Search PubMed⌕ Search

Biomedical subjects

E E Jones

Publications and source records attributed to E E Jones.

At least 91 records · Page 5Linked to original sources
PubMed1981

Complications of labor and delivery following uncomplicated pregnancy.

Renewed interest in less costly, less technologically oriented obstetrical care requires the accurate selection of women who may safely benefit from such alternatives. The distribution of complications of labor and delivery, among healthy women who had had uncomplicated pregnancies, was investigated by studying data from more than 240,000 birth certificates filed with the New York City Department of Health during the period 1971-1974. Complications of labor or delivery were reported for 21.0 per cent of births following apparently uncomplicated antepartum courses. Significantly higher rates of recorded complications were found for women who had initiated prenatal care earlier in pregnancy, for private patients as opposed to general service patients, for white patients compared to nonwhite patients, for married women than for unmarried women, and for better educated patients as opposed to those with less schooling. Labor and delivery complication rates were also noted to rise with maternal age. The positive association between earlier prenatal care and higher complication rates was found within all service, racial, marital, educational and age categories, and appeared to be independent of these variables. Factors which may contribute to these unexpected patterns, and further research to clarify them, are discussed.

Adolescent↗
PubMed1980

Multidimensional change in psychotherapy.

Assessed psychotherapy outcome for 177 patients who were seen for an average of 31 therapy hours with the Rating Scales for Outcome of Therapy and a Therapist Questionnaire. Results of a components analysis did not support Storrow's rational groupings of the Rating Scales into five dimensions and suggested that two general areas of psychological adjustment underlie the 11 scales. A second components analysis that included both outcome measures supports only in part the contention that when results from diverse outcome measures are factor analyzed, the factors necessarily are associated with method of measurement rather than substantive dimensions of change.

Adult↗
PubMed1980

Effect of histamine on bovine milk fatty acids.

Milk histamine content was monitored over the estrous cycle of several cows. Concentrations of histamine in the milk were maximal between days 0 and 1 and between days 4 and 7 of the estrous cycle. One quarter of a mammary gland of each of six cows was infused with 10 mg histamine free base. Milk samples were taken at 0, 4 and 10 hr, then analyzed for fatty acid composition. The 4-hr samples showed an increase in the proportion of short and medium length fatty acids, an increase in myristoleic, palmitoleic, oleic and linoleic acids and a decrease in stearic acid. The 10-hr samples showed a decrease in proportion of short and medium length fatty acids, a decrease in palmitic acid and an increase in stearic acid, while oleic acid and linoleic acid continued to increase from preinfusion. Linolenic acid showed no significant change during the experiment. Milk from one normal and one mastitic quarter of the mammary glands of several cows showed a significantly higher histamine content in mastitic milk than in normal milk.

Animals↗
PubMed1978

Drug choice as a self-handicapping strategy in response to noncontingent success.

In two closely related experiments, college student subjects were instructed to choose between a drug that allegedly interfered with performance and a drug that allegedly enhanced performance. This choice was the main dependent measure of the experiment. The drug choice intervened between work on soluble or insoluble problems and a promised retest on similar problems. In Experiment 1, all subjects received success feedback after their initial problem-solving attempts, thus creating one condition in which the success appeared to be accidental (noncontingent on performance) and one in which the success appeared to be contingent on appropriate knowledge. Males in the noncontingent-success condition were alone in preferring the performance-inhibiting drug, presumably because they wished to externalize probable failure on the retest. The predicted effect, however, did not hold for female subjects. Experiment 2 replicated the unique preference shown by males after noncontingent success and showed the critical importance of success feedback.

Achievement↗
PubMed1978

Black-white personality differences: another look.

Investigated the meaning of Black-White differences typically discovered on personality instruments by administering a pool of items derived from both the MMPI and California Psychological Inventory, as well as a group form of the Embedded Figures Test, to a sample of 226 black and white junior college students. A cluster analysis of the unexpectedly large number of inventory items significantly differentiating the two races produced reliable and meaningful configurations. Interpretations of race differences on these clusters and the EFT provide a new perspective on the meaning of Black-White personality differences.

Adolescent↗
PubMed1977

Regulation of Escherichia coli ornithine transcarbamylase by orotate.

