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E Berkman

Publications and source records attributed to E Berkman.

40 records · Page 3Linked to original sources
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Antibiotic susceptibilities of Salmonella serogroups isolated from Turkish children.

This study is performed to show the serogroup distribution and in-vitro antibiotic susceptibilities of Salmonella species that cause either gastroenteritis with/without bacteremia or enteric fever at Hacettepe University Ihsan Doğramaci Children's Hospital. Of the 309 Salmonella strains evaluated, serogroup B was the most common isolate (56%) followed by serogroup D (33%). Antibiotic susceptibility tests using the disk diffusion technique revealed resistance rates of 43 percent for ampicillin, 41 percent for chloramphenicol, 29 percent for trimethoprim-sulfamethoxazole (SXT) and 32 percent for ceftriaxone among Salmonella serogroup B. The same rates were 10, eight, seven and zero percent for Salmonella serogroup D, and seven, 14, and zero percent for serogroup C, respectively. S.thypi strains susceptible to all antibiotics studied except tetracycline (33% resistant). No resistance was detected against the quinolones. The antibiotic resistance of Salmonella species isolated from children seems to be important, especially in serogroup B. Susceptibility tests should be considered in the antimicrobial therapy of Salmonella infections where indicated.

Child↗
PubMedDate not supplied

Antibiotic susceptibilities of enterococci isolated from Turkish children.

To evaluate the antibiotic resistance rates of enterococci isolated at Hacettepe Children's Hospital, in vitro antibiotic susceptibility tests were performed in 77 enterococci (32 hospital, 45 nonhospital strains) isolated from various clinical specimens in 1994. Microbroth dilution tests against ampicillin, vancomycin, gentamicin and streptomycin were performed according to the NCCLS standards. High-level resistance to aminoglycosides was investigated. Ampicillin resistance rates were 21.9 percent and 2.2 percent for hospital and nonhospital strains, respectively (p < 0.01). The same rates were 46.9 and 13.3 percent for gentamicin (p < 0.01), and 15.6 and 13.3 percent for streptomycin (p = 0.25). No resistance was detected against vancomycin. Six strains (7.8%) showed high-level resistance to both aminoglycosides studied. Special attention should be paid to enterococci isolated from hospitalized patients. Appropriate antibiotic use in serious infections can only be achieved by choosing an appropriate regimen according to antibiotic susceptibility tests. Periodic evaluation of the antibiotic susceptibility patterns of enterococci is necessary for the empirical treatment of infections due to these microorganisms.

Child↗
PubMedDate not supplied

Salmonella gastroenteritis in children.

Among 20,100 children with gastroenteritis admitted to Hacettepe University Ihsan Doğramaci Children's Hospital Diarrhea Training and Treatment Unit between April 1987 and December 1994, 508 Salmonella strains were isolated. Epidemiology, clinical pictures, laboratory findings, and outcome of these patients are discussed. Salmonella gastroenteritis represented 2.5 percent of all diarrheal cases during the study period. The highest number of isolations of Salmonella strains were reported between June and October. Salmonella serogroup B was the most common isolated strain (77%) followed by serogroup D (21%) and serogroup C (2%). Progressive decrease among group B isolations were noted between 1991-1994 with a concomitant increase in group D isolations. S. typhimurium was the most common serotype and overall represented 52 percent of the strains. Bloody diarrhea was found to be present in 27 percent of all cases. It is noted that the patients infected with group B strains had a higher rate of bloody diarrhea than the patients infected with group D strains (30% versus 15%, p < 0.05). Dehydration was present in 14 percent of the cases. We noted that severe dehydration (0.2%) and electrolyte disturbances (1.5%) were rare among our patients. None of these cases had a complication or an extraintestinal manifestation of Salmonella gastroenteritis. No deaths were reported.

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