pressure (ICP) via the anterior fontanelle by using an applanation transducer has been performed. Recently, a new fontanometer using an applanation transducer has been developed in our department by improving the conventional Statham transducer, P-50 which is currently accepted for its high reliability. In this study, by analysing patterns of the ICP pulse waves obtained from this new fontanometer, its clinical evaluation has been made in 27 neonates and infants in intracranial pathologies. Analysing the ICP waveforms, the first peak (P1) was divided by the following second peak (P2) and the changes in P1/P2 were examined. A differential amplifier, a dP/dt detector, was also used to make it easier to identify the turning point on the pulse waves. The results obtained demonstrated that the waveforms of ICP in neonates as well as infants are influenced by not only the intracranial constituents but compliance of the container such as the scalp, cranium and the meninges.

Acute Disease↗
PubMed1986

[Neonatal subdural hematoma secondary to tentorial tearing--clinical analysis on 48 survived cases].

In order to evaluate the treatments of subdural hematoma in neonates and to observe their prognosis, we carried out clinical analyses on 48 survived cases in the past three years from Jan. 1979 to Dec. 1981. Based on CT observations, hematomas were grouped into four types according to their locations as follows: Type I, localized around the posterior interhemispheric fissure in 25 cases (52%); Type II, extending from the posterior interhemispheric fissure to the hemispheric convexity in five cases (10%); type III, extending from incisura to the posterior fossa in 15 cases (31%); and type IV, having subdural hematoma accompanied by intracerebral hemorrhage in three cases (7%). Intracranial pressure was measured via the anterior fontanelle in 13 cases. Ten patients who had extensive hemorrhage were found to exceed above 200 mmH2O in the pressure. Ages of the patients studied were 0 to 7 days old. There were 36 mature infants (75%) and 12 cases immature (25%). The maternal history of delivery was primiparous in 27 cases (56%). The fetal presentations were 38 cephalic (79%) and 10 suction deliveries (21%). The fundus oculi was examined on 32 patients. Retinal hemorrhage was noted in 12 cases. Operations were performed on 13 patients in total; one case in type I, four cases in type II, five cases in type III and three cases in type IV. Functional prognoses were found to be as follows; Type I; normal, 15 cases, abnormal, four and undetermined, six: type II; normal, four and abnormal, one: type III; normal, 13, abnormal, one, and undetermined, one: and type IV; normal, two and abnormal, one case.

Birth Injuries↗
PubMed1986

[Cystic meningioma associated with intratumor and subarachnoid hemorrhage during embolization--a case report].

We present a case of a cystic meningioma accompanied with hemorrhage in a cyst and adjacent subarachnoid space that occurred while preoperative embolization in feeders for the tumor was being applied. A 73-year-old male patient was admitted for a complaint of convulsion. Under CT examination, a tumor was observed at the left frontal convexity and found to be fed by the middle cerebral artery shown in the left cerebral angiograms. The tumor was diagnosed meningioma. After removing the tumor, we conducted histological study. Gross findings of its cross section had an atypical bleeding pattern which was resulted from the ruptures of the criss-crossing internal and external carotid arteries in the tumor. The findings indicated that the tumor was an angiomatous meningioma and contained meningotheliomatous components. The hemorrhage was occurred in the portion of the angiomatous meningioma. The possible reason for the hemorrhage was thought that sudden dynamic changes in blood flow which were triggered by the embolization. The sudden changes could have caused multiple ruptures on pathologic small vessels. Therefore, we strongly recommend that preoperative embolization should be proceeded with caution for exercising a cyst meningioma, since it could increase the possibility of bleeding from pathologic weak vessels.

Aged↗
PubMed1986

[The penetration of cefotaxime into the cerebrospinal fluid. Comparison between acute and chronic stages in intracranial diseases].

Two grams of cefotaxime (CTX) were administrated by drip infusion to 10 patients (11 material) with acute or chronic stage of intracranial diseases. Concentrations of CTX in the serum and the cerebrospinal fluid (CSF) were determined at 15, 30, 60, 120, 240 and 300 minutes after injection. The results obtained were summarized as follows: Serum levels: Peak levels of CTX in sera were 66.2 +/- 10.23 (S.E.) micrograms/ml in the acute stage group (ASG), and 75.7 +/- 31.39 (S.E.) micrograms/ml at 15 minutes after injection in the chronic stage group (CSG). There were no significant difference between the 2 groups. CSF levels: Peak levels of the drug in CSF were 1.35-4.32 micrograms/ml in ASG and 0.18-0.7 microgram/ml in CSG. Average concentration at 60 minutes after injection was 1.11 +/- 0.09 (S.E.) micrograms/ml in ASG and 0.30 +/- 0.08 (S.E.) micrograms/ml in CSG. The value in ASG was significantly higher than the value in CSG by t-test. The ratio between CSF and serum levels: The levels increased as time passed in both groups and the values in ASG were higher than those in CSG at all time points. Average ratios at 60 minutes after injection were 3.85 +/- 0.29 (S.E.)% in ASG and 1.12 +/- 0.50 (S.E.)% in CSG. The value in ASG was significantly higher than that in CSG by t-test. From the above results, it is considered that CTX is useful for the prophylaxis of postoperative infections in intracranial diseases.

Adult↗
PubMed1986

[Kleeblattschädel syndrome--a case report].

The Kleeblattschädel syndrome is a type of craniofacial dysostosis having a trilobar deformity of the skull associated with congenital hydrocephalus. We present here a case of the anomaly which we operated on a patient for cranial correction and orbital decompression. The case is a 2-month-old female who was born after 40 week-gestation by spontaneous vaginal delivery with cephalic presentation and observed no abnormality in her vital signs. She was transferred to a neonatal intensive care unit because of her trilobar deformity of the head and severe proptosis. Plain X-ray films of the skull indicated a number of digital markings at the calvarium. The triobar configuration was formed by symmetrical outward protrusion of the bilateral temporal squama and bulging the vertex which made a high valt. The coronal and lambdoid sutures which were prematurely closed together could not be distinguished individually. Both sides of temporal squama were found to be quite thin. She had severe shallow orbit due to the maxillary hypoplasia. A ventriculomegaly was seen in CT scan. Cranial corrections were took place in two stages. A V-P shunt was also done. The first surgery was conducted at three months old for advancing the bifrontal part and decompression of the orbits. Bilateral frontal bone was removed by craniectomy cutting along with both sides of the prematurely closed coronal suture in the back and to the supraorbital ridge in the front after making bicoronal scalp incision on supine position.(ABSTRACT TRUNCATED AT 250 WORDS)

Craniofacial Dysostosis↗