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Biomedical subjects

E A Vagner

Publications and source records attributed to E A Vagner.

At least 55 records · Page 3Linked to original sources

[Mechanisms of the activating effect of a closed chest injury on the immune response].

Experiments on male Wistar rats weighing 180-240 g have demonstrated a stimulatory effect of closed chest trauma (CCT) on immune response to T-dependent antigen. The enhancement of immune response correlated with the growing of T but not B cell number in the spleen. Thymectomy completely abolished the posttraumatic activation of antibody production. The enhancement of immune response was also noted after thoracotomy. The combination of thoracotomy with thymus trauma did not give, however, such an effect. The immunomodulatory effect of the CCT is concluded to be non-specific, which is mediated by the T cell system.

Animals↗

[Clinical and experimental data from a study of combined chest injuries].

The experience of treatment of 400 patients with severe associated traumas of the thorax has shown the potentiating action of different damages to result in new clinical quality responsible for a crisis of vital functions. In the every fourth patient there occurred dangerous for life progressing disorders in the respiration and hemodynamics. The methods of treatment were determined by the leading injury and the degree of disturbances in the respiration and blood circulation. Urgent operations were made for vital indications.

Abdominal Injuries↗