Adoption studies of alcoholism.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to D W Goodwin.
Explore the source record for details and available documents.
This radiologic study using hemisected dog jaws was undertaken to determine whether or not tomographic techniques would be superior to standard dental x-ray techniques in detecting prepared periodontal defects within the cancellous bone of dog jaws. Specifically, it was done to determine whether or not tomography might be a reliable method of checking for bone fill in periodontal bone-grafting therapy. As an additional measure, a radiographic study, using a hemisected dog mandible and standard dental x-ray techniques, was undertaken to determine whether lesion size or cortical plate involvement was the determining factor in radiographic visibility. When tomographic techniques were used 55% of thirty-one prepared defects were visible, while standard dental x-ray techniques detected 29% of the same defects radiographically. The differences in detection rate were not statistically significant when analyzed by chi square. Although tomography resulted in radiographic visibility of a greater number of prepared defects, it is not reliable enough to replace re-entry procedures for documentation of bone fill in clinical studies of periodontal bone-grafting procedures. In the additional study it was determined that cortical plate involvement was the determining factor in radiographic visibility of bony defects.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Being born to an alcoholic parent clearly raises the risk that a man will become an alcoholic, as shown by studies of adopted sons of alcoholic and nonalcoholic biologic parents. Being raised by an alcoholic parent, however, seems not to increase this risk. Alcoholics may possess some sort of biochemical tolerance for alcohol, perhaps based on more efficient detoxification mechanisms than those of moderate drinkers.
Following the ingestion of alcohol, Orientals experienced smaller decreases in serum hydrocortisone levels than did Occidentals.
Explore the source record for details and available documents.
Computerized transaxial tomography (CTT) studies of 12 young men having histories of heavy cannabis smoking revealed no evidence of cerebral atrophy.
Forty-nine daughters of alcoholics were compared to 47 daughters of nonalcholics; both groups of women (average age, 35 years) had been adopted by nonrelatives early in life. Two women in each group were alcoholic or problem drinkers. Although this is above the expected rate of alcoholism among women, the numbers are too small to draw definite conclusions. Almost all were light drinkers. Daughters of alcoholics had no more depression than controls, indicating that alcoholism in the biological parents did not increase the risk of depression in daughters raised by foster parents. Environmental factors may be important in both alcoholism and depression in women, since both tended to be correlated with psychopathology in the foster parents.
This report completes a series of studies conducted in Denmark comparing drinking patterns and psychopathology in adopted and nonadopted children of alcoholics. Sons of alcoholics had higher rates of alcoholism than controls, whether raised by their alcoholic parents or by foster parents. They did not have more psychopathology otherwise. Daughters of alcoholics, adopted and nonadopted, had a higher rate of alcoholism than was the expected frequency in the general population, but so did controls in the adopted group; neither group had higher rates of other psychopathology, eg, depression. However, daughters of alcoholics raised by their biological parents had significantly more depression.
The relationship of the volume of the uterus to the bipartial diameter in single, twin, triplet and abnormal gestations was determined. The relationships are linear and the populations of single and multiple pregnancies fall into distinct groups. Correlation of the uterine volume and biparietal diameter also establishes an objective basis for diagnosing the presence of polyhydramnios ,fetal hydrocephalus, or any abnormality that produces a distortion of the normal utere volume relationship.
Explore the source record for details and available documents.
The authors observed the effect of marijuana on carbohydrate metabolism in fed and fasting states in chronic marijuana users. They found no hypoglycemia in 7 patients who were given marijuana after fasting for 24-72 hours. They also found no significant difference in carbohydrate tolerance and no hypoglycemia during an oral glucose tolerance test in 10 patients who smoked placebo or marijuana on alternate days. They conclude that marijuana has no effect on carbohydrate metabolism in the fed or the fasted state in well-nourished chronic marijuana users.