Ornithine transcarbamylase from Escherichia coli, strain W, exhibits negative cooperativity with respect to ornithine, and the enzymatic activity is further regulated by orotate. The effect of orotate on ornithine transcarbamylase is dependent not only upon the carbamylphosphate concentration, but also upon the concentration of ornithine. At high concentrations of carbamylphosphate (10 mM), a conversion from negative cooperativity to positive cooperativity is observed with 10 mM orotate. At 1 mM carbamylphosphate, however, 10 mM orotate activates the enzyme at low ornithine concentrations, but as the ornithine concentration is increased above 5 mM, inhibition is observed. Thus, a regulatory link has been established between the pathways of arginine biosynthesis and pyrimidine biosynthesis, each of which utilizes carbamylphosphate.

Carbamyl Phosphate↗
PubMed1976

Postcoital luteinizing hormone release in male and female rabbits as determined by radioimmunoassay.

We have developed a homologous radioimmunoassay for rabbit luteinizing hormone (LH), which was used to measure LH levels in sera of male and female rabbits before and after copulation. The results demonstrated the following: (1) LH concentrations in male and estrogen-primed female rabbits are similar prior to coitus; (2) following coitus, LH levels rise within 3 minutes in both sexes and reach a peak or plateau within 15 minutes; (3) elevated LH concentrations are maintained at a plateau for at least 1 hour in females and then fall toward base line values; (4) an increase in serum LH to 300 ng/ml (10- to 11-fold) or greater is sufficient to cause ovulation and the formation of corpora lutea; and (5) the postcoital rise in LH levels is greater in estrogen-primed females than in nontreated males.

Animals↗
PubMed1976

Ornithine delta-transaminase activity in Escherichia coli: its identity with acetylornithine delta-transaminase.

Procedures that have been developed for the purification of acetylornithine delta-transaminase from Escherichia coli W also lead to the simultaneous purification of ornithine delta-transaminase. These two enzymatic activities have the same electrophoretic mobility and are identical immunochemically. Studies of inhibition kinetics demonstrate that the two substrates, acetylornithine and ornithine, compete for the same active site of acetylornithine delta-transaminase; thus, the ornithine delta-transaminase activity in E coli is due to acetylornithine delta-transaminase and not to a separate specific ornithine delta-transaminase.

Binding Sites↗
PubMed1976

Short-loop feedback control of luteinizing hormone in the rabbit.

A radioimmunoassay for rabbit luteinizing hormone (rLH) in which rLH shows no significant cross-reaction with human LH (hLH) or human chorionic gonadotropin (HCG) was employed to test for the existence of a short-loop feedback for LH in the rabbit. Two weeks after castration, hCG and hLH were administered intravenously to rabbits, and the effects on circulating rLH were measured. Purified hLH (10 ng or 100 IU) produced significant depression of blood rLH within 30-60 min of intravenous injection. Saline administered to the same animals produced no changes in rLH. Injection of hCG (2,000 IU) under the same conditions also produced a significant fall in rLH. However, hCG administered to rabbits castrated 6 wk prior to study failed to suppress endogenous rLH. These data demonstrate, by direct radioimmunoassay quantification of blood hormones, the existence of a short-loop negative feedback for LH in the rabbit. They also suggest that the sensitivity of the short-loop changes with time after castration.

Animals↗
PubMed1975

Alteration of regulation of arginine biosynthesis in Escherichia coli W by mutation to rifampin resistance.

The synthesis of acetylornithine delta-transaminase is induced by arginine and by rifampin in an arginine-inducible mutant of Escherichia coli W. A mutant of the arginine-inducible strain was isolated which is resistant to rifampin. The mutation which has brought about rifampin resistance has altered RNA polymerase and has simultaneously altered the regulation of arginine biosynthesis. Three of the enzymes of arginine biosynthesis, acetylornithinase, ornithine transcarbamylase, and argininosuccinase, show a greater rate of derepression and a 2--12-fold higher level of enzyme activity in the rifampin-resistant mutant than in the parent arginine-inducible strain. Acetylornithine delta-transaminase is no longer inducible by rifampin alone, and the level of inducibility by arginine plus rifampin has been reduced by 70%. The results indicate that RNA polymerase is involved in regulation of arginine biosynthesis in E. coli W.

Acetamides↗