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E A Kovalenko

Publications and source records attributed to E A Kovalenko.

95 records · Page 6Linked to original sources
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[The comparative characteristics of the effect of continuous ischemia and ischemia with periodic reperfusions on the function and metabolic indices of the rabbit kidney].

Continuous 40-min ischemia and ischemia with reperfusion (10 min of ischemia and 10 min of reperfusion) induced by ligation of the vascular kidney crus were compared in experiments on 17 New Zealand rabbits. Both in continuous and interrupted (in period 4) ischemia resulted in the growth of pO2 cortical layer which is likely to be due to reduced oxygen utilization of the cells caused by metabolic and renal function disorders. Examination of lipid peroxidation activity determined similar activation of this process in both ischemic variants. In spite of the fact that both continuous and interrupted ischemias induced similar hyperoxygenation of the cortical substance and the same activation of lipid peroxidation, functional damage was less severe in experiments with interrupted ischemia.

Animals↗
PubMedDate not supplied

[The amino acid and monosaccharide composition of the extracellular sialo-specific lectins in bacteria of the genus Bacillus].

Chemical composition of extracellular sialo-specific lectins of Bacillus genus bacteria has been studied. It is shown that these biopolymers are glycoproteins distinguished by the quantitative and qualitative composition of proteins and hydrocarbons. It is established that the given bacteria can synthesize one or two extracellular lectins one of which represents N-asparagine-bound glycoprotein, while another one belongs to O-serine/threonine-bound glycoproteins.

Amino Acids↗
PubMedDate not supplied

[The carbohydrate specificity of the extracellular lectins in bacteria of the genus Bacillus].

The paper presents the study of interaction of extracellular sialo-specific lectins of Bacillus genus bacteria with different types of erythrocytes and affinity of these biologically active substances to derivatives of N-acetylneuramine acid and natural sialo and asialo conjugates. It is established that lectins under study possess a very narrow carbohydrate specificity and distinguish strictly definite carbohydrate structures. The identification processes first of all require the availability of N-glycolylneuraminic acid in the structure of receptors, and to the less extent of alpha-isomer of N-acetylneuraminic acid in O-acetylated form added to terminal galactose alpha 2-6-or alpha 2-3-bonds.

Animals↗