Biomedical subjects
Publications and source records attributed to E G Pedachenko.
An analysis of 97 cases indicates that the clinical manifestations of mild repeated head injuries do not reflect the real severity of the traumatic brain disease which determines the necessity of complex clinico-instrumental examination of these patients. Objective clinical and instrumental methods suggest that complete cure does not occur in mild repeated head injury in patients of all age groups.
An analysis of 463 patients operated upon for severe cranio-cerebral traumas has shown that one of the main factors improving results of treatment is using the methods of neurosurgical prophylactics of intracranial hemorrhages in the postoperative period. A considerably less incidence of intracranial hemorrhages can be achieved by using the inflow-outflow dialysis system, removing the crushed brain substance, suturing the dura mater to the periosteum at the borders of the bone defect. The ends of the ligature are taken out onto the skin through the holes in the center of the osseous flap.
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A comparative analysis of 408 cases of craniocerebral trauma (CCT) has revealed a considerable influence of hypertension on clinical manifestations of CCT. It has been found that in hypertensive patients the incidence of secondary acute impairments of the cerebral circulation predominantly of the ischemic type with less marked hypertensive and dislocation syndromes was 4-5 fold higher than in patients with normal blood pressure.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The condition is analyzed of the pro-oxidant-antioxidant balance in patients in the acute phase of craniocerebral injury. The higher the degree of craniocerebral injury, the more enhanced are lipid peroxidation processes, the more apparent is the decline in the function of the bodily antioxidant system. Changes in metabolic processes were at their greatest in patients beyond forty four years of age, especially in women with severe craniocerebral injury. The authors recommend including natural and synthetic antioxidants into a complex of measures designed to treat craniocerebral injury.
The paper presents early and late outcomes of treatment in 62 patients undergone paracentetic laser "diskectomy" for discogenic compressed syndromes of the neck. It shows the efficiency of surgery for radicular (92.9%) and myelopathic (92.8%) syndromes. Patients were selected for these interventions on the basis of clinical and neurological examinations, spondylography, MRI, and electric neuromyography. The main stages of an operation were as follows: local anesthesia, right-sided anterolateral access, X-ray guidance of the position of a needle, one-stage removal of herniated disks during multi-levelled injury during an intervention. The operation lasted 18 +/- 2.4 minutes. The mean hospital stay was 12 +/- 1.4 hours. The interventions were performed in 16 of 62 cases in the outpatient setting.
An analysis of 133 cases furnished a background to the study of features specific for the clinical course, symptomatology, diagnosis and surgical treatment of patients with multiple traumatic intracranial hematomas. The available clinical material was scrutinized in 3 groups of cases under observation (with "floor-wise", bilateral and "neighbouring" multiple intracranial hematomas) by using a complex set of up-to-date auxilliary diagnostic methods of investigation (EEG, echoencephalography, serial angiography, etc). The results of the surgical treatment were studied depending upon the specificity marking the clinical evolution of the disease, as well as upon the method and technique of the operative intervention.
The paper provides outcomes of treatment in 37 patients with cervical diskal hernias, operated on by endoscopic portal microsurgery. Surgery involved the use of video endoscopic techniques, microsurgery under fluoroscopic control. The duration of an operation was 22 +/- 2.7 min. Hospital stay was not more than 24 hours. Fair early and late outcomes were noted in 94.1% of the patients.
The specific features of craniocerebral trauma in diffuse toxic goiter were studied from analysis of 34 cases. The craniocerebral trauma aggravated the course of diffuse toxic goiter with the development of thyreotoxic crises in the first days after the trauma in one of five patients. The therapeutic tactics in thyreotoxic crisis and the preoperative and postoperative management of patients are discussed.
The paper presents the results of treatment in 15 patients with aggressive hemangiomas of the vertebral bodies, operated on by puncture vertebroplasty. The authors analyze current approaches to treating patients with this pathology, present criteria for aggressiveness of hemangiomas. The results of the treatment indicate that puncture vertebroplasty is highly effective and safe in treating patients with hemangiomas of the vertebral bodies.
The paper presents the results of percutaneous lumbar endoscopic diskectomy in 96 patients with discogenic lumbosacral radiculitis. Indications, contraindications, and surgical techniques are discussed. The intervention is shown to be highly effective (91.1%) in young patients with a relatively short history of the disease and hernias measuring as large as 8 mm. The paper analyzes complications and poor results of treatment using percutaneous lumbar endoscopic diskectomy.
It is shown that in the recent 2 decades the incidence of craniocerebral trauma increased from 4.8 to 7.2% among old-aged individuals and from 53 to 72% in the group of patients over 60. The dynamics of changes in the clinical course of mild craniocerebral trauma in 21% of old-aged patients were marked by secondary acute cerebral circulatory disorders which often led to a fatal outcome. Mortality rate in craniocerebral trauma at old age was 52.3%.