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Biomedical subjects

E Ernst

Publications and source records attributed to E Ernst.

At least 703 records · Page 39Linked to original sources
PubMed1987

Dose-effect relationship between smoking and blood rheology.

Five groups of male blood donors were investigated. The first group had never smoked, the second were ex-smokers, the third smoked between 10 and 20 cigarettes per day, the fourth between 21 and 40, and the fifth more than that. Haematocrit, white cell count, plasma and native blood viscosity, blood cell filterability and aggregation, plasma colloid oncotic pressure as well as fibrinogen were measured. Results show that smoking is associated with a progressive significant deterioration of the above haemorheologic variables. These changes are interpreted as an absolute and a relative polycythaemia possibly in conjunction with a chronic inflammatory process. It is concluded that smoking induces a dose-related increase in viscosity of blood among young men which is reversible by abstention.

Adult↗
PubMed1987

Cardiovascular effects of garlic (Allium sativum): a review.

Garlic (Allium sativum) has been used medicinally for centuries and still is included in the traditional medicine of most cultures. Recently, there has been renewed interest in its role in the treatment of cardiovascular diseases and its effectiveness in offsetting the risks of such conditions. The results of numerous studies are reviewed; they show that garlic can bring about plasma lipids normalization, enhancement of fibrinolytic activity, inhibition of platelet aggregation, and reductions in blood pressure and blood glucose. It is concluded that garlic has potential in the prevention and control of cardiovascular disorders.

Animals↗
PubMed1986

Cardiovascular risk factors and hemorheology. Physical fitness, stress and obesity.

To date there is little information about hemorheological data in the presence of secondary risk factors. Inter- and intraindividual comparisons of hemorheological parameters show that fitness has a significant influence on blood fluidity as quantified by ex vivo measurements of blood and plasma viscosity, red cell filterability and red cell aggregation. In fitter individuals blood is more fluid. Similar observations can be made with stress. Prolonged psychoemotional stress leads to a loss in blood fluidity and red cell filterability. Finally a comparison between excessively obese patients and healthy controls reveals a deterioration in hemorheological parameters in the obese group. These results, together with reports from the literature suggest that all accepted cardiovascular risk factors are associated with abnormalities in the flow properties of blood. It is proposed that partly the same phenomena are involved in the genesis of atherosclerotic lesions and influence rheological properties of blood.

Adolescent↗
PubMed1986

Blood rheology in vegetarians.

1. Blood rheology has been quantified by measuring blood and plasma viscosity, packed cell volume (PCV), erythrocyte filterability and erythrocyte aggregation in forty-eight voluntary vegetarians and compared with matched controls. 2. Results show that in vegetarians, values for PCV were lower than those in controls, leading to reduced native blood viscosity. In addition PCV-standardized blood viscosity was also decreased. This was brought about mostly by lower plasma viscosity. Erythrocyte rheology seemed to be unaltered. Stricter avoidance of animal products was associated with even lower values for these indices. 3. These observations are in agreement with the fact that other low-cardiovascular-risk groups show better than average blood fluidity. They are consistent with the hypothesis that in vitro measurements of blood rheology may provide signs of early atherosclerotic changes in vivo.

Adolescent↗
PubMed1986

Altered red and white blood cell rheology in type II diabetes.

Twenty-three patients suffering from type II, non-insulin-dependent diabetes were compared with matched controls. Suspensions with standardized white and red cell counts were filtered in a novel device capable of discriminating filter occlusion and cell transit time. Results confirm previous studies indicating that red cell deformability is impaired in diabetes. According to our findings, this may be caused by a slight overall loss of red cell fluidity together with the existence of a subpopulation of more markedly rigid erythrocytes. Furthermore, we demonstrate that white cell filterability is reduced in type II diabetes. This could be due to decreased white cell deformability, increased white cell adhesion, or both. Analysis of diabetic subgroups indicates that the white cell rheology is impaired to a greater extent in patients taking oral antidiabetic drugs than in patients controlled by diet alone. Altered white cell rheology could help to explain the pathological blood cell filterability frequently reported in diabetes. More important, impaired white cell rheology might significantly contribute to microcirculatory flow abnormalities jeopardizing O2 exchange in the terminal vascular bed.

Adult↗
PubMed1986

Sauna effects on hemorheology and other variables.

Acute sauna induces decreased blood fluidity as quantified by measurements of blood and plasma viscosity, hematocrit, red cell filterability, and aggregation. The effect is far less prominent when sauna treatment is continued regularly for eight weeks. In this case there are only minor changes in native blood viscosity and hematocrit together with slight variations in hematologic measurements, calcium, and serum protein pattern. Thus, from the hemorheology point of view, sauna leads to adverse effects predominantly acutely, while long-term effects seem negligible. Such aspects are worth considering in patients with high cardiovascular risks, and marked hypoperfusion.

Adult↗