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Biomedical subjects

D Tian

Publications and source records attributed to D Tian.

At least 73 records · Page 4Linked to original sources
PubMed1989

[Study of mechanisms in the pathogenesis of myelodysplastic syndrome: changes in lymphocyte subpopulations].

The mechanism of pathogenesis in myelodysplastic syndrome (MDS) is still unknown up to the present day, but examination of blood and bone marrow from 22 patients with MDS showed that the majority had low lymphocyte counts in bone marrow. Using monoclonal antibodies (MoAbs) OKT3, OKT4 and OKT8 combined with SRBC rosettes, the authors found that there was a significant decrease of OKT3-defined Pan-T lymphocytes in peripheral blood. This reduction was primarily confined to the OKT4-defined helper subset, but there was a relative increase in the OKT8-defined suppressor subpopulation. As a result, the ration OKT4/OKT8 was reversed. The data of MLC test also showed abnormalities of cell-mediated immunity function in the patients. The significance of these observed changes in the pathogenesis of MDS was discussed.

Adolescent↗
PubMed1989

[Technical problems on right lung transplantation].

This report describes the technique of the allo-transplantation of the right lung of an adult mongrel dog. Compare to the transplantation of the left lung, we found several pitfalls in the right lung transplantation. 1) The intraatrial groove of the recipient must be divided carefully just at the middle of the right and the left atrium in order to make a generous cuff for the left atrial anastomosis. 2) It is preferable to divide azygos vein to perform easy anastomosis of right pulmonary artery and right bronchus. 3) Care must be taken to make left atrial cuff in donor lung since we did not divide intraatrial groove in the donor animal. It was necessary to make the left atrial cuff with a part of the right atrium attached.

Anastomosis, Surgical↗