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Biomedical subjects

E Bauer

Publications and source records attributed to E Bauer.

At least 199 records · Page 11Linked to original sources
PubMed1984

[Nutrition physiologic, immunologic and clinical parameters in prospective randomized patients by enteral or parenteral nutrition therapy following large intestine operations].

In a prospectively randomized study with 60 patients differences between enteral and parenteral nutrition were investigated especially with regard to short living proteins, immunoglobulins and clinical complications. Prealbumine as well as fibronectin and transferrin increased faster in enteral nourished patients postoperatively than in the parenterally nourished group. With this observation a reduced weight loss correlates in the enterally nourished group. From the immunoglobulins only IgM was significantly increased after enteral nutrition. An accumulation of postoperative infections seems to be in context with a delayed increase of IgM in the parenteral nourished group.

Aged↗
PubMed1984

[Operation or conservative therapy? New aspects based on further differentiation of emergency endoscopy findings in hemorrhage of gastrointestinal ulcers].

In a retrospective study the clinical courses of 121 patients with bleeding peptic ulcers were reviewed. The possibility for endoscopic prediction of recurrent bleeding was evaluated. The criteria specific to recurrent hemorrhage, which we found in bleeding ulcers during emergency endoscopy, led us to a modification of the Forrest-classification. All spurting arterial bleedings, which could be stopped by endoscopic means and all lesions with a big visible vessel in the ulcer crater had a high risk of recurrent bleeding. Therefore early surgical treatment should be performed soon after stabilisation of all vital functions and compensation of the blood loss. The emergency endoscopy enables not only an accurate diagnosis, but also a prediction and prognostic judgement of recurrent bleeding. This will give the surgeon valuable informations on deciding an operative or conservative treatment.

Emergencies↗
PubMed1984

Histologic abnormalities in routine biopsies of patients with esophagitis and different gastric acid secretion.

Intraepithelial eosinophilic granulocytes were previously reported to evidence prolonged acid reflux in patients with reflux esophagitis. The following study was performed to investigate whether or not these histologic abnormalities are specific to patients with esophagitis and high H+ ion activity of the gastric juice. Esophagitis was proved endoscopically in all patients. Biopsy specimens were obtained during endoscopy by forceps biopsy from the area involved. Afterwards an acid secretion test to determine basal and pentagastrin-stimulated H+ ion activity and a Bernstein test were performed. Histologic findings were correlated with the results of the acid secretion test. In this study, the occurrence of intraepithelial eosinophils was similar in patients with high and with low gastric acid output, but was overall low in these patients and has not proved to be a specific diagnostic criterion for reflux.

Adult↗
PubMed1983

[Permeation of triamcinolone acetonide and zinc oxide from a shake lotion].

Triamcinolone-acetonide crystals suspended in a zinc oxide shake lotion permeate the deeper skin layers especially if applied to a damaged horny layer. The influx rate of the corticosteroid is approximately 20 times higher in damaged skin (e.g. removing of horny layer by stripping) than in healthy skin. Zinc oxide is absorbed by the middle and lower layers of the horny layer respectively epidermis, out of the triamcinolone-acetonide shake lotion. The corticosteroid and zinc component as well as a physical properties of the shake lotion have a therapeutical effect.

Adult↗
PubMed1983

[Occlusion of chronic decubitus ulcers by musculocutaneous gluteus maximus flaps].

Early coverage of long-standing pressure sores in patients with paraplegia, multiple sclerosis and prolonged immobilisation due to fractures of the lower extremities should be performed in order to avoid further bone destruction and septic complications. Musculocutaneous flaps offer several advantages in covering infected soft tissue defects and proved to be superior to cutaneous flaps. Surgical repair of pressure sores requires a prospective selection of available musculocutaneous flaps. Planning should include the possibility of ulcer recurrence or of pressure sores in adjacent regions. Sacral and ischial pressure sores were covered by a musculocutaneous gluteus maximus flap in 11 patients.

Adolescent↗
PubMed1982

[Frequency and significance of infections due to Yersinia enterocolitica in "acute appendicitis" (author's transl)].

In 352 patients who were hospitalized with symptoms of an acute appendicitis, Yersinia infection were determined in 18.2% of the cases by cultural and serological methods. Infections due to Y. enterocolitica (Y. e.) serovar 0:3 were approximately 6 times more frequent than those due to Y. e. serovar 0:9. Yersinia pseudotuberculosis (Y. pstbc.) could only be isolated in one patient from a mesenterial lymph node. In another case Yersinia serovar 0:6 could be isolated as well as Y. e. serovar 0:3. The majority of the infections were found in the age group 9-12 years. The incidence was highest in the summer months June-August.

Acute Disease↗
PubMed1981

Spread of R-plasmids among Escherichia coli causing urinary tract infections.

The incidence of multiple-antibiotic resistance among Escherichia coli isolated from urinary tract infections at Charing Cross Hospital, London, increased over the last 10 years, and its distribution was related to O-type. Among strains of the eight O-types most frequently causing such infections at this hospital, O4, O9, and O18 had a high incidence of multiple resistance (35, 22, and 19%, respectively); O2 and O6 had a intermediate incidence (14 and 11%, respectively); and O7, O1, and O75 had a low incidence (8, 6, and less than 3%, respectively). This nonrandom distribution appears to be a consequence of unequal plasmid recipient ability. After overnight mating with antibiotic-resistant donors, R-plasmid infection frequencies among antibiotic-sensitive urinary tract isolates differed by up to 10(5)-fold, and such differences were correlated with the variation in the incidence of antibiotic resistance among the O-types. The inherent differences in the ability to achieve significant R-plasmid spread, which appear to be determined by the host, not the plasmid, may be compounded in some cases by the inhibition of potential mating partners by colicin production.

Ampicillin↗
PubMed1981

In vivo sampling and biochemistry of tracheobronchial secretions in the fowl. Influence of sulfurdioxide inhalation.

A new method for collecting tracheobronchial secretions from the anesthesized fowl has been developed. Sulfurdioxide inhalation leads to a highly significant increase of mucus output (wet weight), 320 % of control. Glycoprotein output is increased by only 50 %. Thus glycoprotein concentration is lowered to about 1/3 that of the control group. The carbohydrate pattern of the glycoproteins shows no significant alteration after sulfurdioxide treatment. Isoelectric focusing of te glycoprotein subunits derived from papain digestion shows no difference between the macromolecular pattern of the control and SO2 group.

Animals↗
PubMed1978

8-Methoxypsoralen (8-MOP) in human skin: penetration kinetics.

Penetration kinetics of 8-methoxypsoralen (8-MOP) into human skin have been investigated under in vitro conditions. The dependence of the resulting tissue concentration on time of penetration, drug concentration in the applied preparation and vehicle composition has been studied. Tissue concentration of the drug was found to increase with time of penetration; however, in both horny layer and epidermis, this increase was followed by a significant decrease in concentration, (after 100 to 300 min), although a large amount of unpenetrated drug was present on the horny layer surface at all times. In contrast to this, 8-MOP accumulated in the lower corium and subcutis and reached concentrations higher then those found in the upper corium and epidermis. This accumulation of the drug is a consequence of the in vitro conditions and its amount is proportional to that amount that under in vivo conditions would have been taken up by the capillary system. Penetration was dependent on vehicle characteristics and was found to increase with increasing polarity of the vehicle. The penetration was found to be directly proportional to the applied concentration; however, the percentage of the drug that actually penetrated was inversely proportional to the applied concentration.

Dose-Response Relationship, Drug↗