Hemorrheologic changes following acute myocardial infarction.
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Biomedical subjects
Publications and source records attributed to E Ernst.
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Garlic has had a firm place in folk medicine since ancient times. More recent results are summarized here which show that extracts of the plant have an antimicrobial action, they are capable of lowering blood cholesterol and of reducing secondary vascular changes. They raise fibrinolytic activity and inhibit thrombocyte aggregation. Therefore the plant contains highly active therapeutic principles which appear to be particularly suitable for prophylaxis of arteriosclerosis.
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A large number of etiologies are hidden in the Raynaud Phenomenon, yet the clinical picture is quite uniform and shows particularly graded differences. Our knowledge of the underlying pathophysiological mechanism is incomplete. Neural, local, humoral and central nervous factors seem to play a role. A better understanding of these principles and their interplay is an essential condition for effective therapy. The present work attempts to summarize the results of recent research into the pathophysiology of the process and to relate them with modern forms of treatment which try to find a causal approach.
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This brief communication outlines recent experiments on the effects of buflomedil, a new vasoactive agent, on red cell deformability in patients with leg ischemia. In this randomized, double-blind-cross-over study, 10 patients received 200 mg buflomedil and matching placebo intravenously. Red cell filterabiltiy in these patients was significantly improved after buflomedil administration versus baseline values with no significant change in filterability versus baseline after placebo administration.