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Biomedical subjects

D Wood

Publications and source records attributed to D Wood.

At least 235 records · Page 13Linked to original sources
PubMed1976

Further investigation of Coleman's Level Hypothesis.

Volunteers (16 male and 17 female) from introductory psychology courses were used to investigate Coleman's rationale in support of the Levels Hypothesis. Projective stimuli from parts of the Rorschach, TAT, and Sentence Completion techniques were presented, and subjects asked to rate how much the stimuli and their responses said something about themselves, their fathers, or mothers, to determine their awareness of the personal relevance of the stimuli and responses. Results indicated that both the stimulus and response ratings varied as expected at the .01 level of significance, thus supporting Coleman's rationale.

Journal Article↗
PubMed1976

Reported drinking among posttreatment alcohol abusers: a preliminary report.

Posttreatment drinking behavior and job effectiveness ratings by supervisors are compared at 6, 12, and 24 months follow-up for young (age 25 and younger) and old (age 26 and older) male alcohol abusers admitted to Naval Alcoholism Rehabilitation facilities. Follow-up results indicate that: (1) large percentage of subjects were rated effective at their work following treatment; (2) effective subjects drank significantly less than noneffective subjects; (3) young subjects tended to drink significantly more than old subjects; (4) of those rated effective at their work, young subjects drank more and abstained less than did old subjects; (5) drinking behavior and work effectiveness ratings appear to remain consistent over the three follow-up periods. Some implications and limitations of the present study are discussed.

Adolescent↗
PubMed1976

The measurement of skin blood flow in peripheral vascular disease by epicutaneous application of Xenon133.

Radioactive xenon133 applied epicutaneously was used to study the skin blood flow below the knee in sixteen normal subjects, in eight patients with peripheral vascular disease not requiring amputation, and in a blind study of twenty-nine patients requiring amputation. Following these twenty-nine amputations, the flow rates were made known and correlated with the rates of healing. When the flow rates were above 1.5 milliliters per minute per 100 grams of tissue (skin), the wounds generally healed. In thirteen other patients, Syme or below-the-knee amputations were performed on the basis of the flow rates, and all of the wounds healed. The test, therefore, is now used routinely prior to amputation for peripheral vascular disease as an adjunct to clinical judgment in the determination of the level of amputation.

Adult↗
PubMed1975

Detection of acute myocardial infarction by technetium-99m polyphosphate.

Experimental work has shown that technetium-99m (99mTc) pyrophosphate accumulates in recently infarcted myocardium and can be detected by external imaging techniques. Twenty-two 99mTc polyphosphate myocardial studies were performed in 17 patients (in 3 after cardiac surgery) 3 to 20 days after myocardial infarction. Seventeen myocardial studies were performed in 17 control patients (in 6 after cardiac surgery). Twenty millicuries of 99mTc polyphosphate was injected intravenously 60 to 120 minutes prior to gamma camera imaging in several views. Myocardial images were processed by the Gamma-11 computer system using standardized background subtraction and contrast enhancement. Results of 16 myocardial studies performed 4 to 20 days after transmural myocardial infarction in 12 patients were positive in 13 instances and questionable in 1. The location of the myocardial infarction by imaging corresponded to location by standard electrocardiograhic criteria in 8 of the 10 patients with positive findings. In five patients with nontransmural myocardial infarction, results of myocardial imaging were positive in two, questionable in one and normal in one. In one patient with questionable findings results were normal when imaging was repeated 16 days after nontransmural myocardial infarction. Results of 17 control myocardial imaging studies were normal in 16 and questionable in 1. Therefore, 99mTc polyphosphate myocardial imaging appears promising in the detection and location of transmural myocardial infarction. Its accuracy in detecting nontransmural myocardial infarction may be increased with greater experience and development of sophisticated digital analysis techniques. The method may prove useful in clinical situations such as cardiac surgery in which standard diagnostic aids are difficult to interpret.

Acute Disease↗
PubMed1975

Subsensitivity to epinephrine following the administration of epinephrine and ephedrine to normal individuals.

Cardiovascular and metabolic responses to exercise and consecutive epinephrine infusions 24 hours apart were measured in 7 normal individuals before and following a week's administration of ephedrine sulfate. There was evidence of less beta adrenergic response to the second control epinephrine infusion compared to the first control infusion, and the depression of the rise in blood lactate was significantly different. A week of ephedrine produced more profound depression of the beta adrenergic responses to epinephrine with significant differences in the rise in blood glucose and lactate, and the pulse and blood pressure responses. Furthermore, these same responses remained significantly altered when a second epinephrine infusion was performed 36 hours following the last dose of ephedrine. The alterations in the response to epinephrine induced by ephedrine are consistent with the concept of effector cell "subsensitivity," an adaptive response to prolonged excessive stimulation.

Analysis of Variance↗