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Biomedical subjects

D Voet

Publications and source records attributed to D Voet.

At least 37 records · Page 2Linked to original sources

Noninvasive diagnosis of superior sagittal sinus thrombosis in a neonate.

A newborn boy presented within the first day of life with moaning, anemia, and thrombocytopenia. The clinical syndrome resulted from thrombosis of the posterior part of the superior sagittal sinus due to impression at birth of the tip of the occipital squama. Both computed tomography and ultrasound scans were valuable noninvasive tools for documentation of the thrombus itself and the cerebral sequelae. Color Doppler ultrasound scan confirmed the absence and reappearance of flow in the superior sagittal sinus.

Birth Injuries↗

Arcuate ligament syndrome mimicking celiac occlusion.

In a patient with weight loss and a systolic epigastric murmur, aortography demonstrated positional celiac axis occlusion. Color Doppler imaging of the celiac axis showed occlusion in the supine position, but patency was documented during deep inspiration and with the patient in the upright position. This report documents a rare example of extreme celiac axis compression with position-dependent celiac patency.

Adult↗

Pseudoxanthoma elasticum: similar autosomal recessive subtype in Belgian and Afrikaner families.

A multidisciplinary survey of the clinical and genetic characteristics of 26 Belgian and 32 Afrikaner families with biopsy-proven pseudoxanthoma elasticum (PXE) was undertaken. The major PXE phenotype emerging from this study is very similar in both patient groups and is characterized by severe ophthalmologic manifestations with variable, mild cutaneous and vascular symptoms. In the families with more than one affected relative, segregation analysis is compatible with autosomal recessive inheritance in both groups. It is suggested that the PXE phenotype of these Belgian and Afrikaner patients is distinct from the other recognized PXE subtypes. The phenotypic resemblance in both patient groups raises the question whether a similar genetic mechanism is involved.

Adult↗

Floating thrombi: diagnosis and follow-up by duplex ultrasound.

The clinical features and evolution of floating thrombi (FT) diagnosed by duplex ultrasound were examined. In 76 consecutively diagnosed above-knee deep venous thromboses the prevalence of FT was 18%. Of 44 FT diagnosed in 39 patients, 18 (39%) were located in the common femoral, 12 (26%) in the popliteal and seven (15%) in the external iliac veins. Serial duplex examinations revealed that 31% of FT in the iliofemoral segment disappeared 33% remained unchanged and 36% adhered to the vein wall within 2 weeks following diagnosis. After 3 months, 87% of the floating segments had disappeared, irrespective of the localization or therapeutic regimen. Thirteen patients experienced pulmonary embolism before (12/13) or following (4/13) diagnosis of floating thrombosis; three of four superficial femoral vein FT embolized. Fifteen per cent of the patients with FT died during the study period and 28% of the thrombi were associated with a malignant neoplasm; the incidence of malignancy was 60% in superficial and 39% in common femoral vein FT.

Adult↗

Crystallization and preliminary X-ray studies of recombinant human granulocyte-macrophage colony stimulating factor.

Human granulocyte-macrophage colony stimulating factor (hGM-CSF) is an important regulator of growth and differentiation for mononuclear and polymorphonuclear phagocytes. Here we report the crystallization and preliminary X-ray studies of Escherichia coli-expressed hGM-CSF. The crystals are orthorhombic, with the space group P212121, and have unit cell dimensions a = 46.62 A, b = 58.73 A and c = 126.42 A. Recombinant hGM-CSF crystals diffract X-rays to 2.4 A resolution and are thus suitable for X-ray structural studies.

Colony-Stimulating Factors↗

Cranial ultrasound after forceful midpelvis vacuum extraction at term.

The heads of 28 non-hypoxic, full-term infants of normal gravidas delivered by forceful vacuum extraction were examined with ultrasound during the early neonatal period. All echographic findings were normal and all neonates had an uneventful evolution during the first week of life. Addendum: Since this article was completed, a massive intracranial haemorrhage occurred in a non-hypoxic full-term newborn after elective midpelvic vacuum extraction. The intervention was performed by a resident who, despite the guidelines did not call the senior obstetrician after three unsuccessful attempts to extract the fetus. The head was stationed, 2 cm above the level of the ischial spines, not completely flexed with the occiput in the right-anterior position. The newborn died at the age of 3 hours. Autopsy showed a tear of the tentorium cerebelli and the vena cerebri magna.

Brain Injuries↗

[Echographically controlled ventricle punctures].

Ventricular taps are performed either for diagnostic or for therapeutic purposes. They are not free of risks. A new technique is presented, in which the placement of the needle is echographically monitored. Fifteen punctures were done in five children. All punctures were successful at first attempt, and were uneventful.

Cerebral Hemorrhage↗

Ventricular taps in the neonate under ultrasonic guidance. Technical note.

A method of ultrasonically guiding ventricular taps in children is described. The needle is introduced through a needle guide in the ultrasound field of a sectorscanner. The direction of the needle is accurately determined and the needle itself is clearly visualized on the television monitor during its introduction into the brain. The results of seven punctures are presented. All these punctures were successful at the first attempt, and no complications occurred.

Cerebral Ventricles↗

Transabdominal real-time sonographic sector-scanning of bladder, seminal vesicles and prostate: technique and normal anatomy.

There is a wide application of diagnostic ultrasound in urology. Hitherto the transrectal and transurethral approach for evaluation of the pelvic organs has been used much more often. However, since the development of high resolution real-time sector-scanners, the transabdominal suprapubic approach through the full bladder has become more promising. Using this technique which, as a screening procedure, is most acceptable for the patient, detailed normal anatomy can be seen such as the ureteric orifices, the base plate, the proximal part of the urethra, the seminal vesicles and the ampullae, the ejaculatory ducts and the zonal anatomy of the prostate. In this report, the sonographic appearance of these various structures is correlated with anatomical data and the advantages of the transabdominal approach are discussed.

Female↗