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Biomedical subjects

E Friedman

Publications and source records attributed to E Friedman.

At least 667 records · Page 37Linked to original sources
PubMed1978

Staff privileges for nonphysicians. Part 2: A sampling of hospital programs and privileges for nurse practitioners and physician's assistants.

Physician's assistants and nurse practitioners, once thought to be a possible answer to the maldistribution of physicians, have extended their roles into the hospital setting and are now performing in a number of fields. Several programs utilizing to varying extents the services of these nonphysician health care workers are presented along with the different systems used in limiting their privileges.

Medical Staff Privileges↗
PubMed1978

AHA/AWH convention report: VE going strong, new threats on the legislative front.

A mood of cautious optimism prevailed at the 1978 annual convention. Attendees were cheered by the success of the Voluntary Effort and recent legislative victories but warned that the next 18 months would be difficult. Two new threats on the legislative horizon--elimination of part B reimbursement for physicians in teaching hospitals and the Administration's national health insurance proposal--were discussed, as well as patient rights, medical record confidentiality, and new JCAH standards.

American Hospital Association↗
PubMed1978

Systemic tuberculosis initially seen as an oral ulceration: report of case.

A 67-year-old white man was seen for the treatment of a painful oral ulceration. His medical history was highly suggestive of systemic disease. Radiographs of the chest and cultures of sputum were positive for tuberculosis. The incidence, appearance, and characteristics of oral tubercular lesions have been presented. The diagnosis of tuberculosis should be considered along with carcinoma, syphilis, fungal disease, and trauma whenever granulomatous ulcerations appear in the oral cavity.

Aged↗
PubMed1978

Endophthalmitis caused by Propionibacterium acnes.

We treated a man who developed endopthalmitis six weeks after a seemingly minor injury. Cultures were positive for Propionibacterium acnes, an anerobic, Gram-positive rod that is a normal inhabitant of the conjunctiva but is rarely a cause of endophthalmitis. The patient underwent vitrectomy and lensectomy with intravitreal injection of antibiotics followed by systemic cephalothin and prednisone. Clinical and visual improvement was rapid.

Actinomycetales Infections↗
PubMed1977

Antidepressant drugs and dopamine uptake in different brain regions.

The effect of trycyclic antidepressants on 3H-dopamine uptake into synaptosomes obtained from rat striatum and mesolimbic cortical areas was examined. Chlorimipramine was found to be the most potent uptake inhibitor (IC50 of 3.2-3.8 X 10(-6) M) in both brain regions. Desmethylimipramine, protryptyline and iprindole were approximately one-half as potent (IC50 of 5.9-8.5 X 10(-6) M) in both brain areas. Kinetic constants obtained from Line-weaver-Burk plots in both areas revealed no alteration in Km for transport and a decrease in V max thus indicating a non-competitive inhibition. The effect of chlorimipramine on the release of 3H-dopamine from striatal synaptosomes required a concentration 10(-5) M for 50% release in 5 min. It is suggested that dopamine uptake inhibition may play some role in the action of tricyclic drugs, e.g., activation of schizophrenic psychopathology but that this action can not be solely responsible for their antidepressant properties.

Animals↗
PubMed1977

Incidence of recurrent herpes labialis and upper respiratory infection: a prospective study of the influence of biologic, social and psychologic predictors.

In a 3-year prospective study of recurrent herpes labialis (RHL) in a population of 149 student nurses, 40 to 50 per cent of the variance in incidence could be explained by a small group of variables. Measures of previous experience with RHL accounted for the largest fraction of the explained variance, followed by upper respiratory infection (URI) rate, socioeconomic status, and mood trait, in order of declining influence. Timing of RHL episodes was not related to phase of the menstrual cycle.

Antibodies, Viral↗
PubMed1977

Cardiovascular effects of delta9-tetrahydrocannabinol in conscious and anaesthetized dogs.

1. Temporal effects of delta9-tetrahydrocannabinol (THC) on heart rate and blood pressure in conscious dogs were compared to those in anaesthetized dogs. 2. In conscious dogs, THC in doses of 0.25 and 0.1 mg/kg resulted in maximal heart rate reductions of 48 and 41%, respectively, and in no significant change in blood pressure. 3. In anaesthetized animals THC in doses of 0.5 and 0.25 mg/kg caused a peak reduction in heart rate of 38 and 34%, and of blood pressure of 24 and 8%, respectively. 4. The results demonstrate that the bradycardia in response to THC in dogs is independent of the concomitant anaesthesia. 5. We conclude that the discrepancy between heart rate response to THC in dogs and in man is due to a species difference.

Anesthesia↗